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Disruption of the odour-mediated mating behaviour of Plodia interpunctella using high-frequency sound

Indian meal moths, Plodia interpunctella Hubner ( Lepidoptera: Pyralidae), have ears which are sensitive to high-frequency calls produced by echolocating, insectivorous bats. The influence of artificially generated, high-intensity, ultrasound signals (25 kHz, 106 dB SPL at 1 m distance) on different parameters involved in the odour-mediated mating behaviour of this species and its potential use in

Alpha-adrenoceptors and benign prostatic hyperplasia: basic principles for treatment with alpha-adrenoceptor antagonists.

The selective blockade of alpha1-adrenoceptors (ARs) is now a well-accepted and widely used treatment for patients presenting with lower urinary tract symptoms (LUTS) associated with benign prostatic hyperplasia (BPH) and bladder outlet obstruction. The sites of action of the currently used alpha1-AR antagonists when relieving LUTS have not yet been established, but it seems clear that effects on

Cyclic nucleotide phosphodiesterase 3B is a downstream target of protein kinase B and may be involved in regulation of effects of protein kinase B on thymidine incorporation in FDCP2 cells

Wild-type (F/B), constitutively active (F/B*), and three kinase-inactive (F/Ba-, F/Bb-, F/Bc-) forms of Akt/protein kinase B (PKB) were permanently overexpressed in FDCP2 cells. In the absence of insulin-like growth factor-1 (IGF-1), activities of PKB, cyclic nucleotide phosphodiesterase 3B (PDE3B), and PDE4 were similar in nontransfected FDCP2 cells, mock-transfected (F/V) cells, and F/B and F/B-

The role of public policy in advancement of product service systems

This article discusses developments in the area of product service systems (PSS) and the need to facilitate the proliferation of the PSS approach through public policies. The article argues that policies that establish the framework conditions for environmental improvement are preferable to detailed legislation as they favour environmentally superior PSS. However, there is also a need for more spe

Neonatal chronic sympathectomy in normotensive rats affects pial arteries: enhanced stiffness and reduced capacity to dilate

The functional implication of previously shown effects on pial wall morphology by sympathectomy was tested. Following either ganglionic or pre-ganglionic denervation in 1-week-old rats the passive arterial compliance was reduced in basal cerebral arteries of 20-week-old normotensive, but not of hypertensive animals. The magnitude of the denervation induced stiffness was similar to the alteration s

Future RISING experiments at relativistic energies

The proposed experiments for the first RISING (Rare ISotope INvestigations at GSI) campaign will exploit secondary unstable beams at relativistic energies in the range from 100 MeV/u to 400 MeV/u. The RISING spectrometer will be employed for relativistic Coulomb excitation and for high-resolution gamma-spectroscopy experiments after secondary nucleon removal reactions and secondary fragmentation.

Key cofactors of Photosystem II cores from four organisms identified by 1.7-K absorption, CD and MCD

Active Photosystem II (PS II) cores were prepared from spinach, pea, Synechocystis PCC 6803, and Thermosynechococcus vulcanus, the latter of which has been structurally determined [Kamiya and Shen (2003) Proc Natl Acad Sci USA 100: 98-103]. Electrochromic shifts resulting from Q(A) reduction by 1.7-K illumination were recorded, and the Q(x) and Q(y) absorption bands of the redox-active pheophytin

Parents' experience of hospitalization: different strategies for feeling secure

Twenty parents of boys (ages 2-14 years) hospitalized for hypospadias repair in a pediatric surgery department in Sweden, were interviewed concerning their experience when their child was hospitalized. A qualitative analysis of the interviews indicated that the most important issue to the parents was finding security at the hospital. Parents manifested one of three different strategies that enable

Macrophages suppress T cell responses and arthritis development in mice by producing reactive oxygen species

Reduced capacity to produce ROS increases the severity of T cell-dependent arthritis in both mice and rats with polymorphisms in neutrophil cytosolic factor 1 (Ncf1) (p47phox). Since T cells cannot exert oxidative burst, we hypothesized that T cell responsiveness is downregulated by ROS produced by APCs. Macrophages have the highest burst capacity among APCs, so to study the effect of macrophage R

Numerical modelling of micro-droplet formation

The formation of micro-droplets due to a pulsative micro-jet (width of 40 mu m) is studied using the 3D Navier-Stokes equations for multi-phase flows using the Volume of Fluid (VOF) and Volume of Solid (VOS) models. The droplet formation is studied for different transient velocity conditions and mass rates. The numerical results show reasonable agreement with both analytical theory and experimenta

Quality Improvements by Integrating Development Processes

Software is an increasing and important part of many products and systems. Software, hardware, and system level components have been developed and produced following separate processes. However, in order to improve the quality of the final complex product, requirements and prospects for an automatic integrated process support are called for. Product data management (PDM) has focused on hardware pr

Bringing the College Inside

While other companies have a hard time reaching out to universities, leading university reach into Porsche to make substantial contributions to Porsche's innovation leadership. This is why and how Porsche manages to leverage university research in this unique way.

Plasma tumour necrosis factor-alpha and early carotid atherosclerosis in healthy middle-aged men

Aims Tumour necrosis factor-alpha (TNF-alpha) is a proinflammatory cytokine, which is implicated in some metabolic disorders and may play a role in the development of cardiovascular disease. We examined whether plasma TNF-alpha is related to established cardiovascular risk indicators, plasma levels of soluble cellular adhesion molecules and carotid artery intima-media thickness determined by ultra

Mechanisms behind the lipid-lowering effects of ACTH - Studies in different experimental models

Popular Abstract in Swedish Populärvetenskaplig sammanfattning Introduktion Adrenokortikotropiskt hormon (ACTH) stimulerar frisättningen av steroid¬hormoner, främst kortisol, från binjurarna. Kortisol är livsnödvändigt och finns alltid i blodet och förhöjs kraftigt vid stress. I början av 90-talet fann vår forskningsgrupp en koppling mellan ACTH och fettomsättningen som inte involverade steroidhAbstract Adrenocorticotrophic hormone (ACTH) has strong and direct lipid-lowering effects in man. All apoB-containing lipoproteins, i.e. VLDL, LDL, Lp(a), are reduced by 25-30%. In contrast, levels of HDL increase about 10%. In hepatic cell cultures, ACTH inhibits expression and secretion of apoB. In this thesis we corroborate that the reduced apoB synthesis, seen in hepatic cell systems, is als