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Background: Patients diagnosed with metastatic breast cancer have poor outcome with a median survival of approximately 2 years. While novel therapeutic options are urgently needed, the great majority of breast cancer research has focused on the primary tumor and less is known about metastatic breast cancer and the prognostic impact of the metastatic tumor microenvironment. Here we investigate the

Background: The COVID-19 pandemic has rapidly led to some of the most revolutionary changes in private and professional life around the world. While the extent and duration of these changes are not certain, they have already had a great impact on travel patterns. This is also the case in Sweden, despite its relatively liberal approach to restrictions, which relies on voluntary measures such as soc

Enlargements of distal airspaces can indicate pathological changes in the lung, but accessible and precise techniques able to measure these regions are lacking. Airspace Dimension Assessment with inhaled nanoparticles (AiDA) is a new method developed for in vivo measurement of distal airspace dimensions. The aim of this study was to benchmark the AiDA method against quantitative measurements of di

Through changes in climate and other environmental factors, alpine tundra ecosystems are subject to increased cover of erect shrubs, reduced predictability of rodent dynamics and changes in wild and domesticated herbivore densities. To predict the dynamics of these ecosystems, we need to understand how these simultaneous changes affect alpine vegetation. In the long term, vegetation dynamics may d

The fusion-evaporation reaction 28Si+40Ca at 122 MeV beam energy was used to populate excited states in the N=Z+1 nucleus 63Ga. With the combination of the Gammasphere spectrometer and the Microball CsI(Tl) charged-particle detector array, the level scheme of 63Ga was extended by more than a factor of two in terms of number of γ-ray transitions and excited states, excitation energy (Ex>30 MeV), an

A 27-year-old woman (gravida 2, para 1) was transported to the regional university hospital in gestational week (GW) 34 + 4 due to a three-day history of fever, abdominal pain and reduced foetal movements. She had developed a dry cough one day prior to the admission (Figure S1). The woman, was slightly overweight (BMI 27 kg/m2 ) but otherwise healthy. She had normal antenatal check-ups and an obst

Detta nummer av Svensk Teologisk Kvartalskrift är ett temanummer om praktisk teologi. Det innehåller en ledare, fyra artiklar och fem recensioner.

Ledaren i ett nummer av Svensk Teologisk Kvartalskrift med praktisk teologi som tema.

This article is the outcome of two research trips to the Jain caves at Ellora, the purpose of which was to photograph the best preserved murals found there, works of art that were largely undocumented in any available literature. The article documents and portrays the best preserved paintings in detail found on the walls and ceiling of one of the smaller caves belonging to the largest Jain cave coThis article is the outcome of two research trips to the Jain caves at Ellora, the purpose of which was to photograph the best preserved murals found there, works of art that were largely undocumented in any available literature. The article documents and portrays the best preserved paintings in detail found on the walls and ceiling of one of the smaller caves belonging to the largest Jain cave co

This article describes and discusses an ongoing change of case marking, NOM(inative) > OBL(ique), in certain predicates in Swedish (type “Then you can be I” > “Then you can be me”). This change has gone largely unnoticed hitherto. The discussion is based on a large-scale online survey, conducted in May 2016. It was tested whether the change relates to finiteness or to semantics. The results strong

This thesis presents the simulations of and experiments with the so-called CECOST burner. The CECOST burner is a gas turbine model combustor equipped with an axial swirler and placed in a laboratory for the lean premixed turbulent combustion of a range of fuels at atmospheric pressure. The operation with natural gas, methane, hydrogen-enriched methane and syngas from black-liquor gasification was

Background and aims: Histopathology is the gold standard for analysis of atherosclerotic plaques but has drawbacks due to the destructive nature of the method. Ex vivo MRI is a non-destructive method to image whole plaques. Our aim was to use quantitative high field ex vivo MRI to classify plaque components, with histology as gold standard.Methods: Surgically resected carotid plaques from 12 patie

Management of asymptomatic carotid disease continues to challenge medical practice and present evidence is often conflicting. Stroke is a significant burden in Public Health and 11% to 15% appear as first neurologic event associated with asymptomatic carotid stenosis. Randomized trials provided support for Guidelines and Recommendations to intervene on asymptomatic stenosis, but at a known cost of

Den första av två artiklar rörande det fängelse, den s k proban, som Lunds universitet hade under den tid lärosätet ägde egen jurisdiktion över anställda och studenter. Denna första del behandlar fenomenet med skol- och universitetsfängelser generellt samt Lunds universitets specifika sådana under 1600- och 1700-talen.

Subarctic forest-tundra ecotones dominated by mountain birch (Betula pubescens ssp. czerepanovii) are an important habitat for semi-domestic reindeer Rangifer tarandus. The seasonal timing of reindeer grazing may direct vegetation trajectories in these systems, because in the summer ranges, mountain birches are subjected to browsing, while in the winter ranges, reindeer feed on understorey vegetat