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Effectiveness of the BNT162b2 mRNA Vaccine Compared with Hybrid Immunity in Populations Prioritized and Non-Prioritized for COVID-19 Vaccination in 2021–2022 : A Naturalistic Case-Control Study in Sweden

The term hybrid immunity is used to denote the immunological status of vaccinated individuals with a history of natural infection. Reports of new SARS-CoV-2 variants of concern motivate continuous rethought and renewal of COVID-19 vaccination programs. We used a naturalistic case-control study design to compare the effectiveness of the BNT162b2 mRNA vaccine to hybrid immunity 180 days post-vaccina

The T-type calcium channel CaV3.2 regulates insulin secretion in the pancreatic β-cell

Voltage-gated Ca2+ (CaV) channel dysfunction leads to impaired glucose-stimulated insulin secretion in pancreatic β-cells and contributes to the development of type-2 diabetes (T2D). The role of the low-voltage gated T-type CaV channels in β-cells remains obscure. Here we have measured the global expression of T-type CaV3.2 channels in human islets and found that gene expression of CACNA1H, encodi

Play with a purpose: Intensive parenting, educational desires and shifting notions of childhood and learning in twenty-first century Singapore

This article examines how Singaporean parents negotiate complex expectations in relation to current reforms aimed at raising creative and problem-solving children. Based on ethnographic fieldwork, the article explores how ideas of brain-claiming, resilience, and natural exposure shape parenting practices around young children’s learning. The findings suggest that parents’ sentiments of uncertaintyThis article examines how Singaporean parents negotiate complex expectations in relation to current reforms aimed at raising creative and problem-solving children. Based on ethnographic fieldwork, the article explores how ideas of brain-claiming, resilience, and natural exposure shape parenting practices around young children’s learning. The findings suggest that parents’ sentiments of uncertainty

Components of gait in people with and without mild cognitive impairment

Background: Several objective gait parameters are associated with cognitive impairment, but there is limitedknowledge of gait models in people with mild cognitive impairment (MCI).Research question: How can 18 objective gait characteristics be used to define different components of gait inpeople with MCI (with suspected incipient neurocognitive disorder) and cognitively unimpaired people (CU),resp

Musiklärares arbete med bedömning och betygsättning : yttre och personliga omständigheter som påverkar praktiker samt möjliga subjektspositioner

I Sveriges grundskolor använder musiklärare en stor del av sin arbetstid till arbete som rör bedömning och betygsättning. Fem musiklärare har i denna studie intervjuats med syftet att ta reda på hur de konstruerar sina bedömnings- och betygsättningspraktiker genom att undersöka vilka omständigheter som inverkar på dessa. Studiens vetenskapsteoretiska förankring finns i socialkonstruktionismen; teaMusic teachers in Swedish compulsory schools spend much of their time with work concerning assessment and grading. In this study, five music teachers have been interviewed with the purpose of finding out how they construct their assessment and grading practices by inquiring into by what circumstances their practices are affected. The study’s theoretical foundation lies within social constructionis

Interactions with pain-related systems - Towards new electrical treatments for chronic pain

Background. Persistent intolerable pain is still an unsolved issue with a huge socioeconomic impact. To develop appropriate treatments, it is crucial to understand the complex mechanisms underlying pain and how they change during sustained pain stimuli or during pathological conditions. In particular, it is essential to clarify how the endogenous analgesic centres which are present in the brain, s

Educational desires, intensive parenting and shifting notions of childhood in twenty-first century Singapore

This paper explores educational desires, parenting and shifting notions of childhood in contemporary Singapore. Singapore’s education system is globally renowned for its high academic standards and for producing students who excel in international assessment tests and rankings. At the same time, there has been a shift of attention in education policy towards social-emotional competencies and well-This paper explores educational desires, parenting and shifting notions of childhood in contemporary Singapore. Singapore’s education system is globally renowned for its high academic standards and for producing students who excel in international assessment tests and rankings. At the same time, there has been a shift of attention in education policy towards social-emotional competencies and well-

Quantifying the influence of urban biotic and abiotic environmental factors on great tit nestling physiology

There is a long history of avian studies investigating the impacts of urbanization. While differences in several life-history traits have been documented, either between urban and rural populations or across generalized urbanization gradients, a detailed understanding of which specific environmental variables cause these phenotypic differences is still lacking. Here, we quantified several local en

Product destruction: Exploring unsustainable production-consumption systems and appropriate policy responses

The practice of product destruction, whereby retailers or manufacturers dispose of viable consumer products such as unsold goods or customer returns, is an extreme expression of the linearity of our current production-consumption system. This qualitative exploratory study aims to uncover why companies engage in this highly unsustainable and resource-inefficient behaviour and to explore the potenti

Taxonomy of the lichen family Teloschistaceae based on multigene phylogeny

The lichen family Teloschistaceae (Teloschistales, lichenized Ascomycota) included ten genera and ca 500 species prior to the molecular era (Kärnefelt 1989). Since then, molecular studies resulted in today's ca 112 genera and ca 1200 species (e.g., Fayyaz et al. 2022; Kondratyuk et al. 2022a, 2022b). New species and genera in the Teloschistaceae, based on recently discovered monophyletic branches,

Contributions to molecular phylogeny of lichens 4. New names in the Teloschistaceae

The new genus Kudratoviella for the former Caloplaca zeorina group having the highest level of bootstrap support in the phylogenetic tree of the Teloschistaceae, based on combined dataset of nrITS, 28S nrLSU DNA and 12S SSU mtDNA sequences, which does not belong to any other earlier proposed genera of the subfamily Xanthorioideae, is described. The genus Oceanoplaca Arup, Søchting et Bungartz founThe new genus Kudratoviella for the former Caloplaca zeorina group having the highest level of bootstrap support in the phylogenetic tree of the Teloschistaceae, based on combined dataset of nrITS, 28S nrLSU DNA and 12S SSU mtDNA sequences, which does not belong to any other earlier proposed genera of the subfamily Xanthorioideae, is described. The genus Oceanoplaca Arup, Søchting et Bungartz foun

New and noteworthy lichen-forming and lichenicolous fungi, 12

Seven species new to science are described, illustrated and compared with closely related taxa. Of them, one species, i.e.: Coppinsidea vernadskiensis S. Y. Kondr., T. O. Kondratiuk et I. Yu. Parnikoza is from the Argentine Islands, Western Maritime Antarctic Peninsula, Jacke lixia hosseussii S. Y. Kondr., L. Lőkös et J.-S. Hur, from South America (Argentina and Uruguay), Loekoeslaszloa reducta YoSeven species new to science are described, illustrated and compared with closely related taxa. Of them, one species, i.e.: Coppinsidea vernadskiensis S. Y. Kondr., T. O. Kondratiuk et I. Yu. Parnikoza is from the Argentine Islands, Western Maritime Antarctic Peninsula, Jacke lixia hosseussii S. Y. Kondr., L. Lőkös et J.-S. Hur, from South America (Argentina and Uruguay), Loekoeslaszloa reducta Yo

Quantitative properties of the creation and activation of a cell-intrinsic duration-encoding engram

The engram encoding the interval between the conditional stimulus (CS) and the unconditional stimulus (US) in eyeblink conditioning resides within a small population of cerebellar Purkinje cells. CSs activate this engram to produce a pause in the spontaneous firing rate of the cell, which times the CS-conditional blink. We developed a Bayesian algorithm that finds pause onsets and offsets in the r

Gender Transculturation : Navigating Market-Mediated Contesting Gender Ideologies in Consumer Acculturation

In this book, I advance the concept of gender transculturation to illustrate how migrant consumers navigate contesting gender ideologies in their host cultural marketplace. Taking a consumer cultural theoretical perspective, the study lies in the nexus of and unpacks an alternative understanding in the current research frontier of consumer acculturation, gender and ideologies. Acculturation of imm

What the latest science on climate change mitigation means for cities and urban areas

The Summary for Urban Policymakers (SUP) initiative provides a distillation of the IPCC reports into accessible and targeted summaries that can help inform action at city and regional scales. Volume I in the series, What the Latest Physical Science of Climate Change Means for Cities, identified the ways in which human-induced climate change is affecting every region of the world, and the cities an

Co-regulation of temperature and moisture in the irrigated agricultural ecosystem productivity

Agroecosystem photosynthesis is key to coping with global climate change. In farmland where human activities are highly involved, the interaction between environmental factors and their influences on gross primary productivity (GPP) are insufficiently understood. Particularly, the irrigation and mulching in water-saving agriculture can alter the crop responses to environmental change. Based on edd

Water use efficiency control for a maize field under mulched drip irrigation

Agricultural ecosystem water use efficiency (WUE) is an important indicator reflecting carbon-water coupling, but its control mechanisms in managed fields remain unclear. In order to reveal the influencing factors of WUE in the agricultural field under mulched drip irrigation (DM), we carried out the 8-year continuous observations in a maize field from Northwestern China. The structural equation m