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CD103+CD11b+ dendritic cells (DC) are the major migratory DC subset in the small intestine lamina propria (siLP) and their survival is dependent on the transcription factor interferon regulatory factor 4 (IRF4). Mice with a DC-specific deletion of irf4 (CD11c-cre.Irf4 mice) have reduced mucosal CD103+CD11b+ DC and altered T cell differentiation to protein antigen. The influence of CD103+CD11b+ DC

Background: Gorham-Stout disease (OMIM 123880) and generalized lymphatic anomaly are two rare disorders of lymphendothelial growth in which thoracic involvement with chylothorax is a feared complication. Currently it is believed that both disorders are prenatal malformations that progress slowly after birth. Several pharmaceuticals with antiproliferative properties, including interferon-α-2b, rapa

We provide necessary and sufficient structural conditions for multistationarity and oscillations in aggregate monotone systems, defined as the interconnection of stable monotone components. Our classification is based on the presence of exclusively positive or exclusively negative cycles in the system aggregate graph, whose nodes are the monotone subsystems. The results presented here scale up the

We consider the problem of tuning the output of a static plant whose model is unknown, under the only information that the input-output function is monotonic in each component or, more in general, that its Jacobian belongs to a known polytope of matrices. As a main result, we show that, if the polytope is robustly non-singular (or has full rank, in the non-square case), then a suitable tuning sche

Molecular titration is emerging as an important biochemical interaction mechanism within synthetic devices built with nucleic acids and the CRISPR/Cas system. We show that molecular titration in the context of feedback circuits is a suitable mechanism to enhance the emergence of oscillations and bistable behaviors. We consider biomolecular modules that can be inhibited or activated by input monome

The paper presents and analyses some nonlinear continuous-time dynamic models of social systems whose members, groups or individuals, may change partners and/or opponents at any time, according to a greedy criterion. The main structural properties of these models, which belong to the class of positive switching systems, are investigated with particular regard to the existence of solutions, their p

An experimental analysis of the fire behavior of stone wool composites with stainless steel and gypsum plasterboard linings was performed. The focus was to characterize the micro-scale behavior of stone wool, and identify the main processes occurring in stone wool composites when exposed to heat. Thermogravimetric analysis was applied to two different wools with varying densities and binder conten

Combination of right EGR rates with turbocharging has been identified as a promising way to increase the maximum load and efficiency of heavy duty spark-ignited natural gas engines. With stoichiometric conditions a three way catalyst can be used which means that regulated emissions can be kept at very low levels. However dilution limit is limited in these types of engines because of the lower burnCombination of right EGR rates with turbocharging has been identified as a promising way to increase the maximum load and efficiency of heavy duty spark-ignited natural gas engines. With stoichiometric conditions a three way catalyst can be used which means that regulated emissions can be kept at very low levels. However dilution limit is limited in these types of engines because of the lower burn

Endothelial progenitor cells (EPCs) contribute to neovasculogenesis and reendothelialization of damaged blood vessels to maintain the endothelium. Dysfunction of EPCs is implicated in the pathogenesis of vascular injury induced by homocysteine (Hcy). We aimed to investigate the role of Cyclin A in Hcy-induced EPCs dysfunction and explore its molecular mechanism. In this study, by treatment of EPCs

Assessment of neurologic prognosis after cardiac arrest. Updated recommendations from the Swedish CPR Council Expert Group European Resuscitation Council (ERC) issued updated guidelines for postresuscitation care in 2015. This paper provides updated Swedish recommendations for neurological prognostication of patients remaining unconscious after cardiac arrest (CA). The prognostication should be ba

During the transition from a wartime to a peacetime economy in the mid-1940s, Sweden experienced a heated debate on economic planning in which a number of Sweden’s leading economists were involved. In 1941, Ingvar Svennilson, a member of the so-called Stockholm school of economists, became the head of the Industrial Institute of Economic and Social Research, founded by Swedish industry. During the

The purpose of this article is (a) to review scholarly literature on entrepreneurship among Somalis in the United Kingdom and (b) through a field survey among Somali entrepreneurs in the UK assess if the prevailing image – derived from (a) – is valid or if some additional observations may alter the picture. Step (b) is accomplished through interviews with 36 Somalia-born entrepreneurs, most of the

Den somaliafödde företagaren är en i Sverige mindre vanlig uppenbarelse. Det beror knappast på att somalier i allmänhet skulle sakna ”företagaranda”. Det förhåller sig nämligen tvärtom. De flesta somalier i diasporan kommer från miljöer där någon i familjen eller släkten haft en butik, restaurang eller importfirma. Och i många länder där somaliska flyktingar de senaste årtiondena slagit sig ner ha

Artikeln presenterar tre aspekter av Gustaf Frödings verksamhet som teaterkritiker under åren 1888-1894: för det första hans recensioner i Karlstads-Tidningen av dramatiska arbeten som getts ut i bokform, för det andra hans signerade teaterrecensioner i Karlstads-Tidningen, och för det tredje osignerade teaterrecensioner i Karlstads-Tidningen som kan ha skrivits av Fröding.

Företagsekonomiska ämneskonferensen (FEKIS) Företagsekonomi i den urbana samhällsutvecklingenMalmö högskola 18-19 oktober 2017Katja Lindqvist och Ulrika WestrupInstitutionen för service management och tjänstevetenskap, Lunds universitetSamverkansforskning och forskning om samverkan – politik och praktikSamverkan har blivit det nya politiska mantrat. Samverkan krävs inom hela offentliga sektorn ida