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Establishment of an international database for genetic variants in esophageal cancer

The establishment of a database has been suggested in order to collect, organize, and distribute genetic information about esophageal cancer. The World Organization for Specialized Studies on Diseases of the Esophagus and the Human Variome Project will be in charge of a central database of information about esophageal cancer–related variations from publications, databases, and laboratories; in add

Energy security in a decarbonised transport sector: A scenario based analysis of Sweden's transport strategies

Previous research has shown that it is possible to decarbonise Sweden's road transport sector. This study develops a scenario based method and analyses the influence of external factors on energy security, focusing on passenger and freight transport. It does so by analysing the vulnerabilities and capabilities of five different climate mitigation strategies, investigating previous security scenariPrevious research has shown that it is possible to decarbonise Sweden's road transport sector. This study develops a scenario based method and analyses the influence of external factors on energy security, focusing on passenger and freight transport. It does so by analysing the vulnerabilities and capabilities of five different climate mitigation strategies, investigating previous security scenari

How to polarise all neutrons in one beam : A high performance polariser and neutron transport system

Polarised neutron beams are used in disciplines as diverse as magnetism,soft matter or biology. However, most of these applications often suffer from low flux also because the existing neutron polarising methods imply the filtering of one of the spin states, with a transmission of 50% at maximum. With the purpose of using all neutrons that are usually discarded, we propose a system that splits the

Splanchnic vein thrombosis in myeloproliferative neoplasms : Risk factors for recurrences in a cohort of 181 patients

We retrospectively studied 181 patients with polycythaemia vera (n=67), essential thrombocythaemia (n=67) or primary myelofibrosis (n=47), who presented a first episode of splanchnic vein thrombosis (SVT). Budd-Chiari syndrome (BCS) and portal vein thrombosis were diagnosed in 31 (17.1%) and 109 (60.3%) patients, respectively; isolated thrombosis of the mesenteric or splenic veins was detected in

Multi-Grid boron-10 detector for time-of-flight spectrometers in neutron scattering science

The Multi-Grid (MG) detector has been introduced at ILL and developed by a collaboration between ILL, ESS and Linkoping University. This detector design addresses the severely decreased availability of He3, in particular for neutron scattering instruments with large-area detectors, such as time-of-flight neutron spectrometers at ESS and other facilities. The MG detector is based on thin converter

Size-effects in indium gallium arsenide nanowire field-effect transistors

We fabricate and analyze InGaAs nanowire MOSFETs with channel widths down to 18 nm. Low-temperature measurements reveal quantized conductance due to subband splitting, a characteristic of 1D systems. We relate these features to device performance at room-temperature. In particular, the threshold voltage versus nanowire width is explained by direct observation of quantization of the first sub-band,

The use of the regenerating frog sciatic nerve for pharmacological studies of orthograde and retrograde axonal transport

The outgrowth region of the regenerating frog sciatic nerve shows an increased permeability for various drugs, which has been utilized for pharmacological studies of axonal transport. Six days after a bilateral crush lesion, the nerves, including the spinal ganglia, were incubated in a compartmented chamber. Orthograde transport was assessed from the proximodistal distribution and the accumulation

Regeneration in vitro of the adult frog sciatic sensory axons

The adult frog sciatic nerve offers several advantages as an in vitro model to study nerve regeneration. The nerve with the attached dorsal root ganglia can easily be isolated and incubated in a culture medium for several days. If the nerve is subjected to a crush immediately after dissection there is a delay of 3.4 days after which the sensory axons start to regenerate into the distal nerve stump

Primary triage nurses do not divert patients away from the emergency department at times of high in-hospital bed occupancy - a retrospective cohort study

Background: Emergency department (ED) overcrowding is frequently described in terms of input- throughput and output. In order to reduce ED input, a concept called primary triage has been introduced in several Swedish EDs. In short, primary triage means that a nurse separately evaluates patients who present in the Emergency Department (ED) and either refers them to primary care or discharges them h

Upregulation of cytosolic phospholipase A2 correlates with apoptosis in mouse superior cervical and dorsal root ganglia neurons

The involvement of cytosolic phospholipase A2 (cPLA2) in apoptosis of adult mouse superior cervical and dorsal root ganglia neurons has been investigated by the use of immunohistochemistry for cPLA2 and DNA nick-end labeling for apoptotic cells, respectively, cPLA2 immunoreactivity was strongly upregulated in neurons of both preparations during in vitro culturing. By double labeling it was unequiv

Effects of glial cell line-derived neurotrophic factor on axonal growth and apoptosis in adult mammalian sensory neurons in vitro

The effects of glial cell line-derived neurotrophic factor on axonal outgrowth and apoptosis were studied in vitro using explanted dorsal root ganglia-peripheral nerve preparations of adult mice. In gels of matrigel or collagen type 1, glial cell line-derived neurotrophic factor increased both the numbers and lengths of axons growing out of explanted preparations, although less effectively than ne

Bodily Education in Modernist Culture - Freedom and Commodification

The actor’s practice and bodily training during the twentieth century are specifically related not only to different bodily techniques, but also to language, modern society, and the concept of freedom. Nationalism, anti-intellectualism, bodily and vitalistic purism, and a sceptical distance from the modern project at the beginning of the twentieth century serve as a starting point for a discussionThe actor’s practice and bodily training during the twentieth century are specifically related not only to different bodily techniques, but also to language, modern society, and the concept of freedom. Nationalism, anti-intellectualism, bodily and vitalistic purism, and a sceptical distance from the modern project at the beginning of the twentieth century serve as a starting point for a discussion

Neutron optics concept for the materials engineering diffractometer at the ESS

The Beamline for European Materials Engineering Research (BEER) has been recently proposed to be built at the European Spallation Source (ESS). The presented concept of neutron delivery optics for this instrument addresses the problems of bi-spectral beam extraction from a small moderator, optimization of neutron guides profile for long-range neutron transport and focusing at the sample under vari

BEER-The Beamline for European Materials Engineering Research at the ESS

The Beamline for European Materials Engineering Research (BEER) will be built at the European Spallation Source (ESS). The diffractometer utilizes the high brilliance of the long-pulse neutron source and offers high instrument flexibility. It includes a novel chopper technique that extracts several short pulses out of the long pulse, leading to substantial intensity gain of up to an order of magni

Filling the Gap – Improving Awareness and Practice in Hyponatraemia and the Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH) in the Older Patient : A European Consensus View

Introduction: Causes of hyponatraemia in older patients are multivariate and in the case of SIADH may often be drug induced. Diagnostic and treatment algorithms are unclear for this important age group. Methods: The author group identified 6 broad themes for consensus and formulated 42 separate consensus statements within these 6 themes. Statements were then circulated to geriatricians, general p

Review of remediation practices regarding cadmium-enriched farmland soil with particular reference to China

Cadmium-enrichment of farmland soil greatly threatens the sustainable use of soil resources and the safe cultivation of grain. This review paper briefly introduces the status of farmland soil as well as grain, which are both often polluted by cadmium (Cd) in China, and illustrates the major sources of Cd contaminants in farmland soil. In order to meet soil environmental quality standards and farml

Internet of Things and Business Models

Understanding implications on firm performance from the emergence of Internet of Things (IoT) is critical in order for firms to make rational decisions regarding business model configurations and investments in IoT. The transition between the current state and widespread adoption and diffusion of IoT is expected to be complex, and standardization is one of multiple barriers discussed in research r