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Body-focused repetitive behavior disorders, including trichotillomania (hair-pulling disorder) and excoriation (skin picking) disorder, typically emerge in early adolescence, but little is known about the clinical characteristics and treatment outcomes of these disorders in young people, particularly in real-world clinical settings. Participants were 63 children and adolescents (51 girls; age rang

In many democratic societies, research has identified an increase in animosity between supporters of different political parties. While this phenomenon has been extensively examined among the general public, less research has explored the role of political elites in contributing to partisan hostility. This study aims to fill this research gap by analyzing instances where members of parliament (MPs

Introduction: Ovarian cancer is the leading cause of death among women with gynecological cancer, and novel treatment options are urgently needed. Extracellular vesicles (EVs), including exosomes, may be one of the most promising therapeutic tools for various diseases. In this study, we aimed to investigate the therapeutic effects of adipose-derived stem cell-derived EVs (ADSC-EVs) on ovarian canc

Congenital diaphragmatic hernia (CDH) is a severe birth defect frequently associated with pulmonary hypoplasia, pulmonary hypertension, and heart failure. Since amniotic fluid comprises proteins of both fetal and maternal origin, its analysis could provide insights on mechanisms underlying CDH and provide biomarkers for early diagnosis, severity of pulmonary changes and treatment response. The stu

Background. National as well as international Parkinson's disease (PD) treatment guidelines are available to guide clinicians. Previous research has shown that nonmotor symptoms (NMS) are pronounced in late-stage PD and has suggested that current treatment is insufficient and could be improved. Objectives. The aim of this study was to investigate to which degree the national and international trea

How was the scope of nuclear weapons policy change immediately after the Cold War determined? Nuclear learning and worst-case thinking are common but not satisfactory answers. On the basis of primary sources in multiple languages, we posit that a particular temporalization of nuclear events in the beginning of the 1990s took place: nonproliferation timescaping. The Iraqi case of opaque proliferati

Performative and philosophical approaches to contemporary theatre and performance art.Book based on my PhD.

Social workers often fail to engage fathers in child protection investigations (CPIs), especially when they involve domestic abuse (DA) by fathers. The aim of this study is to examine the strategies used by social workers to achieve cooperation with fathers in CPIs that involve the father being suspected of DA against the child's mother. With the use of qualitative methods, we conducted 31 semi-st

Characterising the interaction between cationic ionisable lipids (CIL) and nucleic acids (NAs) is key to understanding the process of RNA lipid nanoparticle (LNP) formation and release of NAs from LNPs. Here, we have used different surface techniques to reveal the effect of pH and NA type on the interaction with a model system of DOPC and the CIL DLin-MC3-DMA (MC3). At only 5% MC3, differences in

We present a novel class of minimax optimal control problems with positive dynamics, linear objective function and homogeneous constraints. The proposed problem class can be analyzed with dynamic programming and an explicit solution to the Bellman equation can be obtained, revealing that the optimal control policy (among all possible policies) is linear. This policy can in turn be computed through

Factors behind intraspecific variation in sensitivity to pathogens remain poorly understood. We investigated how geographical origin in two North European amphibians affects tolerance to infection by the chytrid fungus Batrachochytrium dendrobatidis (Bd), a generalist pathogen which has caused amphibian population declines worldwide. We exposed newly metamorphosed individuals of moor frog Rana arv

Aims: Infections are proposed risk factors for type 1 diabetes in children. We examined whether a diagnosis of infectious disease also confers an increased risk of latent autoimmune diabetes in adults (LADA). Materials and methods: We used data from a population-based Swedish case-control study with incident cases of LADA (n = 597) and matched controls (n = 2386). The history of infectious disease