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Six different cysteine proteinase inhibitors (cystatins) were isolated from human urine and characterized. Five of them......
Introduction: After surgery for distal femur fractures in elderly patients, weight-bearing is commonly restricted. Immediate non-restrictive weight-bearing might have beneficial effects. There are no randomized studies on the topic. The purpose of this study was to compare the functional outcome between immediate full weight-bearing (FWB) as tolerated and partial weight-bearing (PWB) during the fi
Within the grand sandstone quarries of Gebel el-Silsila is a vast amount of unique symbolic representations; stylized iconographic and pseudo-scripted signs and marks that to some extent signify deities and their protection against demons, evil and mishaps. Like written protective formulae, these marks were placed within the quarries to symbolically safe-keep the quarry workers, and for expressing
ObjectiveMost research on patient experiences of rheumatoid arthritis (RA) care is performed with patients who have established RA and less often with patients with early RA. Experiences of and expectations about health care may change over time, which is why the aim was to explore patients’ perceptions of person-centered care (PCC) early in the RA disease course.MethodsThirty-one patients with ea
This dissertation studies the relationship between emotions and the everday application of apartheid in South Africa between 1948 and 1990. Histories of apartheid have long been politics-driven, focusing on the rise and fall of the regime with its reception being studied primarily through the lens of the popular struggle that, in part, led to apartheid’s downfall. Thus, the lived experience and re
Rationale & Objective: A healthy lifestyle promotes cardiovascular health and reduces cardiac-related mortality in the general population, but its benefits for people receiving maintenance hemodialysis are uncertain. Study Design: Prospective cohort study. Setting & Participants: 5,483 of 9,757 consecutive adults receiving maintenance hemodialysis (January 2014 to June 2017, median dialysi
Stämmer föreställningen att John Rawls rättviseteori i A Theory of Justice är en empiriskt oförankrad analytisk konstruktion? Halldenius hävdar att den inte gör det. Rawls yttersta bevekelsegrunder var etiska, hans etik vardaglig och psykologisk och hans ambition att analysera människan i sitt samhälleliga sammanhang. Rättviseprincipernas universalitet till trots är rättvisans fråga ändå alltid en
Background: Accurate markers for prostate cancer (PC) risk stratification could aid decision-making for initial management strategies. The 4Kscore has an undefined role in predicting outcomes after radical prostatectomy (RP). Methods: We included 1476 patients with 4Kscore measured prior to RP at two institutions. The 4Kscore was assessed for prediction of adverse pathology at RP and biochemical r
How might a liberal democratic community best regulate human genetic engineering? Relevant debates widely deploy the usually undefined term “human dignity.” Its indeterminacy in meaning and use renders it useless as a guiding principle. In this article, I reject the human genome as somehow invested with a moral status, a position I call “genetic essentialism.” I explain why a critique of genetic e
This chapter proceeds from the contention that analysing power, oppression, and dominance together – particularly accounting for the experience of being subjected to oppression and dominance in a context of power – reveals deficiencies in what is here referred to as the standard view of what power is. On the standard view, “power” is a purposive capacity concept about what some people do or can do
Republican political theory, with its commitment to a political and personal conception of freedom in terms of the absence of domination, has the potential to revitalize how we think about human rights. From a republican perspective, the aims of the politics of human rights are—in negative terms—to end exploitation, vulnerability, and precarity and—in positive terms—to establish a society of equal
Introduction: Harboring two copies of the apolipoprotein E (APOE) ε2 allele strongly protects against Alzheimer's disease (AD). However, the effect of this genotype on gray matter (GM) volume in cognitively unimpaired individuals has not yet been described. Methods: Multicenter brain magnetic resonance images (MRIs) from cognitively unimpaired ε2 homozygotes were matched (1:1) against all other AP
This paper investigates the drivers for, and implementation of, digital transformation projects and organizational change initiatives in 20 companies in the UK. The study follows on previous research based on the Socio-Technical Toolbox [STT], specifically focusing on the activity analysis and employees’ experience and participation in the change initiative or digital transformation project.
Annelien de Dijn’s Freedom: An Unruly History is a rich and thought-provoking work in intellectual history, tracing thinking and debating about political freedom in the West from ancient Greece to our own times. The ancient notion of freedom as self-government (what Quentin Skinner calls neo-roman liberty) is referred to as the ‘democratic conception’. The argument is that this conception survived
Red cell distribution width (RDW) is a measure of the variability of erythrocyte volumes. RDW has been associated with incidence of cardiovascular diseases. However, the underlying mechanisms for the increased cardiovascular risk are still unclear. This study aimed to examine associations of RDW and coronary atherosclerosis in the general population. Computed tomography was performed and RDW was m
Background: The second stage of labour is generally considered as an intensive part of labour. Despite this, knowledge about women's experiences of the second stage of labour is scant. Aim: To explore experiences of the second stage of labour in women with spontaneous vaginal birth. Methods: This is a qualitative study where twenty-one women with a spontaneous birth at term, were interviewed four
Inom den moderna universitetsvärlden är filosofi inte en brett utforskande intellektuell verksamhet utan ett “ämne”, en “disciplin”, med interna normer och traditioner för vad man gör, hur man gör det och vad som är ett filosofiskt problem. Hur filosofi som akademisk disciplin förhåller sig till andra discipliner är en stor fråga, men delvis kan den illustreras av hur det är att som filosof verka
