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MIRD Pamphlet No. 23: Quantitative SPECT for Patient-Specific 3-Dimensional Dosimetry in Internal Radionuclide Therapy

In internal radionuclide therapy, a growing interest in voxel-level estimates of tissue-absorbed dose has been driven by the desire to report radiobiologic quantities that account for the biologic consequences of both spatial and temporal nonuniformities in these dose estimates. This report presents an overview of 3-dimensional SPECT methods and requirements for internal dosimetry at both regional

The Development of Grammar : Language Acquisition and Diachronic Change. In honor of Jürgen M. Meisel

This volume focuses on different aspects of language development. The contributions are concerned with similarities and differences between first and second language acquisition, the acquisition of sentence structure and functional categories, cross-linguistic influence in bilingual first language acquisition as well as the relation between language acquisition, language contact and diachronic cha

Political institutions and their historical dynamics.

Traditionally, political scientists define political institutions deductively. This approach may prevent from discovery of existing institutions beyond the definitions. Here, a principal component analysis was used for an inductive extraction of dimensions in Polity IV data on the political institutions of all nations in the world the last two centuries. Three dimensions of institutions were revea

Mutations in the gene encoding the synaptic scaffolding protein SHANK3 are associated with autism spectrum disorders

SHANK3 (also known as ProSAP2) regulates the structural organization of dendritic spines and is a binding partner of neuroligins; genes encoding neuroligins are mutated in autism and Asperger syndrome. Here, we report that a mutation of a single copy of SHANK3 on chromosome 22q13 can result in language and/or social communication disorders. These mutations concern only a small number of individual

Signal Characterization of Atrial Arrhythmias using the Surface ECG

This doctoral thesis is comprised of five parts which deal with different signal processing problems in ECG-based characterization of atrial arrhythmias. Such characterization requires that the ventricular activity has first been cancelled in the ECG. In Part I, a new method for cancellation of the QRST complexes in recordings with atrial fibrillation is presented. The method is based on a spatiot

A linear algebra approach to minimal convolutional encoders

The authors review the work of G.D. Forney, Jr., on the algebraic structure of convolutional encoders upon which some new results regarding minimal convolutional encoders rest. An example is given of a basic convolutional encoding matrix whose number of abstract states is minimal over all equivalent encoding matrices. However, this encoding matrix can be realized with a minimal number of memory el

Lifetime measurements on the c '(1)(4)Sigma(+)(u), v=0, 1 and 2 states of molecular nitrogen

Excited state lifetimes of c(4)('1)Sigma (+)(u), upsilon = 0-2 states of molecular nitrogen have been determined in a laboratory investigation using a picosecond XUV laser in a pump-probe configuration. For c(4)('1)Sigma (+)(u) upsilon = 0 the lifetime is tau = 740 +/- 50 ps, for the lowest rotational states. For higher rotational states a gradual shift towards tau = 495 ps is found in agreement w

Rapid short-duration hypothermia with cold saline and endovascular cooling before reperfusion reduces microvascular obstruction and myocardial infarct size.

BACKGROUND: The aim of this study was to evaluate the combination of a rapid intravenous infusion of cold saline and endovascular hypothermia in a closed chest pig infarct model. METHODS: Pigs were randomized to pre-reperfusion hypothermia (n = 7), post-reperfusion hypothermia (n = 7) or normothermia (n = 5). A percutaneous coronary intervention balloon was inflated in the left anterior descending