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Optical Microrheology of Protein Solutions Using Tailored Nanoparticles

This work represents a critical re-examination of the application of dynamic light scattering (DLS)–based tracer particle microrheology to measure the zero shear viscosity of aqueous solutions of different proteins up to very high concentrations. It is demonstrated that a combination of surface-functionalized tracer particles, the use of the so-called 3D-DLS technique, and carefully chosen paramet

Nätkritiken utmanar censuren

På kort tid har Kina fått över 300 miljoner mikro­bloggare. På nätet sprids förutom skvaller och rykten även skarp kritik mot kommunistpartiet. Den kinesiska staten har fått en utmanare i kampen om informationen.

När karriären krackelerar? : En studie om hur unga journalister tänker kring situationen på arbetsmarknaden

Den här uppsatsen låter sex unga journalister komma till tals med avseende på hur de tänker kring förhållandena på arbetsmarknaden. Syftet är att med hjälp av en kvalitativ intervjustudie belysa hur unga journalister tänker kring sin karriär, framtid och livet vid sidan av yrket.Arbetsgivarna inom mediebranschen tillhör dem som i störst utsträckning kringgår lagen om anställningsskydd (LAS). Det i

Nonlinear dynamics in agricultural systems in Chad

Changes to agricultural systems in Sub-Saharan Africa are subject to a wide range of drivers, often resulting in rapid and nonlinear dynamics. Such dynamics are however rarely recognized in studies of trends and drivers, which usually rely on assumptions of gradual progressions, and often using highly aggregated data. This paper addresses this lack of recognition and understanding of nonlinear pro

Quinoline-galactose hybrids bind selectively with high affinity to a galectin-8 N-terminal domain

Quinolines, indolizines, and coumarins are well known structural elements in many biologically active molecules. In this report, we have developed straightforward methods to incorporate quinoline, indolizine, and coumarin structures into galactoside derivatives under robust reaction conditions for the discovery of glycomimetic inhibitors of the galectin family of proteins that are involved in immu

Older people's occupations. A life with and without work. : A life with and without work

Introduction: The demographic changes with population ageing and a rapidly growing share of very old peoplewill put an increasing pressure on the health and social care system. In order to both restrict early retirement and force people to extend their working life reforms are changing pension systems in many European countries. Besides that older people have to extend their working life it is imp

Research Data Management from planning to analysis: A case study of the NanoMAX beamline station at MAX IV Laboratory

The report summarises a small case study in which two research groups were interviewed and observed as they were planning, conducting and analysing experiments at MAX IV Laboratory.The aim of the study was to identify the current research data management practices of the scientists, and to connect this to how these practices are supported by MAX IV.The report summarises a small case study in which two research groups were interviewed and observed as they were planning, conducting and analysing experiments at MAX IV Laboratory.The aim of the study was to identify the current research data management practices of the scientists, and to connect this to how these practices are supported by MAX IV.

From conflict to compromise: The importance of mediation in Swedish work stoppages 1907-1927

Institutions for prevention and resolution of industrial conflicts were introduced all over the world in the early twentieth century. We use a new dataset of geocoded strikes and lockouts to analyze the impact of mediation on conflict outcomes in Sweden for the period 1907–1927. Causality is identified by using the distance from the mediator’s place of residence to the conflict as an instrument. D

Patient-reported and performance-based measures of walking in mild–moderate Parkinson's disease

Background: Knowledge of the relationships between patient-reported and performance-based walking measures in Parkinson's disease (PD) should inform clinical decision-making. The Walk-12G reliably captures perceived walking difficulties but has not been compared to performance-based walking in laboratory or free-living settings or across different groups. Objectives: To investigate the relationshi

WNT5A as a therapeutic target in breast cancer

Despite the clinical development of novel adjuvant and neoadjuvant chemotherapeutic drugs, metastatic breast cancer is one of the leading causes of cancer-related death among women. The present review focuses on the relevance, mechanisms, and therapeutic potential of targeting WNT5A as a future anti-metastatic treatment strategy for breast cancer patients by restoring WNT5A signaling as an innovat

Association of IgE-Mediated Allergy with Risk of Complicated Appendicitis in a Pediatric Population

Importance: Childhood appendicitis is commonly complicated by gangrene and perforation, yet the causes of complicated appendicitis and how to avoid it remain unknown. Objective: To investigate whether children with IgE-mediated allergy have a lower risk of complicated appendicitis. Design, Setting, and Participants: This retrospective cohort study included all consecutive patients younger than 15

A new professional landscape: Entangled institutional logics in two Swedish welfare professions

Previous research has made three parallel but incompatible observations on the contemporary development of welfare professions: loss of professional autonomy, hybridization, and maintained autonomy. Yet, research providing contextual understanding of the simultaneous occurrence of these three observations is lacking. The aim of this theoretical paper is to identify and explain seemingly contradict

Poly(ε-caprolactone)/cellulose nanocrystal nanocomposite mechanical reinforcement and morphology : the role of nanocrystal pre-dispersion

Cellulose nanocrystal (CNC) incorporation in polymeric matrices is an environmentally friendly approach to mechanical reinforcement. In general, significant mechanical reinforcement can only be achieved by means of good CNC dispersion at random orientation. These primary characteristics are even more relevant for the preparation of nanocomposites based on hydrophobic matrices, such as poly(ε-capro

A System Dynamics Assessment of the Supply of Molybdenum and Rhenium Used for Super-alloys and Specialty Steels, Using the WORLD6 Model

The extraction, supply, market price and recycling of the metals molybdenum and rhenium were modelled using an integrated system dynamics model. The resource estimates made here resulted in significantly larger estimates than earlier studies for molybdenum. Present molybdenum resources are about 75–80 million ton and about 7 million ton has been mined to date. The ultimately recoverable resources

Numerical study on thermal performance of non-uniform flow channel designs for cooling plates of PEM fuel cells

Due to the limited cooling capacity of air, large-scale proton exchange membrane (PEM) fuel cell stacks are generally cooled by liquid cooling where liquid water is circulated through the flow channels of cooling plates. Effective cooling is essential for the stability, durability, and performance of PEM fuel cells. In this study, cooling plates with conventional straight channel and novel non-uni

Building the Cape of Good Hope Panel

To study the intergenerational dynamics of productivity, social mobility and demographic change of any contemporary society is a challenge. To do this for a pre-industrial society at the southern tip of Africa seems almost impossible. Yet this is the purpose of the Cape of Good Hope Panel, an annual panel data set–still under construction–of Cape Colony settler tax records over almost two centurie