Proteins evolve under a myriad of biophysical selection pressures that collectively control the patterns of amino acid substitutions. These evolutionary pressures are sufficiently consistent over time and across protein families to produce substitution patterns, summarized in global amino acid substitution matrices such as BLOSUM, JTT, WAG, and LG, which can be used to successfully detect homologs

Microalgal range expansions are increasing in frequency and magnitude but generally remain unnoticed until mass development occurs. Gonyostomum semen is a freshwater raphidophyte that causes nuisance blooms in lakes and has recently expanded its distribution across Europe. G. semen was considered to mainly occur in humic lakes in the boreal region but is now found in high density also in other fre

Low-lying states of Cd-98 have been populated by the two-nucleon removal reaction (In-100, Cd-98+gamma) and studied using in-beam gamma-ray spectroscopy at the Radioactive Isotope Beam Factory at RIKEN. Two new gamma transitions were identified and assigned as decays from a previously unknown state. This state is suggested to be based on a pi 1g(/9/2)(-1)2p(1/2)(-2) configuration with J(pi) = 5(-)

In many animal phyla, eyes are small and provide only low-resolution vision for general orientation in the environment. Because these primitive eyes rarely have a defined image plane, traditional visual-optics principles cannot be applied. To assess the functional capacity of such eyes we have developed modelling principles based on ray tracing in 3D reconstructions of eye morphology, where refrac

The most common acoustical treatment of public rooms, such as schools, offices, and healthcare premises, is a suspended absorbent ceiling. The non-uniform distribution of the absorbent material, as well as the influence of sound-scattering objects such as furniture or other interior equipment, has to be taken into account when calculating room acoustic parameters. This requires additional informat

Assessing the optimal placement and design of a large‐scale high temperature energy storage system in crystalline bedrock is a challenging task. This study applies and evaluates various methods and strategies for pre‐site investigation for a potential high temperature borehole thermal energy storage (HT‐BTES) system at Linköping in Sweden. The storage is required to shift approximately 70 GWh of e

Cholinergic pesticides, such as the neonicotinoid imidacloprid, are the most important insecticides used for plant protection worldwide. In recent decades, concerns have been raised about side effects on non-target insect species, including altered foraging behavior and navigation. Although pollinators rely on visual cues to forage and navigate their environment, the effects of neonicotinoids on v

The Practice of Everyday Life (de Certeau M (1984) The Practice of Everyday Life. Berkeley, CA: University of California Press) has become a canonical text in urban studies, with de Certeau’s idea of tactics having been widely deployed to understand and theorise the everyday. Tactics of resistance were contrasted with the strategies of the powerful, but the ways in which these strategies are opera

Background: The COVID-19 pandemic has been suspected to increase mental health problems, but also to possibly lead to a decreased treatment seeking, for example due to fear of attending hospital. Early findings demonstrate decreased treatment seeking for mental health, which may differ across diagnostic groups. This study aimed to examine treatment uptake at a general psychiatry emergency unit and

This paper reflects on the ongoing debate between theory and practice in planning, using the example of South Africa. Based on survey responses, it discusses how planning education in South Africa is perceived to prepare students for practice. While we acknowledge that the majority of respondents view their planning education positively, the results reveal challenges regarding the practical applica

This paper examines the bus rapid transit (BRT) legacies of mega sporting events (MSEs) held in the Global South cities of Cape Town and Rio de Janeiro. It discusses the extent to which these transport systems have been operationally sustainable, post-MSE; in other words, their ability to be maintained at a certain rate or level and hence their ability to act as public good as planned and accordin

This paper explores the role of ICTs (Information and Communication Technologies) in rural, marginalised communities. We explore Feenberg’s concept of technical agency in order to understand the ways in which technological capacity might contribute to community development. We discuss three conditions of technical agency as outlined by Feenberg; power, knowledge and appropriate occasion. We consid

The role of informality in African citizens’ everyday survival reflects the strategies and attitudes of citizens towards state plans and policies. This chapter dissociates the discussion of temporary urbanism from its typical Global North perspective to explore how this concept plays out in a Southern context, namely Sub-Saharan Africa (SSA). We look at the relationships between temporary urban set

Importance: Disrupted sleep commonly occurs with progressing neurodegenerative disease. Large, well-characterized neuroimaging studies of cognitively unimpaired adults are warranted to clarify the magnitude and onset of the association between sleep and emerging β-amyloid (Aβ) pathology. Objective: To evaluate the associations between daytime and nighttime sleep duration with regional Aβ pathology