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Elective Testicular Biopsy at the End of Maintenance Treatment for Acute Lymphoblastic Leukemia. A Prospective Study

Open testicular wedge biopsy has electively been performed prior to completion of maintenance therapy for acute lymphoblastic leukemia. 25 boys during 6 years were included in this prospective study. Three boys developed testicular enlargement while on maintenance therapy and biopsies confirmed testicular leukemia. The remaining 22 boys were biopsied at termination of maintenance therapy. Occult t

The Social Capability Index and Income Convergence

Domestic social capabilities are a set of national characteristics for understanding why some countries grow faster than others. Yet there is no clear agreement on the main characteristics of these capabilities and therefore they have been neglected in the income convergence debate. The paper presents an index for revisiting the role of social capabilities in this debate. A relatively socially adv

Political battlefields : How within-firm goal conflict influences between-firm collaboration

In this paper, we inductively explore how within-firm goal conflict influences inter-firm collaboration over time. Based on our findings, we challenge current theorizing on collaborative dynamics in inter-organizational relationships, positioning firms as polilithic entities, where within-firm goal conflict can spur complex and unexpected between-firm collaborative processes and outcomes.

Developing a tool for self-assessment of IT process maturity : A design science research initiative

Today's IT organizations must ensure that IT services are aligned to business needs and actively support ongoing business processes. This means that internal IT service management processes are under constant improvement. However, to be able to know if the IT service provision develops in the right direction, there is a need to perform some kind of self-assessment of IT process maturity. In this p

National Parliaments and Political Control of EU Competences

It is clear that the formal inclusion of the national parliament as a political actor within the EU decision-making process has been one of the most important innovations of the Lisbon Treaty.Their role, however, remains controversial. It is on the one hand disputed whether national parliaments enjoy sufficient powers to tame'competence creep’. On the other hand, it is contested to what extent it

Photonic Monitoring of Atmospheric and Aquatic Fauna

Flying insects are of utmost importance in ecology and for human living conditions. Certain species serve as indispensable pollinators to ensure the availability of food stuffs, while others are dangerous vectors for spreading deadly diseases, such as malaria. Agricultural pests reduce the yield of crops, and their abatement through pesticides cause many additional problems. Birds and bats are fre

The host defense peptide LL-37 triggers release of nucleic acids from human mast cells

The human host defense peptide LL-37 possesses antimicrobial activity but also affects host cell function and viability. Mast cells are involved in innate immunity but no data have been presented on effects of LL-37 on human mast cell viability and export of nucleic acids. Here, we demonstrated by immunofluorescence microscopy that synthesized LL-37 was internalized by human LAD2 mast cells and de

Why marginalized groups struggle to leverage digital activism

Digital activism, political activism mediated by digital technologies, offers the promise of increased visibility and political power for marginalized groups. Yet, this has not been the case outside of a few exceptions such as Black Lives Matter. This paper offers theoretical, conceptual critical research that explores why successful digital activism may elude marginalized groups. We ask why many

Understanding GaAs Nanowire Growth in the Ag-Au Seed Materials System

The integration of III-V semiconductors with Si in device fabrication is facilitated by the use of nanoscale structures such as nanowires. Nanowires are predominantly grown using Au seed particles; however, the seed material is known to affect the nanowire growth and properties. Here we present growth of GaAs nanowires using three different seed particle materials: Au, Ag, and a AgAu alloy. By com

Governing interdisciplinary cooperation in Centers of Excellence

In the past years Centers of Excellence (CoE) has risen to prominence as a funding instrument in science. The idea is that by focusing resources, people and attention within a center environment, and over a substantial time span, excellence in science can be promoted. Similarly, interdisciplinarity is often seen as an enabling condition or even necessary for frontier research. This article builds

Prognostic significance of noncardiac syncope in the general population : A systematic review and meta-analysis

Introduction: Cardiac syncope heralds significantly higher mortality compared with syncope due to noncardiac causes or unknown etiology, commonly considered a benign event. A few epidemiologic studies have examined the outcome of noncardiac/unexplained syncope comparing individuals with and without syncope, but with controversial results. We performed a systematic review and meta-analysis to clari

Functional analyses of rare genetic variants in complement component C9 identified in patients with age-related macular degeneration

Age-related macular degeneration (AMD) is a progressive disease of the central retina and the leading cause of irreversible vision loss in the western world. The involvement of abnormal complement activation in AMD has been suggested by association of variants in genes encoding complement proteins with disease development. A low-frequency variant (p.P167S) in the complement component C9 (C9) gene

Dimensions and Interactions of Large T-Cell Surface Proteins

The first step of the adaptive immune response involves the interaction of T cells that express T-cell receptors (TCRs) with peptide-loaded major histocompatibility complexes expressed by antigen-presenting cells (APCs). Exactly how this leads to activation of the TCR and to downstream signaling is uncertain, however. Recent findings suggest that one of the key events is the exclusion of the large

Effect of material parameter variability on vibroacoustic response in wood floors

The use of wood as construction material in multi-story buildings increased in Europe during the last decades. Wood buildings are more sensitive to dynamic loading compared to conventional concrete buildings, especially in terms of vibroacoustic comfort. Furthermore, it is more difficult to predict the accurate response due to dynamic loading for wood buildings. This is due to factors such as a co

Den botaniska skattkammaren – en digital svensk flora blir till

The newly developed website ’Den botaniska skattkammaren’ [The botanic treasury; www.botskatt.se] is presented. It is intended to be gradually filled with miscellaneous information about vascular plant taxa found in, or expected to be found in Swedish nature (i.e. including all kinds of ephemerals and garden escapes). The material included will partly be newly produced, partly reproduced with permThe newly developed website ’Den botaniska skattkammaren’ [The botanic treasury; www.botskatt.se] is presented. It is intended to be gradually filled with miscellaneous information about vascular plant taxa found in, or expected to be found in Swedish nature (i.e. including all kinds of ephemerals and garden escapes). The material included will partly be newly produced, partly reproduced with perm

Simulated Dose Reduction for Abdominal CT With Filtered Back Projection Technique: Effect on Liver Lesion Detection and Characterization

OBJECTIVE. Previous studies have shown the possibility to reduce radiation dose in abdominal CT by 25–50% without negatively affecting detection of liver lesions. How radiation dose reduction affects characterization of liver metastases is not as well known. The objective of this study was to investigate how different levels of simulated dose reduction affect the detection and characterization of

Brexit: A Note on the EU's Interlegality

This study argues that Brexit is as much an internal UK crisis of law, identity politics and democracy as it is the EU crisis of integration. Does Brexit bring us a new insight into how the legal order of the EU and its Member States are interrelated? Does it throw a new light on the EU law’s ability to produce a sense of collective European identity and solidarity which transcends national borderThis study argues that Brexit is as much an internal UK crisis of law, identity politics and democracy as it is the EU crisis of integration. Does Brexit bring us a new insight into how the legal order of the EU and its Member States are interrelated? Does it throw a new light on the EU law’s ability to produce a sense of collective European identity and solidarity which transcends national border

Combined use of iteration, quadratic interpolation and an extra kernel forhigh-resolution 2D particle tracking : A first evaluation

A novel 2D particle tracking method, that uses 1) iteration, 2) fastquadratic sub-pixel estimation (with only 28 multiplications per movement), and3) a previous kernel, has been evaluated and compared with a full-searchblock-matching method. The comparison with high-frequency ultrasound data (40MHz) was conducted in silico and on phantoms, which comprised lateral, diagonal,and ellipsoidal movement