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Control of hypercapnia and mortality in home mechanical ventilation : the population-based DISCOVERY study

Background Studies on the survival of patients with home mechanical ventilation (HMV) are sparse. We aimed to analyse the impact of controlled hypercapnia on survival over 27 years among patients with HMV in Sweden. Study design and methods Population-based cohort study of adult patients starting HMV in the Swedish Registry for Respiratory Failure (Swedevox) during 1996–2022 cross-linked with the

The Scale and Extent of Political Economies of the Middle Bronze Age Jazīrah and the Bilād al-Šām (c. 1800-1600 BCE)

The present thesis investigates the material scale of six political economiesdistributed across the dry-farming plains and piedmonts of the Middle Bronze AgeJazīrah and the Bilād al-Šām. This is done using a comparative and interdisciplinaryapproach combining the large-scale analysis of administrative cuneiform texts withthe compilation of relevant archaeological survey datasets. Drawing on theori

Transmission spectroscopy of CF4 molecules in intense x-ray fields

The nonlinear interaction of x rays with matter is at the heart of understanding and controlling ultrafast molecular dynamics from an atom-specific viewpoint, providing new scientific and analytical opportunities to explore the structure and dynamics of small quantum systems. At increasingly high x-ray intensity, the sensitivity of ultrashort x-ray pulses to specific electronic states and emerging

Environment of European Last Mammoths : Reconstructing the Landcover of the Eastern Baltic Area at the Pleistocene/Holocene Transition

The Eastern Baltic area stands out as a unique location due to the finds of Europe’s youngest dated mammoth remains (12.6–11.2 ka cal BP). Our study explores the drastic climate and landcover changes during the extinction of these gigantic herbivores at the Pleistocene/Holocene boundary. We used macrofossil analysis to determine the major contemporary terrestrial plant genera present in the area a

High migratory potential of fall armyworm in West Africa despite stable temperatures and widely available year-round habitats

The fall armyworm (FAW), an important migratory pest native to the Americas, was first detected in a nonnative region (West Africa) in 2016. In the following years, it quickly spread to multiple regions worldwide. FAW exhibits long-distance seasonal migration in both the Americas and Asia, primarily to take advantage of suitable seasonal habitats as they appear along the migratory pathways. Tropic

A murine pressure ulcer model for evaluating persistence and treatment of Staphylococcus aureus infection

Chronic wounds, particularly pressure ulcers, pose significant healthcare challenges, especially in the elderly population. This study presents an experimental murine model of chronically infected pressure ulcers using a single cycle of magnet-induced ischemic injury combined with infection by bioluminescent Staphylococcus aureus. The model addresses previous limitations in studying pressure ulcer

Constraints and Costs : Essays in Corporate Finance

This thesis investigates how firms respond to internal and external financial pressures through four self-contained empirical studies in corporate finance. The first study explores how asset tangibility influences investment behaviour, finding that firms with more physical assets exhibit stronger sensitivity of investment to cash flow, indicating a deeper role for tangibility beyond traditional fi

Electromechanical coupling in polaronic ceria

Oxygen-defective metal oxides like cerium oxides exhibit giant electrostriction and field-induced piezoelectricity due to a dynamic electrosteric interplay between oxygen defects, V O ⋅ ⋅ , and the fluorite lattice. While such mechanisms are generally attributed to oxygen vacancies, recent results also highlight that trapped cationic defects, Ce Ce ′ , i.e. small polarons, can contribute to the el

Valuing drought impact mitigation on ecosystem services in a Mediterranean country

Drought is a complex natural hazard increasing in frequency, duration, and severity worldwide. Although droughts cause both market and non-market impacts, the latter suffers from a dearth of economic studies quantifying their magnitude. In this paper, we investigated how droughts affect selected ecosystem services expected to result in welfare losses in Spain. This study is aimed at quantifying an

Influence of land cover on noise simulation output – A case study in Malmö, Sweden

Determining the land cover (LC) data requirements used as input to noise simulations is essential for planning sustainable urban densifications. This study examines how different LC datasets influence simulated environmental noise levels of road traffic using Nord2000 in an urban area of 1 km2 in southern Sweden. Four LC datasets were used. The first dataset was based on satellite data (spatial re

A Novel Decentralized Leader–follower Control Scheme for Centroid and Formation Tracking

This paper deals with the centroid and formation control problem of multi–agent robotic systems. The proposed solution is based on a leader–follower scheme, where only a subset of agents, i.e., the leaders, knows the desired trajectories for the centroid and the formation of the system, while the other agents, i.e., the followers, are required to estimate them through a dynamic consensus scheme. T

Economic evaluations of strategies targeting pre-diagnosis dementia populations : Protocol for a systematic review

Introduction: Dementia remains incurable, and treatment trials are typically conducted after the symptoms manifest, potentially too late in the disease process to alter its course. Early identification and intervention during the pre-diagnosis phase offer the potential to introduce more cost-effective strategies and enhance quality of life. This review aims to scrutinise emerging evidence and pres

Naturanpassade skyddsvallar mot stormfloder : Planering, anläggning, och förvaltning

Denna rapport är framtagen genom det Vinnova-finansierade projektet ”Naturbaserade skyddsvallar mot översvämning – planering, anläggning och förvaltning”. Projektet har varit ett samarbete mellan Vellinge kommun, Lunds universitet, Ecogain AB och Statens geotekniska institut (SGI). Föreliggande rapport är en sammanställning av de kunskaper och erfarenheter som har erhållits under detta projekt.

Evaluation of the adsorptive behaviour of kraft black liquor on nanofiltration model membrane surfaces via quartz crystal microbalance with dissipation monitoring (QCM-D)

Membrane filtration of kraft black liquor (KBL), a side-stream of the pulp and paper industry, is challenged by membrane fouling caused by its multicomponent complexity. The specific contributions of the components found in KBL to the fouling and the characteristics of the fouling layer that they create has not been investigated. Herein, the adsorptive and desorptive behaviours of KBL ultrafiltrat

Hydration enthalpies of amorphous sucrose, trehalose and maltodextrins and their relationship with heat capacities

The mechanisms of glass transitions and the behavior of small solute molecules in a glassy matrix are some of the most important topics of modern thermodynamics. Water plays an important role in the physical and chemical stability of lyophilized biologics formulations, in which glassy carbohydrates act as cryoprotectants and stabilizers. In this study, sorption calorimetry was used for simultaneou

An atomic force microscopy approach for assessment of particle density applied to single spray-dried carbohydrate particles

To evaluate an atomic force microscopy (AFM) approach for effective density analysis of single spray dried carbohydrate particles in order to investigate the internal structure of the particles. In addition, the AFM method was compared to an established technique, that is gas pycnometry. Resonant frequency AFM analysis was employed for determination of the mass of individual particles of spray-dri