Search results

Filter

Filetype

Your search for "*" yielded 529328 hits

UPF2 Is a Critical Regulator of Liver Development, Function and Regeneration

Background: Nonsense-mediated mRNA decay (NMD) is a post-transcriptional RNA surveillance process that facilitates the recognition and destruction of mRNAs bearing premature terminations codons (PTCs). Such PTC-containing (PTC+) mRNAs may arise from different processes, including erroneous processing and expression of pseudogenes, but also from more regulated events such as alternative splicing co

Fibroblasts as architects of cancer pathogenesis

Studies of epithelial cancers (i.e., carcinomas) traditionally focused on transformation of the epithelium (i.e., the cancer cells) and how aberrant signaling within the cancer cells modulates the surrounding tissue of origin. In more recent decades, the normal cells, blood vessels, molecules, and extracellular components that surround the tumor cells, collectively known as the "tumor microenviron

Inclusive J/psi production in pp collisions at root s=2.76 TeV

The ALICE Collaboration has measured inclusive J/psi production in pp collisions at a center-of-mass energy root s = 2.76 TeV at the LHC. The results presented in this Letter refer to the rapidity ranges vertical bar y vertical bar < 0.9 and 2.5 < y

Recension av Anders Jarlerts Drottning Victoria

Recension av en existentiell biografi om drottning Victoria, som fokuserar mycket på hennes religiösa liv och hennes pliktmedvetande, samt illustrerar hur hon kan betraktas som tillhörande "förlorarnas historia".

Client perceptions of the Tree Theme Method: a structured intervention based on storytelling and creative activities.

The Tree Theme Method (TTM) is an intervention based on sessions involving creative activities and life storytelling/story-making, in which the client paints trees representing various periods of his/her life. The aim of this study was to investigate clients' experiences of participating in a TTM intervention and their perceptions of the therapeutic relationship. Thematic interviews were undertake

A procedure for the characterization of electron transmission through Frisch grids

In Frisch grid ionization chambers special attention must be paid to the operating voltages in order to avoid unwanted collection of electrons on the Frisch grid. Collection of electrons on the grid will lead to a decreased signal to noise ratio and consequently a deteriorated energy resolution. Furthermore, systematic errors in the determination of the angular distribution will be introduced. The

The impact of personality factors on delay in seeking treatment of acute myocardial infarction

Background: Early hospital arrival and rapid intervention for acute myocardial infarction is essential for a successful outcome. Several studies have been unable to identify explanatory factors that slowed decision time. The present study examines whether personality, psychosocial factors, and coping strategies might explain differences in time delay from onset of symptoms of acute myocardial infa

Performance of tree phenology models along a bioclimatic gradient in Sweden

Tree phenology has been recognized as an important indicator of climate change, and a wide range of budburst models have been developed. The models differ in temperature sensitivity, and the choice of model can therefore influence the result of climate impact assessments. In this study we compared the ability of 15 models to simulate budburst of the main forest tree species in Sweden. Records on t

Small and large PROS1 deletions but no other types of rearrangements detected in patents with protein S deficiency

Protein S deficiency is a dominantly inherited disorder that results from mutations in the PROS] gene. Previous sequencing of the gene failed to detect mutations in eight out of 18 investigated Swedish families, whereas segregation analyses detected large deletions in three out of the eight families. The present study investigates more thoroughly for the presence of deletions but also for other ty

Precursor-Less Coating of Nanoparticles in the Gas Phase

This article introduces a continuous, gas-phase method for depositing thin metallic coatings onto (nano)particles using a type of physical vapor deposition (PVD) at ambient pressure and temperature. An aerosol of core particles is mixed with a metal vapor cloud formed by spark ablation by passing the aerosol through the spark zone using a hollow electrode configuration. The mixing process rapidly

Philopatric predisposition to predation-induced ecological traps: habitat-dependent mortality of breeding eiders

Because population size is sensitive to changes in adult survival, adult survival may be buffered against environmental variability. Philopatry may be adaptive in changing environments, but it could also constrain breeding habitat selection under changing conditions such as shifting predation regimes. Habitat preference and quality could become decoupled in long-lived philopatric species that evol

Transcriptional analysis of the pheromone gland of the turnip moth, Agrotis segetum (Noctuidae), reveals candidate genes involved in pheromone production.

Moths generally rely on pheromone communication for mate finding. The pheromone components of most moths are produced by a common pathway of fatty-acid biosynthesis coupled with species-specific modifications of the final products. Some genes involved in moth pheromone production have previously been described, whereas others remain to be characterized and thus the molecular mechanisms accounting