Sex Differences in Longitudinal Tau-PET in Preclinical Alzheimer Disease : A Meta-Analysis
Importance: Alzheimer disease (AD) predominates in females at almost twice the rate relative to males. Mounting evidence in adults without AD indicates that females exhibit higher tau deposition than age-matched males, particularly in the setting of elevated β-amyloid (Aβ), but the evidence for sex differences in tau accumulation rates is inconclusive. Objective: To examine whether female sex is a
