Recent advances in therapeutics are now providing a wide range of options for adults and children living with hemophilia. Although therapeutic choices are also increasing for the youngest individuals with severe disease, challenges remain about early management decisions, as supporting data are currently limited. Parents and healthcare professionals are tasked with helping children achieve an incl

3D integration of III-V semiconductors with Si CMOS is highly attractive since it allows combining new functions such as photonic and analog devices with digital signal processing circuitry. Thus far, most 3D integration approaches have used epitaxial growth on Si, layer transfer by wafer bonding, or die-to-die packaging. Here we present low-temperature integration of InAs on W using Si3N4 templat

Background The health of people with functional variation in Sweden is worse than people without functional variation. A health-promoting resource in adults’ lives is meaningful employment, and for people with functional variation it means some form of daily activity. The project "Grow with horsepower" is a person-centered and nature-oriented daily activity for people with function variation, who

In winter, a challenge to the immune system could pose a major energetic trade-off for small endotherms, whereby increasing body temperature (Tb; i.e. eliciting fever) may be beneficial to fight off invading pathogens yet incur a cost for vital energy-saving mechanisms. Having previously shown that the availability and acquisition of energy, through manipulation of food predictability, influences

This review summarizes and exemplifies the current understanding of osteoarthritis in vitro models and describes their relevance for new insights in the future of osteoarthritis research. Our friend and highly appreciated colleague, Prof. Alan Grodzinsky has contributed greatly to the understanding of joint tissue biology and cartilage biomechanics. He frequently utilizes in vitro models and carti

This chapter explores moral and ethical discussions that emerged in Sweden when the number of artificial grass pitches rose substantially. Based on research in the Swedish top-tier football league, named Allsvenskan, I shall present conflicting discourses that appear whenever grass is considered. The grass discussions often take a wider, political turn and reflect attitudes towards developments in

This chapter presents information on hydrogen as an energy carrier, its properties, how to produce and store it, how to transport it, as well as its role in future energy systems. Opportunities and concerns about hydrogen are discussed. The basic principles and analysis of the key transport phenomena, bottlenecks, and applications of fuel cells are discussed. Most attention is paid to so-called PE

Background: Women are less likely to receive oral anticoagulation or ablation for treatment of atrial fibrillation (AF). Identification of sex differences in arrhythmia characteristics and symptoms may lead to a better understanding of potential reasons for these differences. Objectives: To determine sex differences in AF with respect to heart rate, duration, burden, and symptoms in patients under

What is a football stadium? A structure that is most of the time empty in everyday life, but bursts with energy on matchdays. Its construction and maintenance cost a fortune, it occupies a lot of precious urban space and most often seems to facilitate undesired behaviour, such as letting off flares and smoke bombs, throwing chairs or water bottles, abusing and disparaging adversaries in any imagin

This chapter focuses on the dominantly gendered house-help in India: the cooks, cleaners, and maids during the pandemic-triggered lockdowns in Delhi and its metropolitan areas. Even if we are scared to enter people's homes, we have to come out to work to sustain our lives. The case studies of these three women point to the precarity and 'unrepresentability' which turn the previously invisible figu

Several lines of research within developmental psychology, experimental semiotics and language origins studies have recently converged in their interest in pantomime as a system of bodily communication distinct from both language (spoken or signed) and nonlinguistic gesticulation. These approaches underscore the effectiveness of pantomime, which despite lack of semiotic conventions is capable of c

A displaced femoral neck fracture in a person around retirement age, with some comorbidities, poses challenges in determining the optimal surgical treatment. The long-term result will be affected by the patient's overall health, their life style factors, and the patient's compliance with restrictions. Ideally, the surgeon has to foresee the vitality of the patient during his/her remaining life spa

Introduction. Recently, more attention is being paid to the drug-induced liver injury (DILI) as a consequence of the tuberculos is treatment and the need for new medicine is emphasized. The use of isoniazid and rifampicin has a potentiating effect, which increases the risk of substancial liver damage. In turn, systemic accumulation of toxic metabolites leads to negative changes in various organs,

This chapter presents a clinical scenario of a 59-year-old healthy woman who had injures in her dominant wrist after a fall at home. Her wrist radiographs show a displaced extra-articular distal radius fracture with a dorsal angulation of 15 ° (from 0 °) and an ulnar variance of 3 mm. The treating surgeon has a discussion with the patient about surgical and nonsurgical treatment options and the ex

Quinoa (Chenopodium quinoa Willd.) has gained recent popularity mainly due to its attractive nutritional profile and its ability to grow under extreme conditions such as salinity, acidity, drought, flooding, and frost as well as the functionality of its component. Starch is the main component of quinoa grain which constitutes up to 60% of the dry grain and plays a crucial role in the functional pr

Glioblastoma multiforme (GBM) is the most common and aggressive brain tumor in adults and is highly resistant to chemo- and radiotherapies. GBM has been associated with alterations in lipid contents, but lipid metabolism reprogramming in tumor cells is not fully elucidated. One of the key hurdles is to localize the lipid species that are correlated with tumor growth and invasion. A better understa

As climate change and rapid urbanization stress our aging water infrastructure, cities are under increasing pressure to develop more flexible, resilient, and modular water management systems. In response, onsite water reuse practices have been adopted by several cities globally. In addition to technological innovation, these novel water treatment systems also require new stakeholder collaborations