Large-scale linear systems arise in finite-difference and finite-element discretizations of elliptic problems. With increasing computer performance, ever larger systems are solved using direct methods. How large can such systems be without roundoff compromising accuracy? Here we model roundoff dynamics in standard LU and LDLT decompositions with respect to problem size N. For the one-dimensional (

Dipterological surveys were conducted in different sites in western and central parts of northern Iran (Guilan, Mazandaran, Kordestan, East and West Azerbaijan and Ardabil provinces) during 2010–2011 using Malaise traps, and during 2012–2014 employing sweep nets. A total of 110 species were collected, including 42 Dolichopodinae. Eleven dolichopodine species proved new to science, eight of which a

In 1935, a law on prescription-based sterilisation of ‘the idiot, the imbecile, and the mentally ill’ was passed by a majority in the Finnish parliament. Complementary of earlier eugenic legislation, it was considered beneficial for public health and economy, following the examples of ‘advanced’ countries such as Sweden and Germany. The cultural journal Tulenkantajat (The Fire Bearers, 1932-1939)

Hydrological climate change impact assessment is generally performed by following a sequence of steps from global and regional climate modelling, through data tailoring (bias-adjustment and downscaling) and hydrological modelling, to analysis and impact assessment. This “climate-hydrology-assessment chain” has been developed with a primary focus on applicability to a medium-sized rural basin, whic

Aims Optimal antithrombotic therapy after percutaneous coronary intervention (PCI) in patients with myocardial infarction (MI) and atrial fibrillation is uncertain. In this study, we compared antithrombotic regimes with regard to a composite cardiovascular outcome of all-cause mortality, MI or ischaemic stroke, and major bleeds. Methods and results Patients between October 2005 and December 2012 w

Aim: Having a known midwife at birth is valued by women across the world, however it is unusual for women with fear of childbirth to have access to this model of care. The aim of this study was to describe the prevalence and factors related to having access to a known midwife for women referred to counseling due to childbirth fear. We also wanted to explore if women's levels of childbirth fear cha

At the southern margin of permafrost in North America, climate change causes widespread permafrost thaw. In boreal lowlands, thawing forested permafrost peat plateaus (‘forest’) lead to expansion of permafrost‐free wetlands (‘wetland’). Expanding wetland area with saturated and warmer organic soils is expected to increase landscape methane (CH4) emissions. Here, we quantify the thaw‐induced increa

Over the last several decades the hydrologically sensitive Boreal Plains ecoregion of Western Canada has experienced significant warming and drying. To better predict implications of land cover changes on evapotranspiration (ET) and future water resources in this region, high resolution light detection and ranging and energy balance data are used here to spatially parameterize the Penman-Monteith

Spaceborne laser altimetry waveform estimates of canopy Gap Fraction (GF) vary with respect to discrete return airborne equivalents due to their greater sensitivity to reflectance differences between canopy and ground surfaces resulting from differences in footprint size, energy thresholding, noise characteristics and sampling geometry. Applying scaling factors to either the ground or canopy porti

The Geoscience Laser Altimeter System (GLAS) has the potential to accurately map global vegetation heights and fractional cover metrics using active laser pulse emission/reception. However, large uncertainties in the derivation of data products exist, since multiple physically plausible interpretations of the data are possible. In this study a method is described and evaluated to derive vegetation

Pseudouridylation (Ψ) is the most abundant and widespread type of RNA epigenetic modification in living organisms; however, the biological role of Ψ remains poorly understood. Here, we show that a Ψ-driven posttranscriptional program steers translation control to impact stem cell commitment during early embryogenesis. Mechanistically, the Ψ “writer” PUS7 modifies and activates a novel network of t

In the sporadic permafrost zone of northwestern Canada, boreal forest carbon dioxide (CO2) fluxes will be altered directly by climate change through changing meteorological forcing and indirectly through changes in landscape functioning associated with thaw‐induced collapse‐scar bog (‘wetland’) expansion. However, their combined effect on landscape‐scale net ecosystem CO2 exchange (NEELAND), resul

In Arctic fjords and high‐latitude seas, strong surface cooling dominates during a large part of the year, generating water‐side convection (w* w) and enhanced turbulence in the water. These regions are key areas for the global carbon cycle; thus, a correct description of their air‐sea gas exchange is crucial. CO2 data were measured via the eddy covariance technique in marine Arctic conditions and

Young children with visual impairments tend to engage less with their surroundings, limiting the benefits from activities at school. We investigated novel ways of using sound from a bracelet, such as speech or familiar noises, to tell children about nearby people, places and activities, to encourage them to engage more during play and help them move independently. We present a series of studies, t