Osteoarthritis is a harmful joint disease but prediction of disease progression is problematic. Currently, there is only one modeling framework which can be applied to predict the progression of knee osteoarthritis but it only considers degenerative changes in the collagen fibril network. Here, we have developed the framework further by considering all of the major tissue changes (proteoglycan con

In order to investigate the molecular mechanisms by which the oncogenic mutant KIT/D816V causes transformation of cells, we investigated proteins that selectively bind KIT/D816V, but not wild-type KIT, as potential mediators of transformation. By mass spectrometry several proteins were identified, among them a previously uncharacterized protein denoted XKR5 (XK-related protein 5), which is related

This study aims to shed new light on the petroglyphs found at the site of Aspeberget 12 at the World Heritage site of Tanum, Sweden, from a semiotic perspective. We demonstrate the semiotics of power inherent in the arrangement of the petroglyphs. We start by describing the site in an archaeological way, in order to give an overview of the empirical material used in this case study. Against the ba

Purpose: This study examines how voice quality and multitalker babble noise affect immediate passage comprehension and the efficiency of information encoding into long-term memory in children with normal hearing. Method: Eighteen children (mean age = 9 years) with normal hearing participated. Immediate passage comprehension performance and delayed performance (after 5 to 8 days) were assessed for

The structural study of glycans and glycoconjugates is essential to assign their roles in homeostasis, health, and disease. Once dominated by nuclear magnetic resonance spectroscopy, mass spectrometric methods have become the preferred toolbox for the determination of glycan structures at high sensitivity. The patterns of such structures in different cellular states now allow us to interpret the s

There is an increasing demand for trustworthy engineering geological conceptual models in urban areas due to an increasing trend in the underground infrastructure construction. Good-quality site investigations can reduce the risk of encountering unexpected geological conditions during construction. Geoelectrical measurements can be used as a tool for providing an overview of the site conditions an

Purpose: A traffic safety analysis that is based on registered crashes often suffers from underreporting, which may result in biased conclusions and lead to misguided crash-prevention strategies. Self-reporting traffic crashes is a complementary method to obtain crash information that is often not available in official databases. By surveying studies from around the world, this paper aims to map t

I argue that Paul Ricœur displaces and decentres established theodicies; the issue of evil is perceived as a practical rather than a speculative matter. It is the view of evil as a productive aporia, which suggests that evil provokes action and obliges human beings to take a stand ethically and politically. Hence, the topic of evil is not necessarily about putting together a jigsaw puzzle. The cen

This chapter starts with the question of how damages for violation through crime are determined by law. Compensation for criminal injuries is the predominant type of non-pecuniary damages in Swedish tort law. Yet, a fundamental uncertainty exists regarding computation of damages and the legal meaning of ‘violation’. The general consensus in the legal profession is that norms for computation of damThis chapter starts with the question of how damages for violation through crime are determined by law. Compensation for criminal injuries is the predominant type of nonpecuniary damages in Swedish tort law. Yet, a fundamental uncertainty exists regarding computation of damages and the legal meaning of ‘violation’. The general consensus in the legal profession is that norms for computation of dama

Syftet med studien är att undersöka det förbättrade upptaget av det radioaktiva spåret Technetium-99m-DTPA (99mTc-DTPA) i råtta Muskelvävnad i Fischer 344 råttor efter applicerade elektriska pulser med olika fältstyrka och pulslängd,Metoder: 99mTc-DTPA (totalt 150 MBq) administrerades intramuskulärt (i.m.) vid axeln som en bolus i flera fraktioner av 50 l vardera i intervaller på 1 minut. Bilder

Skin disease and its therapy affect health-related quality of life (HRQoL). The aim of this study was to measure the burden caused by dermatological therapy in 3,846 patients from 13 European countries. Adult outpatients completed questionnaires, including the Dermatology Life Quality Index (DLQI), which has a therapy impact question. Therapy issues were reported by a majority of patients with ato

Three-dimensional (3D) solar maps based on Radiance simulations are presented for a future city district in southern Norway. The surface mapping method provides the commercial developer with a practical tool to evaluate the potential for building integrated photovoltaics (BIPV). The solar maps identify the optimum roof and facade areas available for solar energy utilization. The importance of BIPV

Self-service business intelligence (SSBI) is an emerging trend in organisations allowing users to become more autonomous in data exploration. Organisations are keen to provide such services for their employees due to its potential benefits. However, there is little empirical knowledge about the process of building a SSBI service and the role of users in this process. From an exploratory single cas

We present an analytic representation of FK/Fπ as calculated in three-flavor two-loop chiral perturbation theory, which involves expressing three mass scale sunsets in terms of Kampé de Fériet series. We demonstrate how approximations may be made to obtain relatively compact analytic representations. An illustrative set of fits using lattice data is also presented, which shows good agreement with