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Performance of lignin derived aromatic oxygenates in a heavy-duty diesel engine

The possibility to reduce dependence on fossil fuel resources has led to an increasing interest in the use of bio-fuels. This study builds on earlier work on (aromatic) cyclic oxygenates [1,2], but a far wider window of engine operation has been investigated in this paper. Two parametric variations of engine operation were performed and discussed: (1) non-EGR operation by means of varying the load

Frequency, Genotype, and Clinical Spectrum of Best Vitelliform Macular Dystrophy: Data From a National Center in Denmark

PURPOSE: To estimate the prevalence, genotype, and clinical spectrum of Best vitelliform macular dystrophy (Best disease). DESIGN: Retrospective epidemiologic and clinical and molecular genetic observational study. METHODS: SETTING: National referral center. PARTICIPANTS: Forty-five individuals diagnosed with Best disease. OBSERVATION PROCEDURES: Retrospective review of patients diagnosed accordin

Genetic associations to germinal centre formation in primary Sjogren's syndrome

Background Primary Sjogren's syndrome (pSS) is an autoimmune rheumatic disease mainly characterised by focal mononuclear cell infiltration in the salivary and lacrimal glands, and by the symptoms xerostomia and keratoconjunctivitis sicca. Germinal centre-like structures (GC) are found in the minor salivary glands of approximately 25% of patients. In this study, we aimed to assess genetic variation

Contingent Management of Supply Chain Disruption: Effects of Dual or Triple Sourcing

This paper studies a single product setting in which a firm can source from multiple suppliers. One supplier has unreliable capacity while other suppliers are reliable but have lower product quality. The addressed context (where a case study has been made) is disruptions due to sanctions which cause failure in the supply from the unreliable source. The important question which emerges here is how

How do episodic and semantic memory contribute to episodic foresight in young children?

Humans are able to transcend the present and mentally travel to another time, place, or perspective. Mentally projecting ourselves backwards (i.e., episodic memory) or forwards (i.e., episodic foresight) in time are crucial characteristics of the human memory system. Indeed, over the past few years, episodic memory has been argued to be involved both in our capacity to retrieve our personal past e

Prevalence, incidence and progression of hand osteoarthritis in the general population: the Framingham Osteoarthritis Study

Objectives To describe the prevalence and longitudinal course of radiographic, erosive and symptomatic hand osteoarthritis (HOA) in the general population. Methods Framingham osteoarthritis (OA) study participants obtained bilateral hand radiographs at baseline and 9-year follow-up. The authors defined radiographic HOA at joint level as Kellgren-Lawrence grade (KLG)>= 2, erosive HOA as KLG >= 2 pl

Climate change and energy policy in Chile: Up in smoke?

This paper provides an ex-post assessment of the climate and energy policy developments in Chile emerging from a neoliberal economic model, during the period 1971-2007. First, correlation and regression analyses were performed to analyse historical CO2 emissions as a product of demographic, economic and energy-wide drivers. Then I estimate indicators related to CO2 emissions, energy use and econom

Contributions of climate, leaf area index and leaf physiology to variation in gross primary production of six coniferous forests across Europe: a model-based analysis

Gross primary production (GPP) is the primary source of all carbon fluxes in the ecosystem. Understanding, variation in this flux is vital to understanding variation in the carbon sink of forest ecosystems, and this would serve as input to forest production models. Using GPP derived from eddy-covariance (EC) Measurements, it is now possible to determine the most important factor to scale GPP acros

Glycosylation of the two O-glycosylated domains of human MUC2 mucin in patients transposed with artificial urinary bladders constructed from proximal colonic tissue

Transposition of intestinal segments is frequently used for bladder reconstruction. Following transposition, bowel segments continue to produce mucus and a correlation between excessive mucus production and complications such as urinary tract infection or catheter blockage has been observed for a long time. However, no information is currently available on the change of mucin expression and glycos

Challenges and Opportunities in Managing the Dizzy Older Adult

Balance disorders are common in elderly people, not only resulting in distressing sensations but also leading to reduced activity levels and quality of life. It has been estimated that 30% of elderly patients experience a balance disorder. Managing these disorders is a substantial challenge for patients and their caregivers and physicians. Moreover, abnormalities in balance are associated with fal

Improving the Quality of Pharmacotherapy in Elderly Primary Care Patients Through Medication Reviews: A Randomised Controlled Study

Background Polypharmacy in the Swedish elderly population is currently a prioritised area of research with a focus on reducing the use of potentially inappropriate medications (PIMs). Multi-professional interventions have previously been tested for their ability to improve drug therapy in frail elderly patients. Objective This study aimed to assess a structured model for pharmacist-led medication

Measure for measure. Outcome assessment of arthritis treatment in clinical practice

Objective: To investigate (i) the performance and agreement between various activity indices and response criteria in TNF-blockade of RA; (ii) the predictive ability of different response criteria and disease activity states regarding continuation of anti-TNF treatment of RA; (iii) Euro-QoL-5-dimensions utility development during TNF blockade of RA, PsA and SpA. Also, (iv) to develop a simple, uti

Determining a temperature differential across a quantum dot

We present a method for determining a temperature differential across a quantum dot. If the device has a transmission function with sufficiently spaced resonant energies, then one can distinguish electrons which have tunneled from the hot lead, and those which have tunneled from the cold lead. By measuring the thermocurrent as the electrochemical potential is swept through a resonant energy level,

The Artelon CMC spacer compared with tendon interposition arthroplasty

Background and purpose The Artelon CMC spacer is designed for surgical treatment of osteoarthritis (OA) in the carpometacarpal joint of the thumb (CMC-I). Good results using this degradable device were previously presented in a pilot study. We now present results from a larger randomized, controlled, multicenter study. Patients and methods 109 patients (94 females) with a mean age of 60 (42-83) ye