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[FeFe]-hydrogenases are highly efficient H(2)-evolving metalloenzymes that include cyanides and carbonyls in the active site. The latter is an Fe(6)S(6) cluster (the so-called H-cluster) that can be subdivided into a binuclear portion carrying the CO and CN(-) groups and a tetranuclear subcluster. The fundamental role of cyanide ligands in increasing the basicity of the H-cluster has been highligh

Most of the prostate cancers (PCa) in advanced stage will progress to castration-resistant prostate cancer (CRPC). Within CRPC group, 50-70% of the patients will develop bone metastasis in axial and other regions of the skeleton. Once PCa cells spread to the bone, currently, no treatment regimens are available to eradicate the metastasis, and cancer- related death becomes inevitable. In 2012, it i

The indigenista novel is a realistic novel with a strongly ideological character that was developed primarily in the Andean countries (Peru, Bolivia, Ecuador) during the first half of the 20th century with the purpose of making the reader aware of the living conditions of the indigenous Native American population. The overall aim of this study was to investigate the female characters in five of th

The stability of the Nystrom method for the Muskhelishvili equation on piecewise smooth simple contours Gamma is studied. It is shown that in the space L-2 the method is stable if and only if certain operators A tau(j) from an algebra of Toeplitz operators are invertible. The operators A tau(j) depend on the parameters of the equation considered, on the opening angles theta(j) of the corner points

A central hypothesis of ecological immunology is that immune defences are traded off against competing physiological and behavioural processes. During energetically demanding periods, birds are predicted to switch from expensive inflammatory responses to less costly immune responses. Acute phase responses (APRs) are a particularly costly form of immune defence, and, hence, seasonal modulations in

En av Sveriges ledande botanister har gått ur tiden. Sven Snogerup (1929-2013), hedersmedlem i Svenska Botaniska Föreningen sedan 1999, porträtteras här av Ingvar Kärnefelt.

Background: Most studies assessing health effects of neighborhood characteristics either use self-reports or objective assessments of the environment, the latter often based on Geographical Information Systems (GIS). While objective measures require detailed landscape data, self-assessments may yield confounded results. In this study we demonstrate how self-assessments of green neighborhood enviro

Although climate is known to be one of the key factors determining animal species distributions amongst others, projections of global change impacts on their distributions often rely on bioclimatic envelope models. Vegetation structure and landscape configuration are also key determinants of distributions, but they are rarely considered in such assessments. We explore the consequences of using sim

Diabetes is increasing worldwide and hence the risk developing complications where retinopathy is the theme of this study. The aim of the study was to evaluate the presence of (vascular) retinopathy in subjects with the pre-diabetes stage, impaired fasting glucose (IFG), and the development of retinopathy in these subjects during five years. In the second part of the study diabetes patients with d

There have been extensive discussions in academic circles of why some countries develop into welfare states while others do not. Two main factors mentioned in these discussions are economic growth and the need for political stability. In these discussions, the example of Sweden, where the welfare state allegedly emerged from a ‘culture of consensus’, has often been treated as an historic exception

Background: Enhancement of enzymatic digestibility by some supplementations could reduce enzyme loading and cost, which is still too high to realize economical production of lignocellulosic biofuels. A recent study indicates that yeast hydrolysates (YH) have improved the efficiency of cellulases on digestibility of furfural residues (FR). In the current work, the components of YH were separated by

Pneumothorax occurs more frequently in the neonatal period than at any other time of life and is associated with increased mortality and morbidity. It may be treated with either needle aspiration or insertion of a chest tube. The former consists of aspiration of air with a syringe through a needle or an angiocatheter, usually through the second or third intercostal space in the midclavicular line.

High-resolution core-level spectroscopy and density-functional theory calculations have been used to investigate CO adsorption on the p(4 x 4) structure of oxidized Ag(111). CO adsorption with subsequent carbonate formation was observed at 100 K. The experimental results are consistent with calculations that reveal low activation barriers to form CO2 and CO32- from adsorbed CO. On the basis of a g

Vid fångst av nattfjärilar använder man ofta lockbeten. De består av en trasa eller liknande som dränks in med någon lockande vätska och hängs upp i t.ex. ett träd. Under natten kan betet inspekteras många gånger och djur samlas in. Recepten för den lockande vätska varierar kraftigt mellan olika samlare men innehåller alltid jästa produkter av något slag. En stor skiljelinje går mellan beten som b

We previously demonstrated that hyperglycemia could suppress apolipoprotein M (apoM) synthesis both in vivo and in vitro; however, the mechanism of hyperglycemia-induced downregulation of apoM expression is unknown yet.

We explore the signatures of Majorana fermions in a nanowire based topological superconductor-quantum dot-topological superconductor hybrid device by charge transport measurements. At zero magnetic field, well-defined Coulomb diamonds and the Kondo effect are observed. Under the application of a finite, sufficiently strong magnetic field, a zero-bias conductance peak structure is observed. It is f

Aims: To analyse, at a one year follow up, cost offset and outcomes of changing the physical activity (PA) behaviour due to a primary care intervention. Methodology: Participants were 528 inactive individuals with life-style related health problems, 18-84 years, and randomised into a high-dose intervention group (n=270) or a low-dose intervention group (n=258). The four month lasting intervention