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Usefulness of the Sum Absolute QRST Integral to Predict Outcomes in Patients Receiving Cardiac Resynchronization Therapy

Cardiac resynchronization therapy (CRT) reduces mortality and morbidity in selected patients with heart failure (HF), but up to 1/3 of patients are nonresponders. Sum absolute QRST integral (SAI QRST) recently showed association with mechanical response on CRT. However, it is unknown whether SAI QRST is associated with all-cause mortality and HF hospitalizations in patients undergoing CRT. The stu

Copeptin, a Marker of Vasopressin, Predicts Vascular Dementia but not Alzheimer's Disease

Background: Copeptin is a reliable surrogate marker for the neurohypophyseal hormone vasopressin. Elevated plasma level of copeptin has been associated with cardiovascular and metabolic disease risk. Objective: To investigate the association between copeptin and risk of dementia. Methods: In all, 18,240 individuals from Malmö, Sweden, were examined between 2002 and 2006 (mean age 69.3 years, 69.8

N-nitrosamines in the southern Swedish rubber industries - exposure, health effects, and immunologic markers

OBJECTIVES: The aim of this study was twofold: (i) to evaluate the air levels of N-nitrosamines in the Swedish rubber industry and (ii) to estimate the risk of symptoms and changed levels of immunologic markers in relation to these levels.METHODS: Using adsorption tubes, we collected samples of N-nitrosamines in the breathing zone of 96 rubber workers and analyzed them with liquid chromatography t

No quick fixes : four interacting constraints to advancing agroecology in Uganda

A century after its inception, agroecology has entered mainstream development debates as a more sustainable alternative to conventional agricultural modernization of relevance not least for improving smallholder agriculture in sub-Saharan Africa. Agroecology is a broad concept considered to have transformative potential, yet as a research field it has often been technology-centred and focused at t

Health transition after lung transplantation - a grounded theory study

Aims and objectives: To investigate lung recipients' process of transition from prior the transplantation to one year afterwards, as well as what their main concerns are and how they deal with these concerns. Background: During the last three decades, lung transplantation has been established as an effective treatment for patients with end-stage pulmonary disease. Towards the end of the 20th centu

The Mullnäset rapakivi granite, its chemical and mineralogical composition including a comparison with the Sörvik granite, west central Sweden.

This contribution presents complimentary mineralogical and whole-rock chemical data for the Mullnäset rapakivi massif. Three rock types occur: gabbro, syenite with associated granite and “normal” rapakivi granite, here denoted rapakivi-textured granite. In the syenite-associated granite, extremely Mg-poor clinopyroxene and fayalite are the most important mafic minerals, whereas ferrohornblende and

'The city disinterred' : the Shelley circle and the revolution at Naples

This essay examines Byron's and Shelley's reactions to, and involvement with, the Neapolitan Revolution of 1820–21, using them to focus a debate about conflicting constructions of history in their writing, and to question subsequently conventional accounts of their creative relationship. It concentrates on Shelley's Ode to Naples, which it identifies as in important rhetorical blow in Shelley's pu

Barns behov av information, råd och stöd när en förälder får vuxenpsykiatrisk vård - Hur efterföljs lagen i den kliniska vardagen?

Omfattande forskning pekar på att en förälders psykiska ohälsa kan utgöra enriskfaktor för barnens psykiska utveckling och hälsa, inte minst när den psykiska ohälsan gör det svårt för föräldern att fullt ut fungera som förälder. Sedan år2010 finns ett tillägg i hälso- och sjukvårdslagen om att vården ska beakta barnensbehov av information, råd och stöd och det finns idag ett flertal insatser att v

The evolution of substrate specificity-associated residues and Ca2+-binding motifs in EF-hand-containing type II NAD(P)H dehydrogenases

Most eukaryotic organisms, except some animal clades, have mitochondrial alternative electron transport enzymes that allow respiration to bypass the energy coupling in oxidative phosphorylation. The energy bypass enzymes in plants include the external type II NAD(P)H dehydrogenases (DHs) of the NDB family, which are characterized by an EF-hand domain for Ca2+ binding. Here we investigate these pla

CNTN6 mutations are risk factors for abnormal auditory sensory perception in autism spectrum disorders

Contactin genes CNTN5 and CNTN6 code for neuronal cell adhesion molecules that promote neurite outgrowth in sensory-motor neuronal pathways. Mutations of CNTN5 and CNTN6 have previously been reported in individuals with autism spectrum disorders (ASDs), but very little is known on their prevalence and clinical impact. In this study, we identified CNTN5 and CNTN6 deleteriousvariants in individuals

Body mass index and suicide methods

Overweight and obesity is associated with lower rates of suicide. However, little is known about the association with different suicide methods. We studied the association between groups of body mass index and suicide methods. We identified all medicolegal autopsy cases with a cause of death due to external causes in Sweden during 1999-2013 (N = 39,368) and included 11,715 suicides and 13,316 acci

Intraspecific variation in migratory pattern of a partial migrant, the Blue Tit (Parus caeruleus) : An evaluation of different hypotheses

To evaluate hypotheses explaining intraspecific variation in migratory behavior in partial migrants, a local population of Blue Tits (Parus caeruleus) was studied in southern Sweden. Birds born in the study area and recaptured there in winter were compared with birds recaptured at a nearby bird station where a large number of migrant Blue Tits were passing. By comparing sex ratios among migrants a

Slow-light-based optical frequency shifter

We demonstrate experimentally and theoretically a controllable way of shifting the frequency of an optical pulse by using a combination of spectral hole burning, slow light effect, and linear Stark effect in a rare-earth-ion-doped crystal. We claim that the solid angle of acceptance of a frequency shift structure can be close to 2π, which means that the frequency shifter could work not only for op

6;7 chromosomal translocation in spontaneously arising rat immunocytomas : evidence for c-myc breakpoint clustering and correlation between isotypic expression and the c-myc target

Our previous studies have shown that spontaneously arising immunocytomas in the LOU/Ws1 strain of rats contain a t(6;7) chromosomal translocation in all seven tumors studied (F. M. Babonits, J. Spira, G. Klein, and H. Bazin, Int. J. Cancer 29:431-437, 1982). We have also shown that the c-myc is located on chromosome 7 (J. Sümegi, J. Spira, H. Bazin, J. Szpirer, G. Levan, and G. Klein, Nature (Lond

SLF:s höstexkursion längs Indalsälven 12–13 september 2015

Andra helgen i september var det dags för SLF att ta en tur längs Indalsälven. Elfenbenslav, trådbrosklav och grynig påskrislav stod på programmet och vi var också sugna på att ta en ordentlig titt på stenarna i den torrlagda älvfåran i Döda fallets naturreservat. 11 deltagare träffades på vandrarhemmet i Liden för höstens lavexkursion.