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Molecular Characterization of Male Breast Cancer

Popular Abstract in Swedish Bröstcancer är den vanligaste cancerformen hos kvinnor i Sverige, men även män kan drabbas. Hos män är det dock en mycket ovanlig cancerform. I Sverige insjuknar cirka 40 män per år av bröstcancer jämfört med cirka 8000 kvinnor per år. Bröstcancer hos män och kvinnor är på många sätt lika. Till exempel är sjukdomstecknen desamma och visar sig oftast som en knöl eller knCancer is today a major healthcare problem worldwide. There are many forms of cancer, which is a genetic disease, believed to result from a multistep process with genetic and epigenetic changes accumulating over time. Breast cancer is one of the most common forms of cancer in women, while it is much more rare in men. Male breast cancer (MBC) exhibits both similarities and differences with female b

The final moments of landing in bumblebees, Bombus terrestris.

In comparison to other insects, like honeybees, bumblebees are very effective pollinators. Even though landing is a crucial part of pollination, little is known about how bumblebees orchestrate the final, critical moments of landing. Here, we use high-speed recordings to capture the fine details of the landing behaviour of free-flying bumblebees (Bombus terrestris), while landing on a flat platfor

ADHD bör uppmärksammas mer - tidiga insatser spar lidande.

ADHD is a common neurodevelopmental/neuropsychiatric disorder affecting about 5 percent of children. About 2-3 percent meet diagnostic criteria in adulthood as well. The core symptoms include inattention with or without hyperactivity/restlessness and impulsivity. The main cognitive deficit involves executive functions, probably related to a weak reward system. Symptoms will affect daily functionin

Proximates - A Social Context Engine

Several studies have shown the value of using proximity data to understand the social context of users. To simplify the use of social context in application development we have developed Proximates, a social context engine for mobile phones. It scans nearby Bluetooth peers to determine what devices are in proximity. We map Bluetooth MAC ids to user identities on existing social networks which then

Molecular mechanisms and complete antigen formation in allergic contact dermatitis

Allergic contact dermatitis (ACD) is a common T cell mediated skin disease. Small reactive organic molecules called haptens induce ACD. Haptens are not recognized by themselves, but need to bond to endogenous proteins in the skin, and processed further into complete antigens. Antigen specific T cells then recognize the resulting antigen. Although the haptens are well known, the chemical reactions

Environmental assessment of propionic acid produced in an agricultural biomass-based biorefinery system

This paper presents an environmental system study of the production of propionic acid in a biorefinery system based on agricultural by-products. Here, propionic acid is produced by fermentation of glycerol, a by-product from biodiesel production, as carbon source and potato juice, a by-product from starch production, as nitrogen source. Biomass-based propionic acid leads to a greenhouse gas reduct

Isolation of xylose isomerases by sequence- and function-based screening from a soil metagenomic library

Background: Xylose isomerase (XI) catalyses the isomerisation of xylose to xylulose in bacteria and some fungi. Currently, only a limited number of XI genes have been functionally expressed in Saccharomyces cerevisiae, the microorganism of choice for lignocellulosic ethanol production. The objective of the present study was to search for novel XI genes in the vastly diverse microbial habitat prese

The planet search programme at the ESO CES and HARPS IV. The search for Jupiter analogues around solar-like stars

Context. In 1992 we began a precision radial velocity survey for planets around solar-like stars with the Coude Echelle Spectrograph and the Long Camera (CES LC) at the 1.4m telescope in La Silla (Chile) resulting in the discovery of the planet iota Hor b. We have continued the survey with the upgraded CES Very Long Camera (VLC) and the HARPS spectrographs, both at the 3.6m telescope, until 2007.

Dissolution state of cellulose in aqueous systems. 1. Alkaline solvents

The understanding of the state of dissolution of cellulose in a certain solvent is a critical step forward in the development of new efficient solvent systems for cellulose. Nevertheless, obtaining such information is not trivial. Recently, polarization transfer solid-state NMR (PTssNMR) was shown to be a very promising technique regarding an efficient and robust characterization of the solution s

Molecular composition and ultrastructure of Jurassic paravian feathers.

Feathers are amongst the most complex epidermal structures known, and they have a well-documented evolutionary trajectory across non-avian dinosaurs and basal birds. Moreover, melanosome-like microbodies preserved in association with fossil plumage have been used to reconstruct original colour, behaviour and physiology. However, these putative ancient melanosomes might alternatively represent micr

Sitting and standing performance in a total population of children with cerebral palsy: a cross-sectional study

Background: Knowledge of sitting and standing performance in a total population of children with cerebral palsy (CP) is of interest for health care planning and for prediction of future ability in the individual child. In 1994, a register and a health care programme for children with CP in southern Sweden was initiated. In the programme information on how the child usually sits, stands, stands up

Synchronization of Networks of Heterogeneous Agents With Common Nominal Behavior

This paper deals with the problem of synchronization in networks of heterogeneous agents with common nominal behavior. The agents are modeled as (possibly nonlinear) perturbed versions of a common SISO nominal LTI operator, and they are interconnected via a sparse memoryless interconnection operator, coherent with the communication graph underlying the network. The network is said to synchronize i

ASTROMETRIC EXOPLANET DETECTION WITH GAIA

We provide a revised assessment of the number of exoplanets that should be discovered by Gaia astrometry, extending previous studies to a broader range of spectral types, distances, and magnitudes. Our assessment is based on a large representative sample of host stars from the TRILEGAL Galaxy population synthesis model, recent estimates of the exoplanet frequency distributions as a function of ste