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The gut bacterial community affects immunity but not metabolism in a specialist herbivorous butterfly

Plant tissues often lack essential nutritive elements and may contain a range of secondary toxic compounds. As nutritional imbalance in food intake may affect the performances of herbivores, the latter have evolved a variety of physiological mechanisms to cope with the challenges of digesting their plant-based diet. Some of these strategies involve living in association with symbiotic microbes tha

RIFM fragrance ingredient safety assessment, decanoic acid, CAS Registry Number 334-48-5

The existing information supports the use of this material as described in this safety assessment. Decanoic acid was evaluated for genotoxicity, repeated dose toxicity, reproductive toxicity, local respiratory toxicity, phototoxicity/photoallergenicity, skin sensitization, and environmental safety. Data on the target material and from read-across analog nonanoic acid (CAS # 112-05-0) show that dec

Characterisation of nystagmus waveforms in eye-tracker signals

This thesis deals with the analysis of eye–tracker signals recorded from nystagmus patients. Nystagmus is an eye movement disorder caused by an underlying condition, and patients who suffer from nystagmus express involuntary oscillating eye move- ments. The oscillatory patterns expressed by these patiens are typically linked to the underlying condition, but it is usually difficult to precisely dia

Taking a Deep Breath : an Examination of Current Controversies in Surgical Procedures in Lung Transplantation

Purpose of Review: This article reviews controversial questions within the field of lung transplantation, with a focus on data generated within the last 3 years. We aim to summarize differing opinions on a selection of topics, including bridge-to-transplantation, intraoperative machine circulatory support, bronchial anastomosis, size mismatch, delayed chest closure, and ex vivo lung perfusion.Rece

Television Adaptations of Jane Austen’s Emma, 1972–2009

The aim of this paper was to analyse how three different television adaptations of Jane Austen’s Emma(1815) avail themselves of the medium of television to narrate the story. The productions analysed are John Glenister’s BBC series from 1972, dramatised by Denis Constanduros; Diarmuid Lawrence’s ITV film from 1996, dramatised by Andrew Davies; and Jim O’Hanlon’s BBC series from 2009, dramatised by

Salinomycin treatment specifically inhibits cell proliferation of cancer stem cells revealed by longitudinal single cell tracking in combination with fluorescence microscopy

A cell line derived from a tumor is a heterogeneous mixture of phenotypically different cells. Such cancer cell lines are used extensively in the search for new anticancer drugs and for investigating their mechanisms of action. Most studies today are population-based, implying that small subpopulations of cells, reacting differently to the potential drug go undetected. This is a problem specifical

Outside in : Roles of complement in autophagy

The complement system is a well-characterized cascade of extracellular serum proteins that is activated by pathogens and unwanted waste material. Products of activated complement signal to the host cells via cell surface receptors, eliciting responses such as removal of the stimulus by phagocytosis. The complement system therefore functions as a warning system, resulting in removal of unwanted mat

Expression and Purification of Intrinsically Disordered Aβ Peptide and Setup of Reproducible Aggregation Kinetics Experiment

High purity and sequence homogeneity of intrinsically disordered proteins are prerequisites for reproducible studies of the kinetics and equilibrium of their self-assembly reactions. Starting from the pure state enables quantitative studies of intrinsic and extrinsic factors in the process to understand its molecular determinants. Here we outline detailed protocols for recombinant expression and p

Target Tracking using Signal Strength Differences for Long-Range IoT Networks

Radio based positioning or tracking solutions typically require wideband signals or phase coherent antennas. In this paper, we present a target tracking method based on received non-coherent signal strength differences (RSSDs) between antennas for outdoor Internet-of-things (IoT) scenarios. We introduce an RSSD model based on classical path-loss models. With known antenna patterns and antenna arra

Chasing PtOx species in ceria supported platinum during CO oxidation extinction with correlative operando spectroscopic techniques

Industrially relevant, highly dispersed, Pt/ceria and reference Pt/alumina catalysts with narrow Pt particle size distributions have been prepared, characterised ex situ and studied for CO oxidation by operando infrared and X-ray absorption spectroscopy. At high CO conversions, spectator CO ad-species on ionic platinum are observed while the CO oxidation proceeds on Pt particles in a high oxidatio

Relationship between somatostatin receptor expressing tumour volume and health-related quality of life in patients with metastatic GEP-NET

For patients with gastroenteropancreatic neuroendocrine tumours (GEP-NET), health-related quality of life (HRQoL) is important. Meanwhile, whether tumour volume is associated with HRQoL is unknown. Hence, the aim of this study was to assess if total somatostatin receptor expressing tumour volume is correlated with HRQoL in patients with metastatic GEP-NET. Some 71 patients were included in the stu

Secretory granule exocytosis and its amplification by cAMP in pancreatic β-cells

The sequence of events for secreting insulin in response to glucose in pancreatic β-cells is termed “stimulus-secretion coupling”. The core of stimulus-secretion coupling is a process which generates electrical activity in response to glucose uptake and causes Ca2+ oscillation for triggering exocytosis of insulin-containing secretory granules. Prior to exocytosis, the secretory granules are mobili

Tower Houses in Medieval Scanian Towns

Towers in medieval towns is something normally connected to southern Europe. In Scandinavia, towers are seen as something belonging to castles and residences in the countryside, not to urban milieus. However, they are to be found even in Scandinavian towns. In this paper the existence of private urban tower houses in medieval Scania will be presented and discussed, and a hypothesis about a previou