The type and potency of an immune response provoked during vaccination will determine ultimate success in disease prevention. The basis for this response will be the design and implementation of antigen presentation to the immune system. Whereas direct antigen administration will elicit some form of immunological response, a more sophisticated approach would couple the antigen of interest to a vec

In this paper we report some results of our numerical simulations of sprays in compressible flows using Large Eddy Simulation. The combined LES- and spray code has been applied to the computation of the flow and spray injection into a swirl generator of a gas-turbine. The interaction between the spray jet and the flow field has been investigated. A dynamic SGS model has been used and results have

A high order Cartesian grid method is developed and applied to large eddy simulations (LES) of isothermal and reactive turbulent flows. Cartesian grid methods are potentially the most suitable numerical methods for LES because of its economical storage requirement, less computational effort per computational cell, fast numerical convergence and feasibility for constructing higher order finite diff

Children of immigrants inherit human capital attainment from their parents that impact on their innovative performance. Some of this stem from their migrant parents’ positive and negative selection traits, part from their physical or cognitive proximity of country of origin to the host society. In this paper, I examine how second-generation immigrants (with at least one foreign-born parent), takin

Hypothesis The adsorbed amount of the polyelectrolyte-like protein histatin 5 on a silica surface depends on the pH and the ionic strength of the solution. Interestingly, an increase in ionic strength affects the adsorbed amount differently depending on the pH of the solution, as shown by ellipsometry measurements (Hyltegren, 2016). We have tested the hypothesis that the same (qualitative) trends

Pyranose Dehydrogenase 1 from the basidiomycete Agaricus meleagris (AmPDH1) is an oxidoreductase capable of oxidizing a broad variety of sugars. Due to this and its ability of dioxidation of substrates and no side production of hydrogen peroxide, it is studied for use in enzymatic bio-fuel cells. In-vitro deglycosylated AmPDH1 as well as knock-out mutants of the N-glycosylation sites N75 and N175,

Powerful analytical tools are vital for characterizing the complex molecular changes underlying oncogenesis and cancer treatment. This is particularly true, if information is to be collected in vivo by noninvasive approaches. In the recent past, hyperpolarized (13)C magnetic resonance (MR) spectroscopy has been employed to quickly collect detailed spectral information on the chemical fate of trace

The generation of new mobile devices and the need to make decisions 'on the move' led to a new technology coined as mobile business intelligence (m-BI). M-BI is different from traditional BI in terms of user profiles, level of analytics and functionalities. Although there is a growing interest from both practitioners and academics, very little is known about m-BI in general and even less on its us

Over the past few years, a growing body of work in economic geography and innovation studies has enhanced our understanding of forms and determinants of regional industrial path development. The importance of policy, however, has received limited attention and accordingly, the role of policy for the emergence and development of new regional industrial growth paths remains largely unexplored. This

We have all experienced how a telephone conversation can be more challenging than speaking face to face. Understanding the intended meaning of a speaker‘s words requires forming an impression of the current mental state of the speaker, including her beliefs, intentions, and emotional state (Sperber & Wilson, 1995). Facial expressions are an important source of this information. In this study,