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Nucleotide metabolism and replication of nucleic acids are processes of fundamental importance. A crucial enzyme in nucleotide metabolism is dUTPase (E.C. 3.6.1.23), that catalyses the hydrolysis of dUTP to dUMP and pyrophosphate. The activity of the enzyme has influence on the outcome of DNA replication and complete loss of enzyme activity is lethal, while a decreased activity promotes increased

In this paper we estimate the level and inequality of income for Bechuanaland Protectorate by constructing four social tables between 1936 to 1964 using colonial archives and anthropological records. We present a working hypothesis that there is need to further analyze Botswana’s colonial era if we are to understand several aspects of contemporary economic structures. Our focus is on identifying t

In this paper we present an analysis of the effects of antenna placement on the radio channel properties for Vehicle-to-Vehicle communications based on measurements performed in three different propagation scenarios; highway, urban and rural. Four omni-directional antennas were mounted at four different positions: roof, bumper, left-side mirror and inside windscreen of two standard station wagons

Popular Abstract in Swedish Denna avhandling handlar om antikroppar. Antikroppar är proteiner som bildas av vårt immunförsvar för att skydda oss mot farliga ämnen i vår omgivning, som tex bakterier. På grund av antikroppars unika uppbyggnad och funktion utnyttjas ofta dessa på konstgjord väg. De kan injiceras i kroppen för att bota någon sjukdom eller användas på laboratoriet i olika analyser. InnIn vitro generation of antibody fragments of desired specificity and affinity plays an important role since it permits the generation of reagents which may be valuable for diagnostic and therapeutic applications. Furthermore, the kinetic parameters for an antibody-antigen interaction, rather than the affinity, has shown to correlate with biological functions like virus neutralization. This points

Popular Abstract in Undetermined Denne afhandling præsenterer en ny udlæsnings metode udviklet til cantileverbaserede sensorer. Cantilevere er tynde vipper, der er fastgjorte i den ene ende, og som igennem de seneste ti °ar har vist sig at være en interessant ny type bio/kemisk sensor. Den specifikke genkendelse af et kemikalie viser sig ved at cantileveren bøjer som følge af det skabte overfladesThis thesis presents a novel read-out method developed for cantilever-based sensors. Cantilevers are thin beams clamped at one end and during the last 10 years they have emerged as an interesting new type of bio/chemical sensor. The specific recognition of a chemical manifests itself as a bending of the cantilever from the generated surface stress. Conventionally the read-out used for this type of

Many modern office buildings have highly glazed facades. Their energy efficiency and indoor climate is, however, being questioned. Therefore more and more of these buildings are being built with double skin facades, which can provide improvements: a thermal buffer zone, energy savings, wind protection with open windows, fire protection, aesthetics, solar preheating of ventilation air, sound protec

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