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Androgen deprivation therapy (ADT) with gonadotropin-releasing hormone (GnRH) agonists and antagonists is the mainstay of advanced prostate cancer treatment. Both drug classes decrease levels of luteinizing hormone and follicle-stimulating hormones (FSH), thereby lowering testosterone to castrate levels. This is associated with adverse events (AEs), including cardiovascular (CV) disorders, bone fr
Objectives: To explore the preoperative, intraoperative, and postoperative dynamics of heparin-binding protein (HBP) in cardiothoracic surgery. Design: This was a prospective, observational study. Setting: The study was conducted at a single university hospital. Participants: Thirty patients undergoing cardiac surgery with cardiopulmonary bypass (CPB) were included, 15 of whom underwent coronary a
The relative role of natural selection and genetic drift in evolution is a major topic of debate in evolutionary biology. Most knowledge spring from a small group of organisms and originate from before it was possible to generate genome-wide data on genetic variation. Hence, it is necessary to extend to a larger number of taxonomic groups, descriptive and hypothesis-based research aiming at unders
Genome scans in recently separated species can inform on molecular mechanisms and evolutionary processes driving divergence. Large-scale polymorphism data from multiple species pairs are also key to investigate the repeatability of divergence-whether radiations tend to show parallel responses to similar selection pressures and/or underlying molecular forces. Here, we used whole-genome resequencing
The Christian monastic tradition has its origins in the Middle East. It has been and remains a constitutive institution in the Oriental Orthodox Churches, which are the Armenian, Coptic, Ethiopian, and Syrian Orthodox Churches. In Armenia, Egypt, Ethiopia, and the Syriac-speaking Christian traditions, the monasteries have been the most important educational institutions in which language and liter
On the basis of a critical survey of university strategies, it is argued that universities reify and objectify “world class” and turn it into absolute and precisely defined goals (location in ranking hierarchies, publication patterns, number of start-ups and licens-es, etc.) and that this in turn is based on a skewed reading of the ascendancy of some universities (notably leading US higher educati
En betongkonstruktion som skadas av alkalikiselreaktioner spricker, förlorar sin hållfasthet, och blir utsatt för andra typer av nedbrytningsprocesser som frostangrepp och urlakning. Syftet med denna sammanställning är att vägleda och sprida kunskap om olika materialmodeller som kan användas för analys av utveckling av skador som orsakas av alkalikiselreaktioner i betongkonstruktioner. Kunskapen k
Mönster i grönt undersöker sambanden mellan receptionen av Graham Greenes verk och 1900-talslitteraturens villkor, med särskilt hänseende till genremässiga och mediala hierarkier på den internationella bokmarknaden. Studien visar att komplexiteten i Greenes litteraturhistoriska position – där omfattningen och den internationella spridningen av hans verk lett till ett slags frikoppling från enskild
Aggregates cytotoxie for human cells in vitro were produced when adenovirus type 5 was mixed with homotypic rabbit antiserum against whole virus particles at a certain restricted virus-antibody ratio. The same degree of cytotoxicity was obtained with mixtures of the virus and an antiserum against purified fibres of adenovirus type 5 at a certain proportion. The cytotoxicity could be neutralized by
The cumulative incidence of tumours was registered in CBA mice inoculated with adenovirus type 12 when newborn and treated with BCG in different ways during the latency period. A single subcutaneous dose of BCG at 3–4 weeks of age had a preventive effect, while no prevention could be recorded after a single BCG dose at 9 weeks of age or eight BCG injections at intervals of 1 week. Sera obtained du
Hyperimmune mouse antisera against syngeneic adenovirus type 12 induced tumors and their 7 S and 19 S fractions of immunoglobulins obtained after combined diethylaminoethyl cellulose and Sephadex G-200 separation were tested against a rat adenovirus type 12 induced tumor by 51 Cr release technique. The same sera and their fractions were investigated with the colony inhibition technique for ability
In this paper I present two normative standpoints that have been used to de ne and evaluate human decision making: ’economic man’ and ’ecological rationality’. I argue that both norms are unsuitable to understand decision making in a natural environment. I do so by trying to apply them to a real-life decision situation; that of buying pasta in a Swedish supermarket. Neither account is su ciently f
I en bok om det skapelseteologiska arvet idag undersöker jag i ett kapitel predikans profetiska potential. Jag presenterar vad profetisk predikan är enligt framförallt Walter Brueggemann och Leonora Tubbs Tisdale. Jag presenterar också Gustaf Wingrens syn på predikan och för sedan dessa i dialog med varandra. Kapitlet mynnar ut i en fråga om hur kyrkan kan vara profetisk och samtidigt folkkyrkligt
In the literature on Swedish labour market history, it is commonly accepted (Westerståhl 1945, Nycander 2008) that the Swedish state in the late nineteenth and early twentieth centuries was unique in its abstention from anti-union, anti-strike policy. While in other European countries the conflict between employers and workers led to state repression of unions and strikes, the Swedish state was ne
