Objective. To investigate the relationship between PTEN gene expression and differentiation of glioma. Material and methods. The quantitative real-time reverse transcription-polymerase chain reaction (RT-PCR) method was applied to detect PTEN mRNA levels in glioma tissues. Tumor-adjacent normal tissues and benign brain tumors were used as controls. Relative PTEN mRNA levels were determined as the

Luthers kombination av Guds-ords-mystik och kallelsemedvetande blir så tydlig att den just därför varit svår att förstå. Stolt gör upp med vanföreställningar som att retorik skulle utesluta spontanitet. Hon utgår från språkvetenskapliga iakttagelser: Luthers latinska och tyska språkanvändning står i intensivt beroende av varandra, och hans nyskapande insatser för det tyska språket kan inte isolera

Twenty-one boys (age range 5 months to 16 years) were followed during their stay at hospital. Total observation time was 120 h. Field notes were made immediately after each observation. These were then transcribed into a narrative text, which was analysed by content analysis. Six categories of needs were identified during non-threatening situations at the hospital: the need for activity, the need

This working paper on Tongan names for plants and animals is intended as a contribution to the documentation of environmental knowledge in one of the most traditional societies of Polynesia. The list contains over 1 400 folk taxa: seaweeds 18 names, terrestrial plants 801 names, marine invertebrates 203 names, terrestrial invertebrates 72 names, fishes 231 names, reptiles and amphibians 15 names,

The Swedish auxiliary "lär" may have been established at the end of the 15th century in Swedish. Its two possible origins are discussed from phonological, morphological and semantic aspects. Possible stages in its develpment are identified and discussed as cases of grammaticalization.

The evolution of human immunodeficiency virus type 1 (HIV-1) coreceptor use has been described as the acquisition of CXCR4 use linked to accelerated disease progression. However, CXCR4-using virus can be isolated only from approximately one-half of individuals with progressive HIV-1 disease. The other half continue to yield only CCR5-using viruses (R5 phenotype) throughout the course of disease. I

Purpose of review To examine the development of recombinant FVIIa (rFVIIa); a new concept of inducing hemostasis. It was developed for use in hemophilia patients with inhibitors against FVIII or FIX with the vision to provide these patients with a therapeutical option to be used instead of FVIII or FIX. For the first time it was shown that pharmacological doses of FVIIa induced hemostasis. Recent

Popular Abstract in Swedish Respiratorbehandling i hemmet till patienter med kronisk underventilering (som kan bero på flera olika grundsjukdomar) har blivit allmänt accepterad, eftersom behandlingen kan ge symptomlindring och förbättrad överlevnad. Syfte: Att undersöka vilka behandlingsmotiv som föranleder start av respiratorbehandling i hemmet och att kvantifiera effekterna av behandlingen på pHome mechanical ventilation in patients with chronic respiratory failure secondary to several different diseases has become widely acceptable as the provision of ventilatory support can provide symptomatic relief and increase life expectancy. Aims: To study the selection criteria underlying the initiation of home mechanical ventilation and to quantify the effects of in relation to blood gases and

The recycling heparan sulfate (HS)-containing proteoglycan glypican-1 (Gpc-1) is processed by nitric oxide (NO)-catalyzed deaminative cleavage of its HS chains at N-unsubstituted glucosamines. This generates anhydromannose (anMan)-containing HS degradation products that can be detected by a specific antibody. Here we have attempted to identify the intracellular compartments where these products ar

Context: Previous in vitro studies have demonstrated that the UDP glucuronosyltransferase (UGT) 2B15 and UGT2B17 glucuronidate androgens and their metabolites. Objective: Our objective was to determine in vivo whether the UGT2B15 (DY)-Y-85 and the UGT2B17 deletion polymorphisms predict androgen glucuronidation and body composition. Participants: Two population-based cohorts including young adult (

Aquaporins are water channel proteins that facilitate the movement of water and other small solutes across biological membranes. Plants usually have large aquaporin families, providing them with many ways to regulate the water transport. Some aquaporins are regulated post-translationally by phosphorylation. We have previously shown that the water channel activity of SoP1P2;1, an aquaporin in the p