The article discusses the impact of comparative/historical philology upon the question of nuclear semiotics, i.e. the field of how humanity is to communicate information about nuclear waste storage into the distant future and its (presumably human) inhabitants. It also turns this perspective on its head and discusses possible insights in the other direction – what Nuclear Semiotics can teach histo

Objective. To analyse the management of muscle-invasive bladder cancer in a population-based national register, and specifically to investigate the role of curative therapy (i.e. cystectomy or radiotherapy) in relation to patient, tumour and hospital characteristics. Material and methods. The Swedish Bladder Cancer Register covers more than 90% of all patients in the country who have been diagnose

Selective immunoglobulin A deficiency (IgAD) is the most common primary immunodeficiency in Caucasians. It has previously been suggested to be associated with a variety of concomitant autoimmune diseases. In this review, we present data on the prevalence of IgAD in patients with Graves disease (GD), systemic lupus erythematosus (SLE), type 1 diabetes (T1D). celiac disease (CD), myasthenia gravis (

Several studies have proposed aerobic methane (CH4) emissions by plants. If confirmed, these findings would further increase the imbalance in the global CH4 budget which today underestimates CH4 sinks. Oxidation by OH-radicals in the troposphere is the major identified sink followed by smaller contribution from stratospheric loss and oxidation by methano- and methylotrophic bacteria in soils. This

This dissertation deals with antique warfare in general and late Roman warfare in particular. The overall aim is to discuss the concept of strategy in the archaeological and historical reconstruction, based on Edward N. Luttwak’s groundbreaking work The Grand Strategy of the Roman Empire (1976). Luttwak’s influence on various provincial Roman research fields cannot be underestimated, but the book

We study a generalized Pólya urn model with two types of ball. If the drawn ball is red, it is replaced together with a black ball, but if the drawn ball is black it is replaced and a red ball is thrown out of the urn. When only black balls remain, the roles of the colors are swapped and the process restarts. We prove that the resulting Markov chain is transient but that if we throw out a ball eve

Aerobic granular sludge has a number of advantages over conventional activated sludge flocs, such as cohesive and strong matrix, fast settling characteristic, high biomass retention and ability to withstand high organic loadings, all aspects leading towards a compact reactor system. Still there are very few studies on the strength of aerobic granules. A procedure that has been used previously for

Objectives: Autoimmune diseases such as rheumatoid arthritis (RA) and multiple sclerosis (MS) affect a relatively large portion of the population, leading to severe disability if left untreated. Even though pharmaceutics targeting the immune system have revolutionised the therapy of these diseases, there is still a need for novel, more effective therapeutic substances. One such substance is the ne

Most econometric methods for testing the proposition of long-run monetary neutrality rely on the assumption that money and real output do not cointegrate, a result that is usually supported by the data. This paper argues that these results can be attributed in part to the low power of univariate tests, and that a violation of the noncointegration assumption is likely to result in a nonrejection of

Background: Both insulin and thiazolidinediones (TZDs) are effective in the treatment of hyperglycaemia and amelioration of insulin resistance in type 2 diabetes but have side effects including weight gain and fluid retention. The use of TZDs has been further hampered by the risk of adverse cardiovascular events including heart failure. The present study evaluated the effect of pioglitazone or ins

Due to large equilibrium fluctuations of protons at physiological pH, the orthophosphate ion as well as the imidazole group on histidine substantially regulate their charge upon approaching charged interfaces. This implies that these-and comparable-ions function as electostatic "proximity switches" when interacting with lipid membranes, DNA, proteins, etc. Using straightforward statistical thermod

Background: When performing functional and structural studies, large quantities of pure protein are desired. Most membrane proteins are however not abundantly expressed in their native tissues, which in general rules out purification from natural sources. Heterologous expression, especially of eukaryotic membrane proteins, has also proven to be challenging. The development of expression systems in

Background: Having friends is associated with more favourable clinical outcomes and a higher quality of life in mental disorders. Patients with schizophrenia have fewer friends than other mentally ill patients. No large scale studies have evaluated so far what symptom dimensions of schizophrenia are associated with the lack of friendships. Methods: Data from four multi-centre studies on outpatient

Popular Abstract in Swedish Wilms tumör eller nefroblastom är en njurtumör som drabbar 10-15 barn i Sverige varje år. Majoriteten av dessa är under sex år vid insjuknandet och 10 % av de som drabbas överlever inte sjukdomen. Tumören består oftast av tre stycken cellkomponenter: blastem, epitel och stroma. Dessa komponenter kan finnas av olika mängd i tumören. Om en tumör består av mer än 2/3 av nåThe aim of this thesis has been to establish biomarkers for the blastemal element in Wilms tumour (WT) – the most common paediatric kidney cancer. Blastema is, together with epithelium and stroma, one of the three common histological elements of WT. WTs dominated by blastema after preoperative chemotherapy are classified as high risk tumours. According to the SIOP2001 protocol used in most Europea