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New seeds, gender norms and labor dynamics in Hoima District, Uganda

NERICA, a new group of high-yielding and stress-tolerant upland rice varieties developed by the Africa Rice Center, is changing production strategies of many Ugandan households. This article contributes a better understanding of processes leading to NERICA-related household outcomes in Hoima District, Uganda, by examining patterns of intrahousehold production relations and their consequences for h

Constrained Multilinear Detection and Generalized Graph Motifs

We introduce a new algebraic sieving technique to detect constrained multilinear monomials in multivariate polynomial generating functions given by an evaluation oracle. The polynomials are assumed to have coefficients from a field of characteristic two. As applications of the technique, we show an O^∗(2^k)-time polynomial space algorithm for the k-sized Graph Motif problem. We also introduce a ne

Acceleration Feedback Control for Nonlinear Teleoperation Systems with Time Delays

A procedure for acceleration feedback control of the delayed nonlinear teleoperation system is proposed. The acceleration feedback is applied to the master controller, while in the slave side the position error plus nonlinear damping controller is used to guarantee the input-to-state stability (ISS) of the controlled system. The Lyapunov-Krasovskii methodology is applied to analyse the ISS of the

Testing the Feasibility of Using the ForSAFE-VEG Model to Map the Critical Load of Nitrogen to Protect Plant Biodiversity in the Rocky Mountains Region, USA

The ForSAFE-VEG model was used to estimate atmospheric nitrogen deposition and climate effects on soil chemistry and ground vegetation in alpine and subalpine zones of the northern and central Rocky Mountains region in the USA from 1750 to 2500. Model simulations for a generalized site illustrated how the critical load of atmospheric nitrogen deposition could be estimated to protect plant biodiver

Improved glucose regulation in type 2 diabetic patients with DPP-4 inhibitors: focus on alpha and beta cell function and lipid metabolism.

Inhibition of dipeptidyl peptidase-4 (DPP-4) is an established glucose-lowering strategy for the management of type 2 diabetes mellitus. DPP-4 inhibitors reduce both fasting and postprandial plasma glucose levels, resulting in reduced HbA1c with low risk for hypoglycaemia and weight gain. They act primarily by preventing inactivation of the incretin hormones glucose-dependent insulinotropic polype

Multiple myeloma and infections: a population-based study on 9253 multiple myeloma patients.

Infections are a major cause of morbidity and mortality in patients with multiple myeloma. To estimate the risk of bacterial and viral infections in multiple myeloma patients, we used population-based data from Sweden to identify all multiple myeloma patients (n=9 253) diagnosed from 1988 to 2004 with follow-up to 2007 and 34 931 matched controls. Cox proportional hazard models were used to estima

Glucagon-like peptide 1 (GLP-1) analogue combined with insulin reduces HbA1c and weight with low risk of hypoglycemia and high treatment satisfaction

Aims: To evaluate the effects of adding glucagon-like peptide-1 (GLP-1) analogue therapy to insulin on glycated hemoglobin (HbA1c), weight, insulin dosage, treatment satisfaction, and risk of hypoglycaemia. Methods: Type 2 diabetes patients with insulin therapy receiving a GLP-1 analogue at 4 Swedish centers were studied. Hypoglycemia was evaluated using glucometers and patient self-report. The Di

The Swedish Confederation for Professional Employees (TCO) and trust-based working time

Abstract in UndeterminedThis article aims to provide a historical perspective to the emergence of trust-based control systems in the workplace. These systems are often seen as a response to increasedflexibility requirements following the progress of digital technology, globalisationand an increased knowledge content in production. In contrary to this opinion, itis argued in the article that the ph

WNT3 involvement in human bladder exstrophy and cloaca development in zebrafish.

Bladder exstrophy, a severe congenital urological malformation when a child is born with an open urinary bladder, is the most common form of bladder exstrophy-epispadias complex (BEEC) with an incidence of 1:30.000 children of Caucasian descent. Recent studies suggest that WNT genes may contribute to the etiology of bladder exstrophy. Here, we evaluated WNT pathway genes in 20 bladder exstrophy pa

The neurophenomenology of neutral hypnosis.

INTRODUCTION: After a hypnotic induction, medium and highly hypnotizable individuals often report spontaneous alterations in various dimensions of consciousness. Few studies investigating these experiences have controlled for the inherent demands of specific hypnotic suggestions and fewer still have considered their dynamic properties and neural correlates. METHODS: We adopted a neurophenomeno

ESCRTs regulate amyloid precursor protein sorting in multivesicular bodies and intracellular beta amyloid accumulation.

Intracellular beta amyloid (Aβ) accumulation is a key feature of early Alzheimer's disease (AD) and precedes the appearance of Aβ in extracellular plaques. Aβ is generated through proteolytic processing of amyloid precursor protein (APP), but the intracellular site of Aβ production is unclear. APP has been localized to multivesicular endosomes/bodies (MVBs) where sorting of APP onto ILVs could pro

Ethical considerations in chimera research.

The development of human pluripotent stem cells has opened up the possibility to analyse the function of human cells and tissues in animal hosts, thus generating chimeras. Although such lines of research have great potential for both basic and translational science, they also raise unique ethical issues that must be considered.

Hearing difficulties, uptake, and outcomes of hearing aids in people 85 years of age

Objective: The aim of this study was to investigate self-reported hearing difficulties, uptake, and hearing-aid outcomes and their relationships to demographic, cognitive, psychosocial, and health variables in 85 year olds. Design and study sample: Three hundred and forty-six elderly adults participated in a survey that included questionnaires and home visits. Fifty-five percent of participants ad

The Avian Transcriptome Response to Malaria Infection.

Malaria parasites are highly virulent pathogens which infect a wide range of vertebrates. Despite their importance, the way different hosts control and suppress malaria infections remains poorly understood. With recent developments in next generation sequencing techniques, however, it is now possible to quantify the response of the entire transcriptome to infections. We experimentally infected Eur

A thiol functionalized cryogel as a solid phase for selective reduction of a cysteine residue in a recombinant human growth hormone variant.

Site selective chemical modification is a preferred method, employed to prolong the circulation half-life of biopharmaceuticals. Cysteines have been used as attachment point for such modification, however, to be susceptible for chemical modification the involved thiol must be in its reduced form. Proteins often contain disulfides, which aid to maintain their tertiary structure and therefore must r