Aim: To test the feasibility of a fully automated artificial intelligence-based method providing PET measures of prostate cancer (PCa). Methods: A convolutional neural network (CNN) was trained for automated measurements in 18F-choline (FCH) PET/CT scans obtained prior to radical prostatectomy (RP) in 45 patients with newly diagnosed PCa. Automated values were obtained for prostate volume, maximal

Cerebral pares (CP) är den vanligaste orsaken till motorisk funktionsnedsättning hos barn och ungdomar och årligen föds ca 200 barn med CP i Sverige. Symtomen vid CP varierar, men karaktäriseras av bland annat nedsatt rörelseförmåga och nedsatt förmåga att stabilisera kroppen. Nästan åtta av tio vuxna med CP besväras av korta och spända muskler, snedställda leder och smärta som påverkar deras funkBackgroundIndividuals with cerebral palsy (CP) have an increased risk for scoliosis, especially those with low gross motor function, affecting both quality of life and overall function. The aims were to increase the knowledge on the development of, and predictors for scoliosis and the use of spinal orthoses in individuals with CP, and also to evaluate the Caregiver Priorities and Child Health Inde

Mellan 1873 och 1924 ingick Sverige i en valutaunion tillsammans med Danmark och Norge – den skandinaviska myntunionen (SMU) byggd på den gemen- samma valutaenheten – kronan. Denna artikel belyser tillkomsten, effekterna och upplösningen av den skandinaviska myntunionen samt jämför den med EMU. Ett medlemskap i EMU kräver mer av ekonomisk och politisk anpassning än vad ett medlemskap i SMU gjorde

A distinguishing feature of the federative organization is the ownership relationship. The owners are simultaneously both the providers of risk capital and the main suppliers (or customers) in relation to the unit owned. In other words there is a double binding contractual relation between owners and owned. In this paper the effects of the double binding contract are discussed, as well as the part

AimsCan drug abuse (DA) be transmitted psychologically between adult siblings consistent with a social contagion model?MethodsWe followed Swedish sibling pairs born in 1932-1990 until one of them, sibling1 (S1), had a first DA registration. We then examined, using Cox regression, the hazard rate for a first registration for DA in sibling2 (S2) within 3 years of a first DA registration in S1 as a f

Through an analysis of the FDA’s approval of the controversial anti-influenza drug Relenza (zanamivir), we interrogate distinct social scientific theories of pharmaceutical regulation. We investigate why, despite internal negative opinions and an Advisory Committee’s non-approval recommendation, the FDA approved Relenza in the late 1990s. Based on a close reading of FDA documents, we show how agen

Purpose: The purpose of this study is to enhance the thermal performance in the labyrinth channel by different ribs shape. The labyrinth channel is a relatively new cooling structure to decrease the temperature near the trailing region of gas turbine. Design/methodology/approach: Based on the geometric similarity, a simplified geometric model is used. The k − ω turbulence model is used to close th

The study aim was to report survival and morbidity of all patients in Sweden with peritoneal mesothelioma treated with cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) as well as investigate whether the survival has increased on a population level since this treatment was nationalized 2011. Study data were collected from the Swedish HIPEC registry and the Swedish N

Purpose: The purpose of the study was to investigate if surface guided radiotherapy (SGRT) can decrease setup deviations for tangential and locoregional breast cancer patients compared to conventional laser-based setup (LBS). Materials and Methods: Both tangential (63 patients) and locoregional (76 patients) breast cancer patients were enrolled in this study. For LBS, the patients were positioned

In cities, land-use decisions made during planning processes determine the availability of ecosystem services fundamental to the wellbeing of urban population. Hence, the inclusion of ecosystem services in planning is essential to promote sustainable urban development. This article investigates to what extent ecosystem services are currently included in urban plans. The ultimate objective is to un

Cell replacement is currently being explored as a therapeutic approach for neurodegenerative disease. Using stem cells as a source, transplantable progenitors can now be generated under conditions compliant with clinical application in patients. In this study, we elucidate factors controlling target-appropriate innervation and circuitry integration of human embryonic stem cell (hESC)-derived graft

Modulated nanoparticle-coating surfaces were fabricated by an improved electrophoretic deposition technique in this study. Pool boiling experiments were studied for HFE-7200 on the modulated nanoparticle-coating surfaces, with a smooth surface and uniform coating surfaces as comparison. It was found that the present modulated coating surfaces can enhance the heat transfer coefficient and the criti

A 60 year old man developed steatorrhoea, weight loss, mild diabetes mellitus, labile hypertension and limb cramps. Raised plasma concentrations of catecholamines, particularly noradrenaline and a computed tomography-scan showing an adrenal tumour strongly suggested a pheochromocytoma. Adrenoreceptor blockade reversed the symptoms, decreased faecal fat, and increased duodenal trypsin to normal con

Gender equality is widely accepted as an important explanatory factor for the occurrence of intimate partner violence (IPV) against women. However, the relationship is not straightforward, as high country-level gender equality is not always associated with lower IPV prevalence. We apply ‘multilevel analysis of individual heterogeneity and discriminatory accuracy’ (MAIHDA) to (i) quantify the exten

Degradation of agricultural soils and forest resources are two pervasive challenges in rural landscapes of sub-Saharan Africa. Biochar-producing biomass gasification technologies attract evermore interest because these can empower small-scale farmers to produce energy and food more sustainably byimproving energy use efficiencies, lowering emissions and strengthening climate resilience. In order to

I decennier var juridiken ett mansdominerat område. Men i slutet av 1800-talet började även kvinnor studera juridik. De måste dock överkomma många hinder innan de fick praktisera den. Artikeln belyser några av de kvinnliga pionjärerna inom juridiken och deras livsöden.