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The semantics of the particle le in Mandarin Chinese has been hotly debated in both Chinese and non-Chinese linguistic literature in particular during the past 25 years. Le is a post verbal particle, which also occurs in sentence final position. This syntactic flexibility and the fact that the presence of le seems to render distinct default readings depending on its syntactic position has given ri

Aspecuality, temporality and modality: a relevance-theoretic analysisof some pragmatic markers in Mandarin Chinese It is generally agreed that in Mandarin Chinese, tense (at least absolute tense) is not expressedmorphologically but there is a number of verbal and sentence-final particles that express aspect and mood. These (in particular the aspectual ones) have been studied rather extensively thr

The precise characterization of femtosecond laser pulses is as challenging as their generation and a topic of intense research. Dispersion-scan (d-scan) [1] is a recently established technique where the spectrum of a nonlinear signal, e.g., second-harmonic generation (SHG), is measured as a function of dispersion applied to the pulse. The spectral phase of the pulse can then be retrieved from the

Tillgängliga forskningsresultat om samband mellan radikalisering, terrorism och psykisk ohälsa kan ännu inte användas som underlag för beslut om ändrade rutiner eller behandlingsmetoder i klinisk psykiatrisk verksamhet. De screening- och riskbedömningsverktyg som finns tillgängliga för kliniskt bruk går inte att använda inom psykiatrin utan att psykiatrins roll i det svenska samhäl-let allvarligt There is little evidence supporting the concept of mental illness as a part of, or reason behind radicalization towards violent extremism and terrorism. There is weak evidence that lone gunmen, particularly those involved in school shootings, may suffer from mental illness to a larger degree than the general population, whereas organized terrorist groups such as jihadists and right-wing extremists

Food law, and food labelling, establishes the rights of consumers to safe food and to accurate and honest information. Although food safety is at the core of food information, the broad principle of the food law is about telling the truth about products so that the consumer can make a choice about what they choose to eat. However, food law and labelling can also become a trade barrier and thus con

Many B-cell neoplasms are associated with autoimmune diseases (AIDs) but most evidence is based on a personal rather than a family history of AIDs. Here we calculated risks for non-Hodgkin lymphoma (NHL), Hodgkin lymphoma (HL) and multiple myeloma (MM) when family members were diagnosed with any of 44 different AIDs, or, independently, risk for AIDs when family members were diagnosed with a neopla

Formulaic language is a crucial component of language overall, and therefore merits the development of tests capable of yielding valid and reliable scores. However, the diverse nature of formulaic language poses challenges for test design. This chapter will critique existing tests of formulaic language and discuss principles for the development of future tests. Key issues include construct definit

Coronary artery disease (CAD) is a major cause of death and disability. Several diagnostic tests, such as myocardial perfusion scintigraphy (MPS), are accurate for the detection of CAD, as well as having prognostic value for the prediction of cardiovascular events. Nevertheless, the diagnostic and prognostic value of these tests should be cost-effective and should lead to improved clinical outcome

Aims To study the incidence and aetiology of sudden cardiac death (SCD) in 1- to 35-year-olds in Sweden from 2000 to 2010. Methods and results We used the database of the Swedish National Board of Forensic Medicine and the Swedish Cause of Death Registry and identified SCD cases by review of forensic files and death certificates. We identified 552 individuals with SCD in 1- to 35-year-olds; 156 (2

Knowledge concerning the normal aging of cerebral white matter will improve our understanding of abnormal changes in neurodegenerative diseases. The microstructural basis of white matter maturation and aging can be investigated using diffusion tensor imaging (DTI). Generally, diffusion anisotropy increases during childhood and adolescence followed by a decline in middle age. However, this process

Pelvic and paraaortic lymphadenectomy are standard procedures for staging of genital cancers but may also be indicated by other malignancies in the pelvis. The procedures are well suited for minimally invasive surgery and robot assistance may help generalize and standardize the procedures.Step by step surgical techniques for pelvic and paraaortic lymphadenectomy will be described.

Vid kronisk myeloisk leukemi har målstyrd, kontinuerlig behandling med tyrosinkinashämmare lett till dramatiskt förbättrad överlevnad. Efter ett flertal år uppnås djupt molekylärt svar hos ca 50 procent av patienterna; ca 50 procent av dem kan då avbryta behandlingen utan tecken på återfall. Kontinuerlig behandling med tyrosinkinashämmare kan ge långsiktiga biverkningar. Efter patentutgång för imaChronic myeloid leukemia - a model disease for targeted therapy Chronic myeloid leukemia (CML) pioneered as the first human malignancy linked to a specific cytogenetic aberration (the Philadelphia chromosome), which led the way to specific targeted therapies with imatinib (Glivec) and later tyrosine kinase inhibitors (TKI). Continuous TKI administration, blocking the oncogenic fusion protein Bcr-A

The purpose of this study is threefold; 1) to establish the current level of knowledge regarding cost-effectiveness of organ transplantation, 2) to identify knowledge gaps, and 3) to suggest a framework for future studies. A systematic literature review of economic evaluations of transplantations of solid organs was conducted in October 2010. Economic evaluations published since 2000 and reviews p