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Gene Expression Profiles in Human and Mouse Primary Cells Provide New Insights into the Differential Actions of Vitamin D-3 Metabolites

1 alpha,25-Dihydroxyvitamin D-3 (1 alpha,25(OH)(2)D-3) had earlier been regarded as the only active hormone. The newly identified actions of 25-hydroxyvitamin D-3 (25(OH)D-3) and 24R,25-dihydroxyvitamin D-3 (24R,25(OH)(2)D-3) broadened the vitamin D-3 endocrine system, however, the current data are fragmented and a systematic understanding is lacking. Here we performed the first systematic study o

A combined small- and wide-angle x-ray scattering detector for measurements on reactive systems

A detector with high dynamic range designed for combined small-and wide-angle x-ray scattering experiments has been developed. It allows measurements on single events and reactive systems, such as particle formation in flames and evaporation of levitating drops. The detector consists of 26 channels covering a region from 0.5 degrees to 60 degrees and it provides continuous monitoring of the sample

Assessment of soil salinization risks under irrigation with brackish water in semiarid Tunisia

The salinity problem is becoming increasingly widespread in arid countries. In semiarid Tunisia about 50% of the irrigated land is considered as highly sensitive to salinization. To avoid the risk of salinization, it is important to control the soil salinity and keep it below plant salinity tolerance thresholds. The objective of the present study was to provide farmers and rural development office

Characterization of GaSb nanowires grown by MOVPE

We report the growth and characterization of GaSb nanowires grown by MOVPE. The structural properties of the nanowires are investigated by the means of transmission electron microscopy, X-ray diffraction and single nanowire photoluminescence. The measurements confirm a high material quality in the GaSb nanowires. Also, a back-gated nanowire transistor structure is used to extract values for the po

Charge Dependence of Solvent-Mediated Intermolecular Coster-Kronig Decay Dynamics of Aqueous Ions.

The 2s and 2p photoelectron spectra have been measured for Na(+), Mg(2+), and Al(3+) ions in aqueous solution. In all cases, the 2s lines are significantly broader than the 2p features, which is attributed to a shorter lifetime of the respective 2s hole. Since intraionic Coster-Kronig decay channels from the (2s)(-1) state are closed for free Na(+), Mg(2+), and Al(3+) ions, this is evidence for an

Altered gene expression and ecological divergence in sibling allopolyploids of Dactylorhiza (Orchidaceae)

Background: Hybridization and polyploidy are potent forces that have regularly stimulated plant evolution and adaptation. Dactylorhiza majalis s.s., D. traunsteineri s.l. and D. ebudensis are three allopolyploid species of a polyploid complex formed through unidirectional (and, in the first two cases, recurrent) hybridization between the widespread diploids D. fuchsii and D. incarnata. Differing c

Key biosynthetic gene subfamily recruited for pheromone production prior to the extensive radiation of Lepidoptera

Background: Moths have evolved highly successful mating systems, relying on species-specific mixtures of sex pheromone components for long-distance mate communication. Acyl-CoA desaturases are key enzymes in the biosynthesis of these compounds and to a large extent they account for the great diversity of pheromone structures in Lepidoptera. A novel desaturase gene subfamily that displays Delta 11

Effects of supplemental winter feeding on House Sparrows (Passer domesticus) in relation to landscape structure and farming systems in southern Sweden

CapsuleHouse Sparrow (Passer domesticus) populations in south Swedish farmland are not affected by supplemental winter feeding, irrespective of agricultural landscape type or presence of animal husbandry, although winter populations declined more in mixed farmland and when farms contained animal husbandry. AimsTo investigate whether food limitation of House Sparrow population size during the winte

Narration and reading comprehension in Swedish children and adolescents with hearing impairment

Popular Abstract in Swedish Barn och ungdomar med hörselnedsättning har, i högre grad än jämnåriga kamrater utan hörselnedsättning, språkliga problem. Dessa problem märks när barnen gått några år i skolan och större krav ställs på deras läsförmåga och på deras förmåga att uttrycka sig i tal och skrift. Problemen kan yttra sig tidigt och på olika sätt, som svårigheter med att uttala och särskilja sThe aim of the present thesis was to explore reading comprehension and narration in children and adolescents with different degrees of hearing impairment (HI). In Study I, reading comprehension was investigated in 16 children with cochlear implants (CI), aged 7-13 years. Over 60% of the investigated children performed at the level of their hearing peers. Reading comprehension was better than expec

Ice cover alters the behavior and stress level of brown trout Salmo trutta

Surface ice in rivers and lakes buffers the thermal environment and provides overhead cover, protecting aquatic animals from terrestrial predators. We tested if surface ice influenced the behavior (swimming activity, aggressive encounters, and number of food items eaten) and stress level (coloration of eyes and body) of stream-living brown trout Salmo trutta at temperatures of 3-4 degrees C in ind

Kvalitetsmanual för brandtekniska analyser vid svenska kärntekniska anläggningar

The report provides guidance on how to assure quality in fire safety analysis reports. The primary focus is on analyses in nuclear power plants but the report can also be used for other applications as the information can be seen as generic. The report provides a procedure to follow and targets at analytical fire safety engineering analyses. The report assumes that the reader is familiar with the

Respirometric analysis of activated sludge models from palm oil mill effluent

Activated sludge models (ASMs) have been widely used as a basis for further model development in wastewater treatment processes. Values for parameters to be used are vital for the accuracy of the modeling approach. A continuous stirred tank reactor (CSTR), as open respirometer with continuous flow for 20 h is used in ASMs. The dissolved oxygen (DO) profile for 11 days was monitored. It was found t

Improving the indoor air quality by using a surface emissions trap

The surface emissions trap, an adsorption cloth developed for reducing emissions of volatile organic compounds and particulate matter from surfaces while allowing evaporation of moisture, was used to improve the indoor air quality of a school building with elevated air concentrations of 2-ethyl-1-hexanol. An improvement of the perceived air quality was noticed a few days after the device had been

Measuring perceived meaningfulness in day centres for persons with mental illness

Rationale: As support in leading a meaningful and active life, a person with mental illness is often given the opportunity to attend a day centre. However, few studies have investigated the meaningfulness perceived by the person visiting a day centre. For such a purpose, a self-report instrument was developed. Aims: To explore whether perceived meaningfulness, as expressed in the recently develope

Reduced Prevalence of Diabetic Ketoacidosis at Diagnosis of Type 1 Diabetes in Young Children Participating in Longitudinal Follow-Up

OBJECTIVE-Young children have an unacceptably high prevalence of diabetic ketoacidosis (DKA) at the clinical diagnosis of type I. diabetes. The aim of this study was to determine whether knowledge of genetic risk and close follow-up for development of islet autoantibodies through participation in The Environmental Determinants of Diabetes in the Young (TEDDY) study results in lower prevalence of D

Responsibility in the Supply Chain: Interorganisational management of environmental and social aspects in the supply chain - Case studies from the textile sector

This thesis is about the intersection between Corporate Social Responsibility and Supply Chain Management. I call this upstream CSR, the phenomenon that arises when an issue on a company’s CSR agenda becomes an issue for its sourcing and supply management operations. Upstream CSR as a phenomenon is not without controversies, but it also holds an important potential for reducing negative environm