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Development of Non-Linear Laser-Based Imaging Techniques for Diagnostics of Reactive Flows

Understanding reactive flows is crucial for advancing energy production, combustion efficiency, and plasma- assisted chemical processes. These systems often involve short-lived radicals and transient phenomena that require high-resolution, non-intrusive diagnostic techniques for accurate characterization. This thesis focuses on the development of advanced non-linear laser-based imaging methods to

Activation of the canonical Wnt pathway leads to loss of hematopoietic stem cell repopulation and multilineage differentiation block

Wnt signaling increases hematopoietic stem cell self-renewal and is activated in both myeloid and lymphoid malignancies, indicating involvement in both normal and malignant hematopoiesis. We report here activated canonical Wnt signaling in the hematopoietic system through conditional expression of a stable form of beta-catenin. This enforced expression led to hematopoietic failure associated with

Direct electron transfer between copper-containing proteins and electrodes

The electrochemistry of some copper-containing proteins and enzymes, viz. azurin, galactose oxidase, tyrosinase (catechol oxidase), and the "blue" multicopper oxidases (ascorbate oxidase, bilirubin oxidase, ceruloplasmin, laccase) is reviewed and discussed in conjunction with their basic biochemical and structural characteristics. It is shown that long-range electron transfer between these enzymes

A Randomized Clinical Trial of Prophylaxis in Children with Hemophilia A (the ESPRIT Study).

Background: Prevention of arthropathy is a major goal of hemophilia treatment. While studies in adults have demonstrated an impact of prophylaxis on the incidence of joint bleeds and patients' well-being in terms of improved quality of life (QoL), it is unclear whether or not prophylaxis influences the outcome and well-being perception of children with hemophilia. Objective: This randomized contro

A field study in dairy farms: thermal condition of feet

The study aimed to find out the problems connected with feet during work in cold loose housing barns in wintertime. 13 dairy farms and 20 workers were studied. Skin temperatures and subjective responses were collected, and at the end of a work period the subjects filled in a questionnaire about the workday. The foot skin temperatures were measured on dorsal foot and second toe. Most of the workers

Stability of typical patterns of subjective well–being in middle–aged Swedish women

Typical patterns of general subjective well-being (SWB) were searched for in a representative longitudinal sample of Swedish women (N = 272) at age 43 and 49. Cluster analysis at each age separately resulted in a six-cluster solution at both ages. The two solutions were similar, indicating structural stability across 6 years. Five of the six clusters also showed significant individual stability. A

Short-distance HLbL contributions to the muon g-2

The current 3.7σ discrepancy between the Standard Model prediction and the experimental value of the muon anomalous magnetic moment could be a hint for the existence of new physics. The hadronic light-by-light contribution is one of the pieces requiring improved precision on the theory side, and an important step is to derive short-distance constraints for this quantity containing four electromagn

A FUNCTIONAL VIEW REVEALS SUBSTANTIAL PREDICTABILITY OF POLLINATOR-MEDIATED SELECTION

A predictive understanding of adaptation to changing environments hinges on a mechanistic understanding of the extent and causes of variation in natural selection. Estimating variation in selection is difficult due to the complex relationships between phenotypic traits and fitness, and the uncertainty associated with individual selection estimates. Plant-pollinator interactions provide ideal syste

Mapping multi-dimensional variability in water stress strategies across temperate forests

Increasing water stress is emerging as a global phenomenon, and is anticipated to have a marked impact on forest function. The role of tree functional strategies is pivotal in regulating forest fitness and their ability to cope with water stress. However, how the functional strategies found at the tree or species level scale up to characterise forest communities and their variation across regions

Early-term Birth (37-38 Weeks) and Mortality in Young Adulthood.

BACKGROUND:: Early-term birth (gestational age, 37-38 weeks) has been associated with increased infant mortality relative to later-term birth, but mortality beyond infancy has not been studied. We examined the association between early-term birth and mortality through young adulthood. METHODS:: We conducted a national cohort study of 679,981 singleton births in Sweden in 1973-1979, followed up for