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Natural Products from Bryophytes : From Basic Biology to Biotechnological Applications

Natural products from plants have served mankind in a wide range of applications, such as medicines, perfumes, or flavoring agents. For this reason, synthesis, regulation and function of plant-derived chemicals, as well as the evolution of metabolic diversity, has attracted researchers all around the world. In particular, vascular plants have been subject to such analyses due to prevalent characte

Anti-Fibrotic Activity of an Antimicrobial Peptide in a Drosophila Model

Fibrotic lesions accompany several pathological conditions, including tumors. We show that expression of a dominant-active form of the Ras oncogene in Drosophila salivary glands (SGs) leads to redistribution of components of the basement membrane (BM) and fibrotic lesions. Similar to several types of mammalian fibrosis, the disturbed BM attracts clot components, including insect transglutaminase a

The CHA2DS2-VASc Score and Its Association with Long-Term Outcome in a Cardiac Resynchronization Therapy Population

Background: Cardiac resynchronization therapy (CRT) is commonly used in patients with heart failure and left ventricular dyssynchrony. Several scoring systems have been tested in order to predict long-term outcome. Although intended for use in patients with atrial fibrillation, we sought to assess the performance of the CHA2DS2-VASc score in a CRT population. Methods: Data on 796 consecutive CRT p

An LBM-based investigation of thermal buoyancy and arrangement angle on flow characteristics and heat transfer over four heated square cylinders

In this work, the effects of thermal buoyancy and rotation angle on the hydrodynamics and mixed convection heat transfer characteristics over four heated identical square cylinders placed in a parallel horizontal channel are numerically studied. For the flow field, the Lattice Boltzmann method (LBM) with multiple relaxation time collision operator (MRT) is implemented and the Bhatnagar-Gross-Ktook

Influence of age and sex on disease course and treatment in rheumatoid arthritis

Objective: More than 50% of patients with rheumatoid arthritis (RA) are >65 years at diagnosis. Age of onset and sex may influence the disease course, outcome and treatment. This study follows a large cohort of patients with early RA to assess contributions of age and sex to disease outcomes. Methods: Patients from the BARFOT cohort, n=2837 (68% women), were followed for eight years at predefined

The Impact of Terminal Mobility on the Performance of a Panel-Based Large Intelligent Surface

A Large Intelligent Surface (LIS) is a recently pro-posed concept that relies on the integration of a vast number of antenna-elements over an entire surface able to transmit and/or receive information, especially suitable for high speed indoor communications and massive internet of things (IoT) applications. In this paper, we study the impact of terminal mobility on the performance of a panel-base

Internet of Buoys : An Internet of Things Implementation at Sea

Internet of Things (IoT) applications are emerging in many different areas, including maritime environments. One of the applications in this area is the monitoring of buoys at sea. To realize wireless tracking of buoys, an accurate prediction of the path loss in an open-sea environment is essential. So far, channel measurements at sea have mainly been conducted with antennas placed a couple of met

How much credence does it take? Evidence on the trade-off between country-of-origin information and credence attributes for beef from a choice experiment in Sweden

Based on a discrete choice experiment with 336 consumers, this study investigated whether the consumer propensity to choose a simplified European Union (EU) vs. non-EU denomination of origin for beef, instead of a specific country-of-origin (COO) denomination, depends upon the amount and type of credence information provided to the individual. The likelihood of choosing the EU/non-EU denomination

Bleeding phenotype of patients with moderate haemophilia A and B assessed by thromboelastometry and thrombin generation

Introduction: Predicting the bleeding phenotype is crucial for the management of patients with moderate haemophilia. Global coagulation assays evaluate haemostasis more comprehensively than conventional methods. Aim: To explore global coagulation assays and the bleeding phenotype of patients with moderate haemophilia A (MHA) and B (MHB). Methods: The MoHem study is a cross-sectional, multicentre s

Using Referent Grammar (RG) in Computer Analysis, Generation and Translation of Sentences

The paper presents Referent Grammar (RG), a version of generalized phrase structure grammar. RG uses descriptive labels for defective categories (categories tacking a constituent) instead of slash expressions and needs no null (empty, zero) categories. RG uses both functional and categorial representations and the grammar rules, written in the Prolog DCG formalism, relate these two levels. The fun

Differential access to facilities for medical termination of pregnancy and delivery in India: A secondary analysis

IntroductionEmerging evidence suggests a difference in access to facilities for medical termination of pregnancy (MTP) and delivery among women in different regions of the country. However, we lack assessments at a large scale across all geographies. Our study aims to describe the percent contribution of private and public sectors in institutional deliveries and MTP in India.MethodsA secondary dat

Heparan sulfate synthesized by mouse embryonic stem cells deficient in NDST1 and NDST2 is 6-O-sulfated but contains no N-sulfate groups

Heparan sulfate structure differs significantly between various cell types and during different developmental stages. The diversity is created during biosynthesis by sulfotransferases, which add sulfate groups to the growing chain, and a C5-epimerase, which converts selected glucuronic acid residues to iduronic acid. All these modifications are believed to depend on initial glucosamine N-sulfation

Freely Generated Word Responses Analyzed With Artificial Intelligence Predict Self-Reported Symptoms of Depression, Anxiety, and Worry

Background: Question-based computational language assessments (QCLA) of mental health, based on self-reported and freely generated word responses and analyzed with artificial intelligence, is a potential complement to rating scales for identifying mental health issues. This study aimed to examine to what extent this method captures items related to the primary and secondary symptoms associated wit

Greece: A Procedural Defence of Democracy against the Golden Dawn

Greece not a militant democracy – Constitution rejects party bans – Challenge posed by neo-Nazi party Golden Dawn – Preference for a procedural approach – Not as passive as previously thought – Proactive use of regular law – Golden Dawn charged for being a criminal organisation disguised as a political party – Questions about the political timing of the trial – Importance of judiciary independence

Three-dimensional coherent x-ray diffraction imaging of ferroelastic domains in single CsPbBr3 perovskite nanoparticles

Metal halide perovskites attract significant interest due to their remarkable performance in optoelectronic devices. However, the gap in understanding the relationship between their nanoscale structure and properties limits their application towards novel devices. In this work, twinned ferroelastic domains in single 500 nm CsPbBr3 particles are studied with 3D Bragg coherent x-ray diffraction imag

Svensk språkforskning under 1900-talet

The development of Swedish linguistics during the 20th century reflects international development. The century started with focus on language history described according to the theory of sound laws. It is reasonable to call the period around the turn of the century the Golden Age of Nordic philology; characterized by the work of Adolf Noreen; Axel Kock and Elof Hellquist who clarified the basic de