Platelet transfusion refractoriness is a serious clinical concern that complicates the management of thrombocytopenic patients. Previous studies have suggested a potential role for both complement and platelet activation based on in vitro analyses of platelet concentrates. In this study, the post-transfusion platelet response, as indicated by the corrected count increment at 1 and 24 h after proph

Previous research on variation in patient reported experience measures (PREMs) suggest that it is important to be cautious when using comparative information about patients’ experiences, collected via patient surveys, to assess provider performance. Not all factors associated with variation in PREMs are related to factors that providers themselves can control. This study explores if structural cha

PURPOSE: To derive Regional Diagnostic Reference Levels (RDRL) for paediatric conventional and CT examinations using weight-based DRL curves and compare the outcome with DRL derived using the weight groups.METHODS: Data from 1722 examinations performed at 29 hospitals in four countries were included. DRL was derived for four conventional x-ray (chest, abdomen, pelvis, hips/joints) and two types of

The efficiency of irrigation, as well as optimization of nutrients, affect spinach yield in all growth stages. In this study, the sensitivity of spinach (early and mature yields) to shallow saline groundwater and the effect of fertigation treatments on mature yield were experimentally investigated. The sprinkler irrigation experiments were conducted on 0.47 ha of silty clay soil at the University

The Covid-19 pandemic has spawned numerous dynamic modeling attempts aimed at estimation, prediction, and ultimately control. The predictive power of these attempts has varied, and there remains a lack of consensus regarding the mechanisms of virus spread and the effectiveness of various non-pharmaceutical interventions that have been enforced regionally as well as nationally. Setting out in data

To date, not that much. Improvements are possible, but some system-theoretically grounded re-design is necessary. We discuss the matter based on our experience, and as a consequence, we come to distilling some design clues and research directions.

Whether and how long-term energy and climate targets can be reached depend on a range of interlinked factors: technology, economy, environment, policy, and society at large. Integrated assessment models of climate change or energy-system models have limited representations of societal transformations, such as behavior of various actors, transformation dynamics in time, and heterogeneity across and

The regional variability in tundra and boreal carbon dioxide (CO2) fluxes can be high, complicating efforts to quantify sink-source patterns across the entire region. Statistical models are increasingly used to predict (i.e., upscale) CO2 fluxes across large spatial domains, but the reliability of different modeling techniques, each with different specifications and assumptions, has not been asses

The proposed European Union directive on minimum wages has met strong criticism in Scandinavia. But up to now the debate has lacked specific instances of what statutory minimum wages would mean for the Swedish labour market. A key feature of the Swedish industrial-relations system is that unions and employers regulate most aspects of the labour market through collective agreements. The Swedish-or

Double-chain amphiphilic compounds, including surfactants and lipids, have broad significance in applications like personal care and biology. A study on the phase structures and their transitions focusing on dioctadecyldimethylammonium chloride (DODAC), used inter alia in hair conditioners, is presented. The phase behaviour is dominated by two bilayer lamellar phases, Lβ and Lα, with “solid” and “

The Pleistocene-Holocene transition brought turbulent times to human societies confronted by rapid climatic fluctuations, shifts inbiogeographic zones and the flooding of continental shelves. While the disappearance of Doggerland’s inhabited landscapes underthe grey waters of the North Sea marks the culmination of these changes for European Archaeologists, our aim is this paper is todraw parallels

Knowledge of how to design digital systems that are ergonomically sound, high in usability, and optimized for the user, context, and task has existed for some time. Despite this, there are still too many examples of new digital health care systems that are poorly designed and that could negatively affect both the work environment of health care staff and patient safety. This could be because of a

Introduction: The aim of the study is to compare the effect of cervical length measured with transvaginal ultrasound in the second trimester on the risk of spontaneous preterm delivery (PTD) between different risk groups of asymptomatic women with a singleton pregnancy. Material and methods: This is a pre-planned exploratory analysis of the CERVIX study, a prospective blinded multicenter diagnosti

Non-invasive quantification of pressure-volume (PV) loops from brachial pressure and cardiovascular magnetic resonance is a validated method but its application has been limited to resting heart rates. The aim of this study was to improve the previous method and validate it against invasive left-ventricular pressure measurements in an experimental porcine model, and further apply it to 16 healthy