The biological functions of proteins depend on their physical interactions with other molecules, such as proteins and peptides. Therefore, modeling the protein-ligand interactions is important for understanding protein functions in different biological processes. We have focused on the cleavage specificities of HIV-1 protease, HCV NS3 protease and caspases on short oligopeptides or in native prote

Abstract is not available

Execution trace graph analysis of dataflow programs has been demonstrated to be an effective way for exploring and optimizing the design space of many core applications. In this work a novel transformation from the execution trace graph to an event driven linear system is proposed. It is also illustrated how the trace space of can be effectively reduced and well known system control techniques can

The effects of the phase lag on the suspended load in the ripple regime were investigated for oscillatory flows and combined steady and unsteady flows. The Camenen et al. (2005) suspended load formula was modified in order to take into account both current-related and wave-related sediment transport. A particular effort was made to better predict the phase-lag effects in the ripple regime. The mod

Wild bank voles (Clethrionomys glareolus) may develop diabetes in laboratory captivity. The aim of this study was to test whether bank voles develop type 1 diabetes in association with Ljungan virus. Two groups of bank voles were analyzed for diabetes, pancreas histology, autoantibodies to glutamic acid decarboxylase (GAD65), IA-2, and insulin by standardized radioligand-binding assays as well as

Kaposi's sarcoma-associated herpes virus (KSHV) encodes a complement inhibitor named KSHV complement control protein (KCP). We have previously shown that KCP inhibits the human complement system by disrupting the C3 convertase of complement. KCP can accelerate the decay of the classical C3 convertase and it can act as a cofactor for factor I (R), which then cleaves and inactivates C4b or C3b (in t

Chiral building blocks are needed in the chemical and pharmaceutical industries for the production of fine chemicals and pharmaceuticals. The utilisation of microorganisms and enzymes to perform stereoselective reductions of carbonyl compounds is an efficient and widely applied method for the generation of chiral molecules. The aim of this thesis was to develop and improve yeast-catalysed bioredu

Handledning är en praktik som under senare år kommit till användning inom en lång rad olika fält, allt ifrån utbildning inom skola, universitet och arbetsliv, professionell utveckling, organisations- och ledarutveckling till kultur- och fritidsverksamheter. Handledning - perspektiv och erfarenheter fokuserar på den bredd som finns inom ämnet, där varje fält hämtar idéer och arbetssätt från variera

Abstract is not available

I detta kapitel argumenterar jag för normkritiska och icke-förtryckande sätt att tänka inom undervisning och lärande. Efter en diskussion av argument som förs för och emot antidiskriminerings- och normkritisk arbete i skolan presenterar jag några av normkritiska pedagogikers teoretiska utgångspunkt. Det följs av en överblick över de regler som gäller för icke-diskriminering och inkludering i skoll