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Objectives - Because of the rarity of small bowel adenocarcinoma (SBA), little is known about the aetiology of this disease. This study aimed to identify occupational clustering of cases SBA as a systematic approach to new hypotheses on the aetiology of this disease. Methods - A European multicentre case-control study was conducted in 1995-7, inclusive. Incident cases aged 35-69 years with SBA (n=
Background: Crohn disease and biliary diseases have been associated with small-bowel adenocarcinoma (SBA). We examined how medical conditions affect the risk of SBA. Methods: A population-based European multicentre case-control study during the period 1995-97 including 95 histologically verified cases of SBA along with 3335 population controls; 70 cases (74%) and 2070 (62%) controls were interview
Doctoral education in the technical fields has several distinct features, such as, the research is often projectbased, interdisciplinary, dependent on external funding, and affiliated with an industry. In other words, the epitome of a “modern doctorate” (Fillery-Travis, 2017; Lee, 2018). While literature on doctoral supervision in general is abundant (see e.g. Gatfield, 2005; Gurr, 2001; Ives &
Only very recently has the concept of circular economy gained momentum in the public sphere, and inspired consequent research. Within the field of built environment, the debate is even more nascent. This study aims at developing the definition of circular economy specifically for the purposes of the real estate sector. A definition of circular economy in real estate, is derived from the results of
Narcolepsy type 1 (NT1) is a chronic sleep disorder caused by a specific loss of hypocretin-producing neurons. The incidence of NT1 increased in Sweden, Finland and Norway following Pandemrix®-vaccination, initiated to prevent the 2009 influenza pandemic. The pathogenesis of NT1 is poorly understood, and causal links to vaccination are yet to be clarified. The strong association with Human leukocy
We have developed an in-situ method using sonication (3 mm probe sonicator, 30 W, 20 kHz) and auto-reduction (control) to study the mechanism of the formation of manganese dioxide (MnO2) on a solid template (silk film), and its resulting enzymatic activity on tetramethylbenzidine (TMB) substrate. The fabrication of the silk film was first optimized for stability (no degradation) and optical transp
There is no apparent need for individuals to endure this kind of suffering in contemporary Western society with all its advantages. Nevertheless, endurance running is now a mainstream leisure pursuit. Why do hundreds of thousands of men, women and even children choose this torturous kind of leisure activity?In previous literature on consumption of extraordinary experiences, authors focus on the pu
As consumers in Western consumer culture have increasingly turned from high cultural to low cultural consumption categories to cultivate themselves, the meanings of the traditional and socio-cultural concepts used to represent different forms of consumer expertise have been blurred or altered. Drawing upon sociocultural literature on taste and distinction we attempt to provide theoretical clarity
he idea of person-centred health systems is widely advocated in political and policy declarations to better address health system challenges. A person-centred approach is advocated on political, ethical and instrumental grounds and believed to benefit service users, health professionals and the health system more broadly. However, there is continuing debate about the strategies that are available
Health care professionals frequently describe performance management and monitoring of efficiency and quality measures for external accountability as an administrative burden with limited benefits. Professionals argue that they are subject to too tight control that signals distrust, limits professional autonomy and ultimately decreases their motivation to perform. At worst, poorly incentivized ind
A central challenge in infection medicine is to determine the structure and function of host-pathogen protein-protein interactions to understand how these interactions facilitate bacterial adhesion, dissemination and survival. In this review, we focus on proteomics, electron cryo-microscopy and structural modeling to showcase instances where affinity-purification (AP) and cross-linking (XL) mass s
