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Once rooted in the Cold War experience of small and nonaligned European states, total defense has reemerged across Northern and Eastern Europe in response to Russia’s increasingly aggressive behavior. Finland, Norway, and Sweden are at the forefront of this revival, making total defense central to national security and societal resilience. This article examines why these three structurally similar
Pimavanserin was the first US Food and Drug Administration approved antipsychotic drug that does not block D2 dopamine receptors at therapeutic doses. Pimavanserin is a selective 5-HT2A receptor inverse agonist that reduces the frequency of hallucinations and delusions associated with Parkinson disease. Despite these attributes, pimavanserin prolongs the QT interval at therapeutic doses, limiting
Forskning visar att rika individer har ett större klimatavtryck än befolkningen i stort.Rikedom innebär också symbolisk makt, där de rikas liv och vanor kan påverkanormer för vad som uppfattas som ett gott och eftersträvansvärt liv. Men hur ser densvenska allmänheten på rikedom och rika individer i ljuset av klimatförändringarna?Har rika ett särskilt ansvar att sänka sina koldioxidutsläpp? Och fin
De ultrarikas höga utsläpp väcker frågor om miljardärernas klimatansvar. Ska de som släpper ut mest också minska sina utsläpp mest? Bör de ultrarikas inkomster begränsas eller styras om i ljuset av klimatkrisen? Vad tycker svenska folket? Det är frågor som välfärdsforskare i Lund och Göteborg just nu söker svar på.
Klimatavtryck från Sveriges och världens rikaste har ökat stadigt sedan 90-talet. Samtidigt har de med lägst inkomst minskat sina utsläpp. Nu undersöker forskare om begränsningar för superrika kan bidra till minskade utsläpp. Utopi eller frihetskränkande?
Background Treatment of severe hemophilia A (SHA) with FVIII concentrates is complicated by the development of neutralizing inhibitors in about 30% during the first 50 exposure days (EDs). Despite extensive research, inhibitor risk of different FVIII concentrates remains to be elucidated. Objectives This study aimed to analyze inhibitor development according to (classes of) individual FVIII concen
PURPOSE: We aimed to develop a predictive tool for anastomotic leakage (AL) following colon cancer surgery by combining a clinical early warning score (EWS) with the C-reactive protein (CRP) level.METHODS: The records of 1,855 patients who underwent colon cancer surgery at the Oxford University Hospitals NHS Foundation Trust between January 2013 and December 2018, with or without AL, were retrospe
BACKGROUND: Intestinal resection and a proximal stoma is the preferred surgical approach in patients with severe secondary peritonitis due to perforation of the small intestine. However, proximal stomas may result in significant nutritional problems and long-term parenteral nutrition. This study aimed to assess whether primary anastomosis or suturing of small intestine perforation is feasible and
The EU's Clean Energy Package introduced renewable and citizen energy communities (RECs/CECs) to strengthen citizen participation in electricity markets. Nordic countries, however, have long-standing traditions of community-based energy provision, including district heating cooperatives, small hydropower schemes, and wind cooperatives. This article examines how nationally embedded energy models in
Background: Clinical supervisors’ competence is central to student learning, particularly in the context of existing practical, organizational, and resource-related challenges in simulation-based education. This study explored clinical supervisors’ experience of acting as instructors during simulation-based learning in specialist nursing education in anesthesia and intensive care. Method: An explo
Given the reproducing kernel k of the Hilbert space Hk we study spaces Hk(b) whose reproducing kernel has the form k(1−bb⁎), where b is a row-contraction on Hk. In terms of reproducing kernels this is the most far-reaching generalization of the classical de Branges-Rovnyaks spaces, as well as their very recent generalization to several variables. This includes the so called sub-Bergman spaces [31]
Canopy decline is increasingly prevalent in high-elevation snow gum (Eucalyptus pauciflora) forests across the Australian Alps. This phenomenon, known as snow gum dieback, is associated with infestations by the wood-boring beetle, Phoracantha mastersi. The larvae of this beetle create feeding galleries in the tree trunk, leading to the exudation of kino, a tannin-rich resin produced as a defense r
The traditional approach to quantum parameter estimation focuses on the quantum state, deriving fundamental bounds on precision through the quantum Fisher information. In most experimental settings, however, performing arbitrary quantum measurements is highly unfeasible. In open quantum systems, an alternative approach to metrology involves the measurement of stochastic currents flowing from the s
We study the time complexity of computing the (min,+) matrix product of two n×n integer matrices in terms of n and the number of monotone subsequences the rows of the first matrix and the columns of the second matrix can be decomposed into. In particular, we show that if each row of the first matrix can be decomposed into at most m1 monotone subsequences and each column of the second matrix can b
Background: Cystic fibrosis related diabetes (CFRD) is the most common comorbidity of cystic fibrosis (CF) still, its pathogenesis is poorly understood. Recent studies have suggested that although pancreatic insufficiency is an important explanation for CFRD development, inherent pancreatic islet cell dysfunction may play a role. This study aimed to systematically compile current data regarding th
This paper considers the beta exponential distribution as a distribution function of inefficacy score in a stochastic frontier model. The beta exponential distribution is a three-parameter distribution, and it is more flexible than commonly used probability density functions in a stochastic frontier model (SFM). This new model, a “Normal-Beta Exponential SFM”, nests another five SFMs. This paper p
Approximately 1.9 million Colombians lacked access to clean and reliable energy in 2020 due to residing in rural non-interconnected zones (NIZ). This lack of reliable electricity is compounded by their geographical isolation which makes them unable to access the National Interconnected System of energy (SIN). Renewable energy microgrids serve as a potential decentralised solution to provide clean
