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The elusory kingdoms of the mind : Glosses on José Luis Caivano's paper

Peirce's best idea, and the one least implemented by himself and his followers, is that of an ethics of terminology. Using this ethics as a tool, we suggest that many Peircean terms are in fact misleading, or, as he said himself at the end of his life, "injurious."From the point of view of cognitive semiotics, there is no reason to abide by Peirce's definition of semiosis, but, taking up the two q

Wild Enchantments in the Anthropocene : Exploring the Wild in Narratives, Practices and Place in Dark Green Spirituality

This thesis is ta study of the intersection between dark green spirituality and the green movement in relation to climate change and ecological crisis, and it explores how some ecologically concerned people try to orientate themselves in facing the challenges and especially the role of spirituality in this context. The study is set in the period 2009–2015, and it is based in fieldwork conducted in

GHSR DNA hypermethylation is a common epigenetic alteration of high diagnostic value in a broad spectrum of cancers

Identification of a single molecular trait that is determinant of common malignancies may serve as a powerful diagnostic supplement to cancer type-specific markers. Here, we report a DNA methylation mark that is characteristic of seven studied malignancies, namely cancers of lung, breast, prostate, pancreas, colorectum, glioblastoma and B cell chronic lymphocytic leukaemia (CLL) (n = 137). This ma

High concentration of immunoglobulin A is associated with temporal lobe epilepsy

Introduction: Dysfunction of immunoglobulins (Igs) has been detected in association with antiepileptic drugs (AEDs) and in newly diagnosed epilepsy patients. The aim of this study was to evaluate the effect of clinical features and the current or past use of AEDs on serum Ig concentrations in a well-examined group of patients with refractory epilepsy. Patients and methods: Using a nephelometric me

Diagnostic values of GHSR DNA methylation pattern in breast cancer

DNA methylation patterns have been recognised as cancer-specific markers with high potential for clinical applications. We aimed at identifying methylation variations that differentiate between breast cancers and other breast tissue entities to establish a signature for diagnosis. Candidate genomic loci were analysed in 117 fresh-frozen breast specimens, which included cancer, benign and normal br

Lead-time in the european randomised study of screening for prostate cancer

Background: Lead-time is defined as the time by which screening advances the diagnosis compared with absence of screening. A sufficiently long lead-time needs to be achieved so that cancer can be detected while still curable. A very short lead-time may indicate poor sensitivity of the screening test, while a very long lead-time suggests overdiagnosis. Material and methods: In the first screening r

Optimal, Low-Complexity Beamforming for Discrete Phase Reconfigurable Intelligent Surfaces

Reflective reconfigurable intelligent surface (RIS) technology is regarded as an innovative, cost- and power-effective solution that aims at influencing the wireless channel through controlled scattering. The technology can be realized by using metamaterials and/or resonant elements that scatter electromagnetic waves with a configurable phase shift. Most of the previous work on beamforming techniq

Identification and Functional Characterization of a Novel Susceptibility Locus for Small Vessel Vasculitis with MPO-ANCA

OBJECTIVE: To identify and characterize genetic loci associated with the risk of developing anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitides (AAV).METHODS: Genetic association analyses were performed after Illumina sequencing of 1,853 genes and subsequent replication with genotyping of selected SNPs in a total cohort of 1110 Scandinavian cases with granulomatosis with polyangiit

Genetic variants at the RTP4/MASP1 locus are associated with fatigue in Scandinavian patients with primary Sjögren's syndrome

OBJECTIVES: Fatigue is common and severe in primary Sjögren's syndrome (pSS). The aim of this study was to identify genetic determinants of fatigue in pSS through a genome-wide association study.METHODS: Patients with pSS from Norway, Sweden, UK and USA with fatigue and genotype data available were included. After genotype imputation and quality control, 682 patients and 4 966 157 genetic markers

Seeing the green cucumber: Reflections on variation theory and teaching plant identification

Ett viktigt mål för samhället, särskilt för utbildningssystemen, är att vi människor blirbättre på att få syn på växter och på deras betydelse i ekosystemen. Vi behöver över-vinna vad som benämns ‘växtblindhet’. I denna artikel föreslår vi att variationsteoriär en bra utgångspunkt i utbildning och utvärdering av växtidentifiering inom högreutbildning. Vi redovisar exempel från svensk universitetsu

The Natural History of Musical Rhythm : Functional and Mechanistic Theories on the Evolution of Human Rhythm Cognition and the Relevance of Rhythmic Animal Behaviors

Recently, interest has been growing in investigating rhythm cognition and behavior in nonhuman animals as a way of tracking the evolutionary origins of human musicality—that is, the ability to perceive, enjoy, and produce music. During the past 2 decades, an explosion of theoretical proposals have aimed at explaining why and how humans have evolved into musical beings, and the empirical comparativ

The evolution of primate short-term memory

Short-term memory is implicated in a range of cognitive abilities and is critical for understanding primate cognitive evolution. To investigate the effects of phylogeny, ecology and sociality on short-term memory ability, we tested 421 non-human primates across 41 species in a pre-registered, experimental delayed-response task. Our results confirm previous findings that longer delays decrease memo