Gitelmans syndrome (GS) is an inherited recessive disorder caused by homozygous or compound heterozygous loss of function mutations of the NaCl cotransporter (NCCT) gene encoding the kidney-expressed NCCT, the pharmacological target of thiazide diuretics. An observational study estimated the prevalence of GS to 19/1 000 000, in Sweden, suggesting that similar to 1% of the population carries one mu

Operative treatment for distal radius fractures continues to evolve, but small-fragment fixation has some advantages compared with previous methods. We assessed two groups of patients. Group 1 was an initial series of patients treated with small-fragment fixation at a large institution in the United States, and Group 2 was a review of patients treated in Lund, Sweden. The first group was evaluated

The purpose of the present study is to assess QT-interval measurements from the EASI 12-lead electrocardiogram (ECG) as compared with the standard 12-lead ECG. The QT interval was automatically determined in simultaneously recorded standard and EASI 12-lead ECGs, using a validated wavelet-based delineator. The agreement between the 2 sets of measurements was quantified both on a lead-by-lead basis

We present the results from a thorough investigation of the bond strength between the photo-polymer SU-8 and Au. The data were obtained by pull-test experiments, below the glass transition temperature of the polymer. The different aspects that we investigated were: (i) the effect of using different adhesion promoters between the SU-8 and Au; (ii) the influence of the processing sequence, keeping e

Rogen moraine is widely distributed in the core areas of the former Scandinavian and Laurentide ice sheets. It is generally agreed upon that these gently arched, ice-How transverse ridges call be used in reconstructions of paleo-ice-flow patterns and that they indicate a melted-bed or poly-thermal basal ice regime. However, the processes of ridge generation have been contentious. This study propos

BACKGROUND: The house dust mite (HDM) Dermatophagoides pteronyssinus is an important source of allergens, which can cause allergic conditions. The cysteine protease activity of Der p 1 may enhance the potency of this major mite allergen through cleavage of CD23 and CD25 from the surface of immune cells, IgE independent mast cell activation, increases in epithelial cell permeability and inactivatio

Drinking stories are immensely popular among contemporary Danish youth. The stories are shared with much enthusiasm in school, at parties, over the telephone and via the Internet. But why are the young so compelled by these seemingly vulgar stories? Applying the theories of, most importantly, Bakhtin (1968), Ricoeur (1991), and Jackson (2002), this paper examines a sample of drinking stories that

Objectives: Peripartum cardiomyopathy (PPCM) is a rare disease carrying a risk of death and chronic heart failure.It is unknown if women with PPCM have a family history of heart failure. We investigated the prevalence of heart failure and hypertension in first-degree relatives to women with PPCM. Methods: A cohort of 61 women with PPCM was identified through the nationwide Danish registers from 20

Background: Vacations at international nightlife resorts represent an important but also risky element in the lives of youth in many countries. There is an urgent need for evaluating the role played by bars and nightclubs in producing and reducing risks; this task is important, especially at upcoming nightlife resorts with limited experience in managing young partygoers from other countries. Metho

Little is known about predictors of hangover symptoms. The subjective experience of the night out may influence the experience of hangover symptoms. We conducted a survey of 325 young men and women at a vacation resort during the daytime, administering subjects the Acute Hangover Scale (AHS) and asking questions about drinking and behaviors the night before. Half of the subjects reported feeling h

Background. People travelling abroad tend to increase their use of alcohol and other drugs. In the present study we describe organized party activities in connection with young tourists' drinking, and the differences between young people travelling with and without organized party activities. Methods. We conducted ethnographic observations and a cross-sectional survey in Sunny Beach, Bulgaria. Res

Aims: The aim of this study was to compare the patterns of substance use in young Danes while holidaying in the Bulgarian holiday resort of Sunny Beach (SB) to their patterns of substance use in Denmark. Methods: Data were collected from visitors to SB in 2007 (n = 1011). Information on alcohol and drug use was surveyed using a short questionnaire. Findings: Most individuals surveyed were regular

Sex and drinking go hand-in-hand in Western societies. Men also tend to report more sexual disinhibition under the influence of alcohol and drugs than women. At a vacation resort, we conducted a survey of young men and women regarding self-reported alcohol-related sexual disinhibition (ARSD), and we administered the Drinking-Induced Disinhibition Scale (DIDS). We made several comparisons of behavi

A study related to the separations of uranium traces in a concentrated Pu solution and plutonium traces in a concentrated U solution was performed (with Pu/U or U/Pu = 102–105). Its objective was to determine the U–Pu separation performances for a low U and Pu concentration range, namely: Pu solutions of 2.5 mg L−1 to 2.5 g L−1 containing traces of U (25 µg L−1), U solutions of 10 µg L−1 to 10 mg

Background: Understanding current patterns of functional decline will inform patient care and has health service and resource implications. Aim: This prospective consecutive cohort study aims to map the shape of functional decline trajectories at the end of life by diagnosis. Design: Changes in functional status were measured using the Australia-modified Karnofsky Performance Status Scale. Segment

The overarching objective of the studies in this thesis is to solve issues associated with the current district heating development in order to improve the efficiency, and thus the environmental performance, of district heating systems. More specifically, the aim is to solve issues related to prosumers and bottlenecks in district heating networks. Prosumers are consumers who also produce district The overarching objective of the studies in this thesis is to solve issues associated with the current district heating development in order to improve the efficiency, and thus the environmental performance, of district heating systems. More specifically, the aim is to solve issues related to prosumers and bottlenecks in district heating networks. Prosumers are consumers who also produce district