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The outcome of allo-HSCT for 92 patients with myelofibrosis in the Nordic countries

Between 1982 and 2009 a total of 92 patients with myelofibrosis (MF) in chronic phase underwent allo-SCT in nine Nordic transplant centers. Myeloablative conditioning (MAC) was given to 40 patients, and reduced intensity conditioning (RIC) was used in 52 patients. The mean age in the two groups at transplantation was 46 +/- 12 and 55 +/- 8 years, respectively (P

Characterizing motor and non-motor aspects of early-morning off periods in Parkinson's disease: An international multicenter study.

The characteristic off periods that develop over time in subjects with Parkinson's disease (PD) on chronic levodopa therapy are usually considered to be motor complications but more recently the important contribution of non-motor off and non-motor fluctuations has also been acknowledged. Early-morning off (EMO) periods in PD patients are known to be a cause of significant disability, in addition

Strain Profiling of a Ferritic-Martensitic Stainless Steel Sheet - Comparing Synchrotron with Conventional X-Ray Diffraction

To improve the fatigue resistance of stainless steel sheet, it is a common practice to induce compressive residual stress in the surface through shot-peening or tumbling. Stress depth profiles obtained by tumbling of thin stainless steel tensile rods were analysed using laboratory and synchrotron X-Ray Diffraction (XRD). Both the non-destructive synchrotron and the laboratory XRD etch-depth profil

Acute onset of ovarian dysfunction in young females after start of cancer treatment.

BACKGROUND: Female childhood cancer survivors are at risk of ovarian failure and premature ovarian insufficiency. We hereby present an interim analysis of a prospective observational study of ovarian function during cancer treatment of young females in relation to clinical factors. PROCEDURE: Thirty-four consecutive female cancer patients aged 0-18 year were included after informed consent. Ser

Sepsis-induced leukocyte adhesion in the pulmonary microvasculature in vivo is mediated by CD11a andCD11b.

Leukocyte accumulation is a rate-limiting step in inflammatory lung injury. The aim of this study was to define the role of CD11a/CD18 and CD11b/CD18 in sepsis-induced leukocyte rolling and adhesion in lung arterioles, capillaries and venules in male C57BL/6 mice using intravital fluorescence microscopy. Cecal ligation and puncture (CLP) markedly increased leukocyte rolling in arterioles and venul

Validation of the Distress Thermometer in a Swedish population of oncology patients; accuracy of changes during six months

Purpose: To validate the Swedish version of the Distress Thermometer (DT) against the Hospital Anxiety and Depression Scale (HADS) for screening of distress and to explore how well DT measures changes of distress during six months in a population of heterogeneous oncology patients. Methods: The DT was translated into Swedish according to the forward- and back-translation procedure. HADS total scor

Nomenclature of members of Hieracium sect. Alpestria, Foliosa and Prenanthoidea (Asteraceae) reported from Sweden

Names of taxa referred to Hieracium sect. Alpestria (including the ‘Semidovrensia group’), Foliosa and Prenanthoidea and reported from Sweden have been compiled from the literature and herbaria and all uses have been indexed. Based on this synopsis, the nomenclatural validity and legitimacy of the names are analysed. In total, the use of 75, 62 and 27 names is documented for the three sections, re

Carbon dioxide degassing in fresh and saline water. II: Degassing performance of an air-lift

A study was undertaken to measure the efficiency with which carbon dioxide was stripped from freshwater (0 parts per thousand) and saline water (35 parts per thousand NaCl) passing through an air-lift at 15 degrees C. The air-lift was constructed of 50 mm (OD) PVC pipe submerged 95 cm in a tank, had an adjustable air injection rate, and could be adjusted to three lifting heights: 11,16 and 25 cm.

Ferromagnetism and the electronic band structure in (Ga,Mn)(Bi,As) epitaxial layers

Impact of Bi incorporation into (Ga,Mn)As layers on their electronic-and band-structures as well as their magnetic and structural properties has been studied. Homogenous (Ga,Mn)(Bi,As) layers of high structural perfection have been grown by the low-temperature molecular-beam epitaxy technique. Post-growth annealing treatment of the layers results in an improvement of their structural and magnetic

Abnormal cerebellar development and ataxia in CARP VIII morphant zebrafish

Congenital ataxia and mental retardation are mainly caused by variations in the genes that affect brain development. Recent reports have shown that mutations in the CA8 gene are associated with mental retardation and ataxia in humans and ataxia in mice. The gene product, carbonic anhydrase-related protein VIII (CARP VIII), is predominantly present in cerebellar Purkinje cells, where it interacts w

On the probability of non-shared multipath clusters in cellular networks

In Space Division Multiple Access (SDMA) systems, users are separated based on their positions. The base-station (BS) signals typically reach the users through multipath clusters. The goal of this work is to find the probability that a randomly selected user will receive the signal from the BS via at least one nonshared (by any other user) multipath cluster. This probability, referred to as PSucce

Smart, smarter, smartest: foraging information states and coexistence

Animals possess different abilities to gain and use information about the foraging patches they exploit. When ignorant of the qualities of encountered patches, a smart forager Should leave all patches after the same amount of fixed search time. A smarter forager can be Bayesian by using information Oil Cumulative harvest and time spent searching a patch to better inform its patch-departure decisio

A behavioral perspective on the biophysics of the light-dependent magnetic compass: a link between directional and spatial perception?

In terrestrial organisms, sensitivity to the Earth's magnetic field is mediated by at least two different magnetoreception mechanisms, one involving biogenic ferromagnetic crystals (magnetite/maghemite) and the second involving a photo-induced biochemical reaction that forms long-lasting, spin-coordinated, radical pair intermediates. In some vertebrate groups (amphibians and birds), both mechanism

Methyl orange (CI acid orange 52) as a new organic semiconductor: Conduction mechanism and dielectrical relaxation

The structural, electrical and dielectrical properties of the methyl orange (MO) have been investigated by X-ray diffraction and thermal analysis methods. The electrical conduction and dielectrical relaxation mechanisms of the organic compound at various frequencies and temperatures were analyzed by impedance spectroscopy. The direct current (DC) electrical conductivity confirmed that methyl orang

Globalization, Democracy, and Child Health in Developing Countries

Good health is crucial for human and economic development. In particular poor health in childhood seems to be of utmost concern since it causes irreversible damage and has implications later in life. Recent research suggests globalization is a strong force affecting adult and child health outcomes. Yet, there is much unexplained variation with respect to the globalization effect on child health, i

Electron Spectroscopic Studies of Homogenous (GaMn) As Layers

By incorporating magnetism into semiconductors, it may possibly be viable to enhance the functionality of materials. An exceptionally important material in this context is GaAs, which can be doped with Mn atoms. (GaMn)As has fascinated research community as a promising candidate for spintronic application. It is quite appealing due to both its compatibility with existing III-V technology and great

A data mining approach to dinoflagellate clustering according to sterol composition: correlations with evolutionary history

Abstract in UndeterminedThis study examined the sterol compositions of 102 dinoflagellates using clustering and cluster validation techniques, as a means of determining the relatedness of the organisms. In addition, dinoflagellate sterol-based relationships were compared statistically to 18S rDNA-based phylogenetic relationships using the Mantel test. Our results indicated that the examined dinofl

The Impact of Captive Innovation Offshoring on the Effectiveness of Organizational Adaptation

We analyze the effects of captive offshoring of innovation activities on the firms' ability to adapt their organizational structures. Basing our arguments on the complexity theory, we use three consecutive waves of the German part of the Community Innovation Survey to test our hypotheses. We find an inverted u-shape of innovation offshoring on the effectiveness of organizational adaptability, impl