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While many mutations thought to result in protein S (PS) deficiency are known. there have been few attempts to relate genotype expression with plasma phenotype. We have investigated the nature and consequence of PS gene (PROS 1) mutations in 17 PS-deficient families who presented with mixed type I and type III phenotypes. Seven different mutations were found in nine families: delG-34 (STOP codon a
Popular Abstract in Swedish ?Överbrygga det kommunikativa gapet mellan personer med en demenssjukdom och deras vårdare. Ett omvårdnadsperspektiv? En problematik i omvårdnaden av personer med långt framskriden demenssjukdom är hur vårdare skall tolka och förstå den demensdrabbade så att omvårdnaden kan anpassas till dennes behov. Forskning tyder på att vissa reaktioner, bland annat aggressiva handThe aim was to explore possible areas and sources that could inform the care for people with dementia. These were the people with dementia themselves, nurses reflective discussions about caring, nurse-patient interaction together with information from close family members, and the previous personality and sense of coherence of people with dementia in relation to behaviour during the disease as rel
Scenarios of changes in biodiversity for the year 2100 can now be developed based on scenarios of changes in atmospheric carbon dioxide, climate, vegetation, and Land use and the known sensitivity of biodiversity to these changes. This study identified a ranking of the importance of drivers of change, a ranking of the biomes with respect to expected changes, and the major sources of uncertainties.
Alkaline sphingomyelinase (alk-SMase) is a new member of the NPP (nucleotide pyrophophatase/phosphodiesterase) family that hydrolyses SM (sphingomyelin) to generate ceramide ill the intestinal tract. The enzyme may protect the intestinal mucosa front inflammation and tumorigenesis. PAF (platelet-activating factor) is a pro-inflammatory phospholipid involved in pathogenesis of inflammatory bowel di
Develops a framework for manufacturing flexibility which illustrates how to obtain consistency from manufacturing strategy to the resource characteristics in the production system. Provides guidance on how to analyse and develop manufacturing flexibility in a corporate decision-making context. Uses the well-known input-transformation-output (ITO) model as a starting point for building the frame-wo
The aim was to compare urinary symptoms and their influence on daily life among elderly (75+) women and men in a sample that previously had reported difficulties controlling urine (urine incontinence (UI)) and/or other urinary symptoms (OU). A further aim was to find underlying structures of urinary symptoms and to identify symptoms that had an impact on seeking medical help and need of help in da
The spectroscopic properties of a molecule is strongly dependent on interactions with the surrounding environment. We have used time dependent density functional theory (TDDFT) and a multilevel perturbation model to study the transition energies, polarizability, and dipole moments of a bacteriochlorophyll in an electric field. The perturbation Hamiltonian was constructed as to give an electric fie
Thirty-five strains of Pasteurella multocida from humans and animals were tested for susceptibility to five cephalosporins by a broth dilution method. Cefcanel showed high activity against all isolates (MIC and MBC, less than or equal to 0.64 micrograms/ml). The corresponding figure for cefaclor and cefuroxime was 2.56 micrograms/ml. Cefadroxil and cephalexin were the least active compounds tested
Popular Abstract in Swedish POPULÄRVETENSKAPLIG SAMMANFATTNING För varje person som har problem med alkohol berör's i genomsnitt minst ytterligare en person. Under de senaste två decennierna har medvetenheten och kunskapen om de anhöriga's situation och hur de känslomässigt kan påverka's av ett långvarigt alkoholproblem ökat. Den stres's alkoholproblemet skapar påverkar den anhörige's samspel mRandomized studies of various support programs for spouses and children of alcoholics are few in the international literature. This thesis comprises two randomized controlled studies of intervention programs for two family groups: spouses living with an alcoholics partner (paper I and II) and university students who have grown up with at least one parents with alcohol problems (paper III and IV).
PURPOSE: This study assessed whether there is a dilating diathesis in peripheral arteries of patients with abdominal aortic aneurysms (AAAs). METHODS: The anteroposterior diameters of the common femoral artery (CFA) and popliteal artery (PA) were measured in 183 consecutive patients with an AAA (158 men, 25 women; age range, 57-78 years) before elective surgery on the AAA and compared with that of
This paper describes a method for online supervision of control loops that automatically detects oscillations in the loops. The paper describes the method, its implementation in a Honeywell TDC3000 system, and experiences obtained from its use in the mill AssiDomän Frövi.
The quality of the waste sampling procedure and chemical analysis was evaluated in a research program on characterization of organic waste obtained after disc screening of source-separated organic household waste. The sampling procedures focused on a truckload of waste and involved several steps of subsampling including shredding, mixing, blending, high-speed-blending, drying and milling prior to
Goran Sonnevi's poetry represents a vast network of associations to other texts and other works of art. Consequently, this poetry often initiates a conversation on the present with partners from different times, Places and arts. "Burge, Oja; 1989" is an interesting example of such an intermedial conversation, set in the middle of a dramatic period of our time, the year 1989. The central theme is t
A combined solid-phase extraction (SPE)-supercritical fluid extraction (SFE) procedure was developed for the analysis of polychlorinated biphenyls (PCBs) in wastewater. The importance of cleaning and drying the filters and SPE-disks prior to eluting PCBs with SFE was studied, leading to improved recoveries for all congeners investigated. The average PCB recovery of the final procedure, at a concen
In the first years of the twentieth century, numerous attempts were made at powered flight. What is commonly labelled 'the pioneer era' (1900-1914) covers the unsteady beginnings of the motorized airplane as well as its large-scale introduction in warfare and for the transportation of goods and passengers. Initially regarded as a foolish toy for hazardous adventure, the airplane rapidly became a f
Aims and objectivesTo explore how nurses and managers perceive that evidence‐based sources are obtained to inform relevant nursing interventions.BackgroundImplementation of evidence‐based practice requires a systematic search and evaluation of research, clinical expertise and consideration of the patients’ preferences and values. Much has been written over the past decade about how this should be
