OBJECTIVE-We tested genetic associations with weight loss and weight regain in the Diabetes Prevention Program, a randomized controlled trial of weight-loss inducing interventions (lifestyle and metformin) versus placebo. RESEARCH DESIGN AND METHODS-Sixteen obesity-predisposing single nucleotide polymorphisms (SNPs) were tested for association with short-term (baseline to 6 months) and long-term (

Detraditionalization in late modernity has both affected traditional religion and the domain of clinical therapy. Sweden, which is said to be one of the most secularized societies in the world, instead has allowed the public domain to be colonized by new, spiritualized practices. Sold as therapy, the services of new spiritual leaders offer anti-stress techniques to prevent burn-out, or leaders are

Avhandlingens empiriska syfte är att undersöka vad som händer när globala marknadsorienterade modeller för granskning och kvalitet tas i bruk i lokala församlingar. Särskild uppmärksamhet ägnas församlingarnas diakonala arbete. Undersökningen baseras på fallstudier där ett urval av församlingar och granskningsmodeller är studieobjektet. Avhandlingen har även ett teoretiskt syfte: att i samspel medThe empirical aim of the thesis is to investigate what happens when global market-oriented models for auditing and quality assessment are taken up by local parishes. Particular attention is paid to the diaconal work of the parishes. The study is based on case studies where a number of parishes and auditing models provide the object of study. The thesis also has a theoretical aim: to test, in inter

Big Science accelerator complexes are no longer mere tools for nuclear and particle physics, but modern-day experimental resources for a wide range of natural sciences and often named instrumental to scientific and technological development for innovation and economic growth. Facilities compete on a global market to attract the best users and facilitate the best science, and advertise the achievem

We report on the network characterization of a series of hybrid nanocomposites consisting of integrated anisotropic nanoparticles (NPs) within a polyurea elastomeric matrix with low weight fractions ranging from 0.3 to 1.2 wt%. The grafting method employed to incorporate the silica-coated spindle-type hematite nanoparticles (SCH NPs), promotes the stability of the NPs in dispersion, and further en

Innovation management (IM) is a multidisciplinary field which has been growing for the past few decades. However, the management of innovation is often considered equivalent to technology management or the management of research and development. By focusing on a set of small-and medium-sized enterprises operating in a medium-high-tech industry, the paper intends to determine the characteristics of

We consider a moving-boundary problem associated with the fluid model for biofilm growth proposed by J. Dockery and I. Klapper, Finger formation in biofilm layers, SIAM J. Appl. Math. 62 (3) (2001) 853–869. Notions of classical, weak, and variational solutions for this problem are introduced. Classical solutions with radial symmetry are constructed, and estimates for their growth given. Using a we

Digital LLRF technology has been widely used in new generation particle accelerators. IF quadrature sampling is a common method for amplitude and phase detection. Many strategies, which obey the same rule of f(sample) = (M/N)f(IF) (M/N is a rational number), have been proposed to reduce the effects of spectrum aliasing. However, we found that M/N does not need to be a rational number according to

Abstract in Spanish Tanto el cine como el concepto de género en la teoría queer comparten dos aspectos fundamentales: ambos son performativos y son entendidos como construcciones sociales. La teoría queer hoy en día sigue provocando reacciones adversas en la forma de entender el sexo, el género y la sexualidad y el cine de Almodóvar sigue siendo actual con el paso de los años. Éstas son las causasCinema and gender in queer theory share two fundamental aspects: both are performative and understood as social constructions. Nowadays, queer theory still causes adverse reactions with respect to the understanding of sex, gender and sexuality and Almodóvar's films have remained relevant until today. These two reasons lead us to the idea of looking at the film High Heels (Pedro Almodóvar, 1991) fr

Blood coagulation has a Janus-faced role in infectious diseases. When systemically activated, it can cause serious complications associated with high morbidity and mortality. However, coagulation is also part of the innate immune system and its local activation has been found to play an important role in the early host response to infection. Though the latter aspect has been less investigated, phy

Technical solutions for a number of Swedish industrial installations for dewatering and drying of bark are compiled and discussed. Further, lab-scale experiments with a heated bark pressing process have been performed to investigate to what extent parameters such as temperature and pressure will influence the dewatering process. Pressing with a heated press at 150 °C was shown to increase the dewa

Ionic microgels are intriguing soft and deformable colloids with an effective pair potential that crosses over from Yukawa-like at large distances to a much softer repulsive interaction at short distances. Here we report the effect of adding an anisotropic dipolar contribution to colloids with such "ultra-soft" interactions. We use an alternating electric field to induce a tunable dipolar contribu

A linearly polarized photon beam has been produced at MAX-lab using the coherent bremsstrahlung of electrons with an energy of 192.6 MeV in a 0.1 mm thick diamond crystal. The intensity and shape of the coherent maxima and their dependence on the crystal orientation are similar to the features observed at higher electron energies (similar to 1 GeV) and are well described by coherent bremsstrahlung

Popular Abstract in Swedish Mikroorganismer (bakterier, virus och protozoer) finns överallt I vår omgivning. Vi människor har tio gånger fler bakterier på och i oss än vi har mänskliga celler. De flesta bakterier orsakar sällan eller aldrig sjukdom, men det finns de som ofta orsakar sjukdom och dessa kallas patogener. För att skydda oss från patogener har vi ett komplicerat och välutvecklat immunfSeminal plasma is semen without the spermatozoa. Human seminal plasma is a complex mixture of secretions from the sex accessory glands, mainly the seminal vesicles and the prostate. Seminal plasma has high protein content and it also contains ions, sugars and low molecular weight components. Immediately after ejaculation the semenogelins and fibronectin aggregate and a coagulum forms trapping the

Popular Abstract in English The dissertation is divided into two parts. The first part deals with the development of a questionnaire diagnostic instrument for atopic dermatitis (AD). The second part concerns following a cohort and assessing the natural history of AD, in which the effect of specified risk factors is analysed. In Värmland, Sweden, a questionnaire that diagnoses AD in infants and preAbstract In childhood atopic dermatitis (AD) is the most frequent inflammatory condition. Validated eczema questionnaires have been available for schoolchildren only, but the incidence of atopic dermatitis is highest during infancy. Evidence is needed on the further development of asthma, and rhinitis in these infants with AD and on remission of AD in children. We aimed to validate a parental ques

Popular Abstract in Swedish Enterohemorragisk Escherichia coli (EHEC) EHEC är mycket virulent för människor, det räcker med så få som 50-100 bakterier för att man ska bli infekterad och utveckla symtom. Varje år rapporteras ca 300-500 fall av EHEC smitta i Sverige. Den stam som oftast isoleras från patienter är E. coli O157:H7. Reservoarer för EHEC är idisslare och framförallt kor. Kor är nämligHemolytic uremic syndrome (HUS) is characterized by non-immune hemolytic anemia, thrombocytopenia and acute kidney failure. The most common form of HUS is associated with gastrointestinal Shiga toxin-producing enterohemorrhagic Escherichia coli (EHEC) infection. EHEC are non-invasive strains with Shiga toxin as the unique virulence factor. The aim of this study was to describe host-pathogen intera