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Photoelectrocatalytic Oxidation of NADH at a Graphite Electrode Modified with a New Polymeric Phenothiazine

A new approach for photoelectrocatalytic oxidation of NADH is described, based on a graphite electrode (G) modified with a new phenothiazine derivative, polyphenothiazine formaldehyde (PPF). Electrochemical measurements reveal that G/PPF presents a quasireversible voltammetric response, corresponding to a 2e(-)/2H(+) transfer and that G/PPF modified electrodes show electrocatalytic activity for NA

Global Human Rights Awareness, Education and Democratization

The 1990s was the era of human rights awareness, democratic transitions, and growing involvement of international organizations and the nongovernmental sector in human rights education (HRE). The UN Decade for HRE from 1995-2004 was not only born out of the initiatives and pressures of nongovernmental organizations (NGOs) but it also actively triggered many new private initiatives and commitments

RNA and DNA interactions with zwitterionic and charged lipid membranes - A DSC and QCM-D study.

The aim of the present study is to establish under which conditions tRNA associate with phospholipid bilayers, and to explore how this interaction influence the lipid bilayer. For this purpose we have studied association of tRNA or DNA of different size and degree of base pairing with a set of model membrane systems with varying charge density, composed of zwitterionic phosphatidylcholines (PC) in

Gestational age at birth and risk of allergic rhinitis in young adulthood

Background: Previous studies of the association between gestational age or birth weight and allergic rhinitis in later life have had various limitations, including the inability to estimate risk among subjects born extremely preterm or to examine specific contributions of gestational age and fetal growth. Objective: We sought to determine whether gestational age at birth independent of fetal growt

OH*-chemiluminescence during autoignition of hydrogen with air in a pressurised turbulent flow reactor

Autoignition of hydrogen in air was studied in a turbulent flow reactor using OH*-chemiluminescence. High-speed imaging was used to visualise the formation of auto-ignition kernels in the flow, and to analyse the conditions under which temporary stabilisation of the flame kernels occurred. The experiments were carried out at temperatures of 800-850 K, pressures of 0.8-1.2 MPa and an equivalence ra

Two-Step Approach for the Prediction of Future Type 2 Diabetes Risk

OBJECTIVE-To develop a model for the prediction of type 2 diabetes mellitus (T2DM) risk on the basis of a multivariate logistic model and 1-h plasma glucose concentration (1-h PG). RESEARCH DESIGN AND METHODS-The model was developed in a cohort of 1,562 non-diabetic subjects from the San Antonio Heart Study (SAHS) and validated in 2,395 nondiabetic subjects in the Botnia Study. A risk score on the

Multi-Decadal Changes in Tundra Environments and Ecosystems: Synthesis of the International Polar Year-Back to the Future Project (IPY-BTF)

Understanding the responses of tundra systems to global change has global implications. Most tundra regions lack sustained environmental monitoring and one of the only ways to document multi-decadal change is to resample historic research sites. The International Polar Year (IPY) provided a unique opportunity for such research through the Back to the Future (BTF) project (IPY project #512). This a

Buffer layer free large area bi-layer graphene on SiC(0001)

The influence of hydrogen exposures on monolayer graphene grown on the silicon terminated SiC(0 0 0 1) surface is investigated using photoelectron spectroscopy (PES), low-energy electron microscopy (LEEM) and micro low-energy electron diffraction (mu-LEED). Exposures to ionized hydrogen are shown to have a pronounced effect on the carbon buffer (interface) layer. Exposures to atomic hydrogen are s

Pancreatic Cancer - Early Detection, Prognostic Factors, and Treatment

Popular Abstract in Swedish Pankreascancer, cancer i bukspottkörteln, är den fjärde vanligaste orsaken till död i cancer och årligen insjuknar cirka 1000 patienter i Sverige. Överlevnaden är kort med en 5-årsöverlevnad på endast 6 procent. Pankreascancer orsakar, förutom lidande, också betydande kostnader för såväl den medicinska vården, som förluster för samhället, exempelvis i form av förtida döBackground: Pancreatic cancer is the fourth leading cause of cancer-related death. Only about 6% of patients are alive 5 years after diagnosis. One reason for this low survival rate is that most patients are diagnosed at a late stage, when the tumor has spread to surrounding tissues or distant organs. Less than 20% of cases are diagnosed at an early stage that allows them to undergo potentially cu

Software News and Update MOLCAS 7: The Next Generation

Some of the new unique features of the MOLCAS quantum chemistry package version 7 are presented inthis report. In particular, the Cholesky decomposition method applied to some quantum chemical methods is described. This approach is used both in the context of a straight forward approximation of the two-electron integrals and in the generation of so-called auxiliary basis sets. The article describe

Continuous-Time Gray-Box Identification of Mechanical Systems Using Subspace-Based Identification Methods

We consider the problem of gray-box identification of dynamic models for mechanical systems. In particular, the problem is approached by means of continuous-time system identification using subspace-based methods based on discrete-time input-output identification data. A method is developed, with the property that the structure of the model resulting from fundamental physical first principles is o

Metastatic Breast Cancer: Biomolecular Characterization and Targeted Therapy

Popular Abstract in English Every year globally, an estimated 1.7 million women are diagnosed with breast cancer, while over half a million are killed by this disease. The principal cause of death is metastasis, which is the spreading of the cancer cells from the breast to other vital organs like the brain, liver or lungs, resulting in organ failure and subsequently death. Even though the past decMetastasis is a complex process that remains a major challenge in the clinical management of cancer, because most cancer-related deaths are attributed to disseminated disease rather than the primary tumor. Despite the significant advances in the prediction of prognosis, and therapeutic management of primary breast cancers, coupled with the substantial improvement in our understanding of the molecu

Childhood cancer survivor cohorts in Europe

With the advent of multimodality therapy, the overall five-year survival rate from childhood cancer has improved considerably now exceeding 80% in developed European countries. This growing cohort of survivors, with many years of life ahead of them, has raised the necessity for knowledge concerning the risks of adverse long-term sequelae of the life-saving treatments in order to provide optimal sc

Quantitative detection of myocardial ischaemia by stress echocardiography; a comparison with SPECT

Aims: Real-time perfusion (RTP) adenosine stress echocardiography (ASE) can be used to visually evaluate myocardial ischaemia. The RTP power modulation technique angio-mode (AM), provides images for off-line perfusion quantification using Qontrast (R) software, generating values of peak signal intensity (A), myocardial blood flow velocity (beta) and myocardial blood flow (Ax beta). By comparing re

Children in Old Bodies : Age and Ageing in the History of Institutional Psychiatry

The aim of this paper is to examine what meanings “age” was given when Swedish psychiatric institutions were defining, categorising and caring for their patients from 1850 to 1970. The paper focuses on institutional psychiatry’s perspectives on individuals of advanced age and on the way that these individuals were understood in terms directly or indirectly associated with age. The majority of aged

Towards an efficient atomic frequency comb quantum memory

We present an efficient photon-echo experiment based on atomic frequency combs [Phys. Rev. A 79 (2009) 052329]. Echoes containing an energy of up to 35% of that of the input pulse are observed in a Pr3+ -doped Y2SiO5 crystal. This material allows for the precise spectral holeburning needed to make a sharp and highly absorbing comb structure. We compare our results with a simple theoretical model w

Bimembrane diffusion probe for continuous recording of dissolved and entrapped bubble gas concentrations in peat

Peatlands are significant sources of the important greenhouse gas CH4 and generally known as sinks for atmospheric CO2 through peat accumulation. Accurate measurements of the subsurface concentrations of these gases are of pivotal importance for experimental studies improving our understanding of the dynamics and controls on the exchanges of these gases between peat soils and the atmosphere. In th