The adsorption of histatin 5 to hydrophilic silica surfaces is governed by electrostatic attractive forces between the positive protein and the negative surface. Hence pH and ionic strength control the adsorbed amount, which can be described by coarse-grained Monte Carlo simulations accounting for electrostatic forces and charge regulation of the protein.

This work describes and characterizes an algorithm for the nonambiguous reduction of multiexponentially decaying luminescence signals to scalar values of corresponding calibration temperatures. Previous evaluation schemes in phosphor thermometry make use of an intermediate step, where data reduction is achieved by fitting a model equation to phosphorescence decays in order to translate one or more

In their own view, public transportation companies make a very hospitable offer to commuters: if you are ready to travel with us, we will take you for a reasonable price nearly anywhere, every day and almost at any time of the day, under good conditions of comfort and safety. Please, step onboard. But commuters resist being reduced to the thankful guests of their commuting service providers. Commu

Costs related to pollen competition have rarely been considered, but are expected in the case of sexual conflict where male and female sexual functions have opposing evolutionary interests. In Collinsia heterophylla, delayed stigma receptivity is beneficial as it enhances pollen competition. A sexual conflict over timing of stigma receptivity has been proposed in this species as early pollination,

Objective: To assess associations and genotype x treatment interactions for melanocortin 4 receptor (MC4R) locus variants and obesity-related traits. Design and Methods: Diabetes prevention program (DPP) participants (N = 3,819, of whom 3,356 were genotyped for baseline and 3,234 for longitudinal analyses) were randomized into intensive lifestyle modification (diet, exercise, weight loss), metform

OBJECTIVE: The concordance index (c-index) is the standard way of evaluating the performance of prognostic models in the presence of censored data. Constructing prognostic models using artificial neural networks (ANNs) is commonly done by training on error functions which are modified versions of the c-index. Our objective was to demonstrate the capability of training directly on the c-index and t

Since the formulation of the mobilities paradigm, research has shown that movement is increasingly at the heart of our social identities. This paper argues that mobility, and indeed, hypermobility, constitutes to a growing extent who we are, whilst societal perspectives on mobility increasingly dictate how we need to move in time and space in order to accrue network capital. In this critical revie

Invasive species and bottom-water hypoxia both constitute major global threats to the diversity and integrity of marine ecosystems. These stressors may interact with unexpected consequences, as invasive species that require an initial environmental disturbance to become established can subsequently become important drivers of ecological change. There is recent evidence that improved bottom-water o

There is accumulating evidence that gestational diabetes (GDM) is a growing problem. The lack of internationally standardized diagnostic procedures prevents consistent diagnosis and the burden of GDM must be determined in country-specific studies. In southern Sweden, GDM is defined as a 2-hour capillary plasma glucose concentration of ≥10.0 mmol/L during a universal 75 g oral glucose tolerance tes

Increased serum concentrations of the beta subunit of human chorionic gonadotropin (hCG beta) are associated with adverse prognosis in several cancers. The aim of the present study was to analyse the association between serum hCG beta recurrence, and survival, in patients with colorectal cancer. The concentrations of hCG beta were determined in serum collected preoperatively from 324 patients with

One subproject within the global Chromosome 19 Consortium is to define chromosome 19 gene and protein expression in glioma-derived cancer stem cells (GSCs). Chromosome 19 is notoriously linked to glioma by 1p/19q codeletions, and clinical tests are established to detect that specific aberration. GSCs are tumor-initiating cells and are hypothesized to provide a repository of cells in tumors that ca

Formaldehyde is the American Contact Dermatitis Society Contact Allergen of the Year for 2015. The exposure is widespread, and contact allergy might be difficult to suspect in the individual dermatitis patient. The relevance of contact allergy to formaldehyde might also be difficult to evaluate. Recently, however, several studies have been performed aimed at enhancing the patch test technique and

We present cathodoluminescence data of nanowires (NWs) grown using size-selected gold particles as seeds. The NWs have a GaAs core with a diameter of 50 nm and a length of several mu m. The NWs in this study were generally covered with a shell of AlGaAs. With increasing growth temperature, the emission intensity increases significantly. From a variety of growth conditions, we conclude that the exp

Objective: The acceptable noise level (ANL) is used to quantify the amount of background noise that subjects can accept while listening to speech, and is suggested for prediction of individual hearing-aid use. The aim of this study was to assess the repeatability of the ANL measured in normal-hearing subjects using running Danish and non-semantic speech materials as stimuli and modulated speech-sp

To investigate whether early coronary angiography (CAG) after out-of-hospital cardiac arrest of a presumed cardiac cause is associated with improved outcomes in patients without acute ST elevation.

Biomarkers are needed to improve current diagnosis and surveillance strategies for patients with Barrett's oesophagus (BO) and oesophageal adenocarcinoma (OAC). Macrophage inhibitory cytokine 1/growth differentiation factor 15 (MIC-1/GDF15) tissue and plasma levels have been shown to predict disease progression in other cancer types and was therefore evaluated in BO/OAC.

Background and Purpose: Natriuretic peptides predict poor outcomes in cardiovascular disease. However, the knowledge of their relationship to stroke is limited and prospective studies from the general population are few. The purpose of this study was to explore the relationship between N-terminal pro-brain natriuretic peptide (NT-proBNP) and midregional pro-atrial natriuretic peptide (MR-proANP) p

A set of concotto samples, a type of fired mixture of various raw materials, coming from firing place of the perifiuvial protohistoric site of Longola (Campania region, southern Italy) was characterized by means of a multi-analytical approach, i.e. polarized light optical microscopy (OM), X-ray powder diffraction (XRD), scanning electron microscopy and energy dispersive spectrometry (SEM-EDS), X-r