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Migration of the creative class: evidence from Sweden

A central element in contemporary regional development strategies is the ability for regions to attract and retain talented people. The underlying argument is that by attracting talented people, regions are better geared to meet the demand of competences of the knowledge economy and become more competitive. This article focuses on the migration of the creative class in Sweden. Three questions, cen

Binding of human C4BP to the hypervariable region of M protein: a molecular mechanism of phagocytosis resistance in Streptococcus pyogenes

The amino-terminal hypervariable region (HVR) of streptococcal M protein is required for the ability of this virulence factor to confer phagocytosis resistance. The function of the HVR has remained unknown, but the finding that many HVRs with extremely divergent sequences bind the human complement regulator C4b-binding protein (C4BP) has suggested that this ligand may play a role in phagocytosis r

Effects of weight reduction on plasma lipoproteins and adipose tissue metabolism in obese subjects

The relationship between obesity and alterations in adipose tissue metabolism and lipid transport was studied in fourteen obese subjects before and after a weight reduction of 4-22 kg. Blood glucose and plasma insulin patterns after peroral glucose intake improved significantly, and plasma glucagon levels decreased markedly after treatment. Plasma triglyceride and total cholesterol levels were not

Glycaemic index

The glycaemic index (GI) concept is based on the difference in blood glucose response after ingestion of the same amount of carbohydrates from different foods, and possible implications of these differences for health, performance and well-being. GI is defined as the incremental blood glucose area (0-2 h) following ingestion of 50 g of available carbohydrates in the test product as a percentage of

Facile Pretreatment of Bacilius circulans beta-Galactosidase Increases the Yield of Galactosyl Oligosaccharides in Milk and Lactose Reaction Systems

The commercially available preparation of beta-galactosidase from Bacillus circulans, known as Biolacta FN5, has been extensively used in the production of prebiotic galactooligosaccharides (GOS). This study focuses on characterizing the production of GOS in two reaction systems: 10% lactose (w/v) in buffer and skim milk. Analysis of the temperature dependence of the GOS yield along with the relat

The clinical value of serum S-100 protein measurements in minor head injury: a Scandinavian multicentre study

PURPOSE: This study of patients with minor head injury was designed to investigate the relation of S-100 protein measurements to computed tomograpy (CT) findings and patients outcomes. Increased serum levels of this protein were hypothetized to predict intracranial pathology and increased frequency of post-concussion symptoms. METHODS: One hundred and eighty-two patients were studied with Glasgow

Spermatophore size and multiple mating: Effects on reproductive success and post-mating behaviour in the Indian meal moth

Ensuring fatherhood is an important issue in polygamous species. In many lepidopteran species, the male inserts a large package (spermatophore) consisting of sperm, accessory gland fluids and nutrients into the female's bursa copulatrix during copulation. In most species it has been shown that a large mate donation causes females either to stop calling, or to prolong the time until re-mating, here

Design of decoupled PI controller for two-by-two systems

The design of PI controllers for systems with interacting loops is discussed. It is advantageous to deal with the interaction at the loop level, because supervisory control seldom has sufficient bandwidth. A new scheme based on modified scalar PI design and static decoupling is developed, in which the frequency characteristic of the coupling between the lower-level loops is taken into account. Thi

Having the wrong friends? Peer effects in adolescent substance use

Swedish cross-sectional survey data on young individuals aged 12-18-year-old was used to analyse school-class based peer effects in binge drinking, smoking and illicit-drug use. Significant and positive peer effects were found for all three activities. By introducing school/grade fixed effects, the estimated peer effects were identified by variation in peer behaviour across school-classes within s

Decoupling of Far Field Boundary From Magnetically Permeable Regions by Coupling the Reduced Scalar Potential to the Total Scalar Potential

It is known for a fact that the far-field boundary causes expensive computer calculations, when applying the finite element method to Maxwells equations. The reason is of course that a magnetic potential of some kind must be forced to zero at an appropriate distance from the disturbance, in electromagnetics the conductor. Various methods have been examined to reduce the cost of these calculations.

Laminin isoforms differentially regulate adhesion, spreading, proliferation, and ERK activation of beta1 integrin-null cells.

The presence of many laminin receptors of the β1 integrin family on most cells makes it difficult to define the biological functions of other major laminin receptors such as integrin α6β4 and dystroglycan. We therefore tested the binding of a β1 integrin-null cell line GD25 to four different laminin variants. The cells were shown to produce dystroglycan, which based on affinity chromatography boun

Image artifacts due to a time-varying contrast medium concentration in 3D contrast-enhanced MRA

The purpose of this work was to study image effects due to time-varying contrast medium concentration in contrast-enhanced three dimensional (3D) magnetic resonance angiography (MRA) images. Two different simulation models (1D and 3D) and two different contrast medium variation schemes were used. Phantom measurements were also performed. Experiments were performed for several different bolus timin

Mitochondrial permeability transition in acute neurodegeneration.

Acute neurodegeneration in man is encountered during and following stroke, transient cardiac arrest, brain trauma, insulin-induced hypoglycemia and status epilepticus. All these severe clinical conditions are characterized by neuronal calcium overload, aberrant cell signaling, generation of free radicals and elevation of cellular free fatty acids, conditions that favor activation of the mitochondr

Observation of states beyond band termination in Er-156,Er-157,Er-158 and strongly deformed structures in Hf-173,Hf-174,Hf-175

High-spin terminating bands in heavy nuclei were first identified in nuclei around Er-158(90). While examples of terminating states have been identified in a number of erbium isotopes, almost nothing is known about the states lying beyond band termination. In the present work, the high-spin structure of Er-156,Er-157,Er-158 has been studied using the Gammasphere spectrometer. The subject of triaxi

Integrated analysis of conditions accounting for intersite distribution of grassland plants

The objectives are to relate species distributions among 110 non-fertilized grassland ('dry meadow') sites in southeastern Sweden to soil chemical, physical, exposure and management variables using correlation, stepwise regression and factor (PCA) analysis based on quantitative data. It was suggested that soil acidity variables (pH, base saturation, exchangeable Ca, Al, Mn,and Fe), P, K, Mg, and N

Industrial biotechnology for the production of bio-based chemicals - a cradle-to-grave perspective

Shifting the resource base for chemical production from fossil feedstocks to renewable raw materials provides exciting possibilities for the use of industrial biotechnology-based process tools. This review gives an indication of the current developments in the transition to bio-based production, with a focus on the production of chemicals, and points out some of the challenges that exist in the la