Sulfur-containing compounds are used as rescue agents to protect normal tissue from the toxic side effects of cis-[PtCl2(NH3)(2)] (cisplatin) without affecting its anti-tumour activity. Reactions of the model complexes [Pt(dien)Cl](+) (1) and [Pt(dien)(GSMe)](2+) (2) (GSMe = S-methylglutathione) with the rescue agents glutathione (GSH), thiourea, thiosulfate, and diethyldithiocarbamate (DDTC) have

With the characterization of the total genomes of Arabidopsis thaliana and Oryza sativa, several putative plasma membrane components have been identified. However, a lack of knowledge at the protein level, especially for hydrophobic proteins, have hampered analyses of physiological changes. To address whether protein complexes may be present in the native membrane, we subjected plasma membranes is

We argue that ine + e –-annihilation (including -decay) deuteron production should be given by the overlap of the deuteron wave function with the wave function of apn-pair. The production rate depends sensitively upon the size of the production region. Taking into account the strong correlation between protons and neutrons, experimental results for -decay are consistent with the size expected in t

The complex salt (ionic surfactant + polymeric counterion) cetyltrimethylammonium polyacrylate (CTAPA) has been synthesized, and its aqueous mixtures with cetyltrimethylammonium bromide (CTABr) have been studied. These mixtures differ from conventional oppositely charged polymer/surfactant mixtures in that the conventional counterion of the polyion (usually sodium, for the polyacrylate) is absent,

The internal structure of composite gels made of responsive microgel particles inserted into a bulk hydrogel (N-isopropylacrylamide microgel particles in a cross-linked dimethylacrylamide matrix) has been investigated from the diffusion behavior of poly(ethylene glycol) (PEG) probes through the network, in the absence of specific interactions between the diffusing molecules and the system. The eff

1. The objective of the present study was to examine the role of the endothelial selectins (i.e. P- and E-selectin) in leukocyte-endothelium interactions in colonic venules by use of intravital microscopy. 2. Balb/c mice were exposed to dextran sodium sulphate (DSS) in the drinking water for 5 days or treated intraperitoneally (i.p.) with tumour necrosis factor-alpha (TNF-alpha) for 3 h. 3. In DSS

Purpose: We evaluated the effects of beta-adrenoceptor agonists on detrusor hyperreflexia in cerebral infarcted rats. Materials and Methods: To produce cerebral infarction in Sprague-Dawley rats the left middle cerebral artery was occluded by introducing a monofilament nylon thread into the artery. In sham operated rats the same artery was exposed but not occluded. After these operations cystometr

The pH and salt dependent self-association of hen egg-white lysozyme (HEWL) has been studied extensively, mainly by scattering techniques, but it has proven difficult to distinguish oligomerization from long-range interactions. Because HEWL is the principal model system in studies of protein crystallization, it is important to establish its oligomerization behavior unambiguously. Here, we address

Alport syndrome (AS) is a type IV collagen hereditary disease characterized by progressive hematuric nephritis, hearing loss, and ocular changes. Mutations in the COL4A5 collagen gene are responsible for the more common X-linked dominant form of the disease characterized by much less severe disease in girls and women. A "European Community Alport Syndrome Concerted Action" (ECASCA) group was estab

Popular Abstract in Swedish Avhandlingen består av en introduktion samt fyra artiklar. Avhandlingen behandlar externa kostnader till följd av väg- och järnvägstransporter. Den första artikeln skattar sambandet mellan antalet vägtrafikolyckor och antalet fordon på vägen. Fordonsflödet behandlas dels som bestående av homogena fordon och dels som bestående av bilar och lastbilar. Resultatet tyder på This thesis consists of an introductory chapter and four research papers, summarized as follows. The overall purpose is to study various external effects of the transport system; effects that are not considered (or not fully considered) today. The first paper estimates the relationship between accident frequency and homogeneous and inhomogeneous traffic flows, which is useful for calculating the

Popular Abstract in Swedish Undersökningarna som presenteras i avhandlingen behandlar mätning av produkter från och händelser i förbränningsprocessen genom att använda laserbaserade mätmetoder. Ett antal olika körfall, som HCCI och partially premixed combustion (PPC), har undersökts. I de första mätningarna som presenteras jämförs uppmätta flödesfält i cylindern med resultat från CFD och blåsriggThe work presented in this thesis deals with measuring in-cylinder combustion species and events using different laser-based diagnostic methods. A variety of engine operating modes, like HCCI and partially premixed diesel combustion, have been investigated. In the very first measurements, in-cylinder flow-fields were compared to CFD and steady-state blow rig results. After that, the ignition and

The aim of this work was to study the dependence of image quality in digital chest and pelvis radiography on tube voltage, and to explore correlations between clinical and physical measures of image quality. The effect on image quality of tube voltage in these two examinations was assessed using two methods. The first method relies on radiologists' observations of images of an anthropomorphic phan

Cultural and moral dimensions of waste.