BACKGROUND: Although lifestyle factors have been studied in relation to individual non-communicable diseases (NCDs), their association with development of a subsequent NCD, defined as multimorbidity, has been scarcely investigated. The aim of this study was to investigate associations between five lifestyle factors and incident multimorbidity of cancer and cardiometabolic diseases. METHODS: In thi

Many application areas for embedded systems, such as DSP, media coding, and image processing, are based on stream processing. Stream programs in these areas are often naturally described as graphs, where nodes are computational kernels that send data over the edges. This structure also exhibits large amounts of concurrency, because the kernels can execute independently as long as there are data to

Denna rapport kartlägger vilken form av finanspolitiskt ramverk som bäst kan undvika de mekanis- mer som idag hotar den finansiella stabiliteten i euroområdet. Diskussionen bygger på en gransk- ning av de fiskala relationerna mellan den federala och delstatliga nivån i fyra federala stater: Argentina, Brasilien, Kanada och USA. En jämförelse mellan de fyra staterna visar på en tydlig skillnad. De

We implemented a functional neuronal network that was able to learn and discriminate haptic features from biomimetic tactile sensor inputs using a two-layer spiking neuron model and homeostatic synaptic learning mechanism. The first order neuron model was used to emulate biological tactile afferents and the second order neuron model was used to emulate biological cuneate neurons. We have evaluated

Introduction: The objective was to create a clinically useful prediction model for vaginal birth in trial of labor after one cesarean section, appropriate for a third trimester consultation. Material and methods: Women with one cesarean section and at least one following delivery (N = 38 686) in the Swedish Medical Birth Register, 1998-2013, were studied. The women were randomly divided into one d

Human embryonic stem cells (hESCs) and induced pluripotent stem cells (iPSCs) can be differentiated into many different cell types of the central nervous system. One challenge when using pluripotent stem cells is to develop robust and efficient differentiation protocols that result in homogenous cultures of the desired cell type. Here, we have utilized the SMAD-inhibitors SB431542 and Noggin in a

Cryptosystems based on Learning with Errors or related problems are central topics in recent cryptographic research. One main witness to this is the NIST Post-Quantum Cryptography Standardization effort. Many submitted proposals rely on problems related to Learning with Errors. Such schemes often include the possibility of decryption errors with some very small probability. Some of them have a som

Purification of proteins for the biophysical analysis of protein interactions occurring in human cells can benefit from methods that facilitate the capture of small amounts of natively processed protein obtained using transient mammalian expression systems. We have used a novel calcium-dependent fragment complementation-based affinity method to effectively purify full length glycogen synthase kina

Background: The incidence and short- and long-term outcomes of coronary artery perforation (CAP) are not well described. Methods and Results: We analyzed the characteristics and the short- and long-term outcomes of CAP among 243,149 patients undergoing percutaneous coronary interventions (PCI) from 2005 until 2017 in the national Swedish registry. We identified 1,008 cases of CAP with an incidence

Mobile head-worn eye trackers allow researchers to record eye-movement data as participants freely move around and interact with their surroundings. However, participant behavior may cause the eye tracker to slip on the participant’s head, potentially strongly affecting data quality. To investigate how this eye-tracker slippage affects data quality, we designed experiments in which participants mi

Denna serie (ISBN 978-91-986003-0-8) innehåller den litauenjudiske statsmannen, folkrättsjuristen och sionistiske diplomaten Shimshon Rosenbaums (1859–1934) samlade verk på originalens språk med fullständiga översättningar till engelskan. I band 2 samlas hans artiklar och tal om folkrätt, sionism samt den judiska nationens självbestämmande, autonomi och statlighet.

Cellular proteins are subject to frequent methylation on lysine residues, introduced by specific methyltransferases, and each lysine residue can receive up to three methyl groups. Histone methylations, which are key determinants of chromatin state and transcriptional status, have been subject to particularly intense studies, but methylations on non-histone protein substrates are also abundant and

The aeolian deposits of Sweden have received modest attention, despite their usefulness as a palaeoenvironmental archive. Here we present sedimentological information and optically stimulated luminescence (OSL) ages from inland sand dunes in the lowlands of south-central Sweden. Three main lithofacies, each with two subfacies, were identified in the deposits: massive sand, laminated sand and cross

Identifying the environmental factors that shape intraspecific genetic and phenotypic diversity of species can provide insights into the processes that generate and maintain divergence in highly diverse biomes such as the savannas of the Neotropics. Here, we sampled Qualea grandiflora, the most widely distributed tree species in the Cerrado, a large Neotropical savanna. We analyzed genetic variati

In this paper, a unique event is studied: the opening of Bank of Canada in 1935, the central bank note issuance monopoly and its impact on the note issuing chartered banks. Between 1935-1950, Canadian chartered banks had to gradually withdraw their notes from circulation. In a difference-in-differences analysis, I show that chartered banks constrained by new issuance limits experienced higher vola