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Gender and the Outcome of Postcardiotomy Veno-arterial Extracorporeal Membrane Oxygenation

Objective: There is a paucity of sex-specific data on patients’ postcardiotomy venoarterial extracorporeal membrane oxygenation (VA-ECMO). The present study sought to assess this issue in a multicenter study. Design: Retrospective, propensity score–matched analysis of an international registry. Setting: Multicenter study, tertiary university hospitals. Participants: Data on adult patients undergoi

Tailoring plasmonic resonances in Cu-Ag metal islands films

The plasmonic response of Cu-Ag metal islands films is investigated. Films are obtained by subsequent electron beam deposition of Ag and Cu using different fabrication conditions: deposited mass thickness, substrate temperature and post-deposition annealing in vacuum. Optical properties of films are investigated by spectroscopic ellipsometry and correlated with the structural characterization resu

Decoding mechanical cues by molecular mechanotransduction

Cells are exposed to a variety of mechanical cues, including forces from their local environment and physical properties of the tissue. These mechanical cues regulate a vast number of cellular processes, relying on a repertoire of mechanosensors that transduce forces into biochemical pathways through mechanotransduction. Forces can act on different parts of the cell, carry information regarding ma

A framework for evaluating societal safety interventions

Societal safety concerns maintaining critical social functions to protect the life and health of citizens as well as to meet their basic needs in times of crisis. Societal safety interventions are implemented by a range of actors in society. However, systematic evaluations of the suitability and effectiveness of proactive societal safety interventions are rather scarce – especially for complex int

Breathlessness across generations : Results from the RHINESSA generation study

Background: Breathlessness is a major cause of suffering and disability globally. The symptom relates to multiple factors including asthma and lung function, which are influenced by hereditary factors. No study has evaluated potential inheritance of breathlessness itself across generations. Methods: We analysed the association between breathlessness in parents and their offspring in the Respirator

Large screen enabled tri-port MIMO handset antenna for low LTE bands

In recent years, the screen-to-body ratio of mobile handsets has been increasing. Today, the screen nearly fills up the entire front side. Conventionally, the screen is mainly seen as a metallic object that adversely affects antenna performance. In this paper, the large screen is used for the first time to facilitate an additional uncorrelated MIMO port in a tri-port design, for several LTE bands

Widespread Decoding of Tactile Input Patterns Among Thalamic Neurons

Whereas, there is data to support that cuneothalamic projections predominantly reach a topographically confined volume of the rat thalamus, the ventroposterior lateral (VPL) nucleus, recent findings show that cortical neurons that process tactile inputs are widely distributed across the neocortex. Since cortical neurons project back to the thalamus, the latter observation would suggest that thalam

Potential drug target identification in porphyromonas gingivalis using in-silico subtractive metabolic pathway analysis

Introduction: Porphyromonas Gingivalis (P. gingivalis) a primary periodontal disease pathogen. This bacterium affects sub-gingival tissue and leads to loss of teeth and alveolar bone destruction in the acute stage. In recent years, P. gingivalis is often connected with other diseases such as rheumatoid arthritis, diabetes, Alzheimer’s, and heart disease, though the aetiology is still unclear. Obje

A world of innumberable inactivities Martin Hägglund and the economy of non-existence

This essay challenges Martin Hägglund's interpretation of the hope of immortality as a longing for death and his identification of life with survival. It does so by interpreting the epitaph of the charwoman, which John Maynard Keynes refers to in "Economic Possibilities for our Grandchildren", as an eschatological speculation on what the dead are doing in the afterlife. The epitaph expresses a sab

Widely Different Correlation Patterns Between Pairs of Adjacent Thalamic Neurons In vivo

We have previously reported different spike firing correlation patterns among pairs of adjacent pyramidal neurons within the same layer of S1 cortex in vivo, which was argued to suggest that acquired synaptic weight modifications would tend to differentiate adjacent cortical neurons despite them having access to near-identical afferent inputs. Here we made simultaneous single-electrode loose patch

Critical realism, feminism, and gender : A reader

In assessing the current state of feminism and gender studies, whether on a theoretical or a practical level, it has become increasingly challenging to avoid the conclusion that these fields are in a state of disarray. Indeed, feminist and gender studies discussions are beset with persistent splits and disagreements. This reader suggests that returning to, and placing centre-stage, the role of phi

A case study of industry–academia communication in a joint software engineering research project

Empirical software engineering research relies on good communication with industrial partners. Conducting joint research both requires and contributes to bridging the communication gap between industry and academia (IA) in software engineering. This study aims to explore communication between the two parties in such a setting. To better understand what facilitates good IA communication and what pr

Human METTL18 is a histidine-specific methyltransferase that targets RPL3 and affects ribosome biogenesis and function

Protein methylation occurs primarily on lysine and arginine, but also on some other residues, such as histidine. METTL18 is the last uncharacterized member of a group of human methyltransferases (MTases) that mainly exert lysine methylation, and here we set out to elucidate its function. We found METTL18 to be a nuclear protein that contains a functional nuclear localization signal and accumulates

Why we keep separating the ‘inseparable’ : Dialecticising intersectionality

Disputes about how to understand intersectional relations often pivot around the tension between separateness and inseparability, where some scholars emphasise the need to separate between different intersectional categories while others claim they are inseparable. In this chapter the author takes issue with the either/or thinking that underpins an unnecessary and unproductive polarisation in the