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Photoelectron angular distributions for the two-photon ionization of helium by ultrashort extreme ultraviolet free-electron laser pulses

The two-photon ionization of helium atoms by ultrashort extreme-ultraviolet free-electron laser pulses, produced by the SPring-8 Compact SASE Source test accelerator, was investigated at photon energies of 20.3, 21.3, 23.0 and 24.3 eV. The angular distribution of photoelectrons generated by two-photon ionization is obtained using a velocity map imaging spectrometer. The phase-shift differences and

Adolescents' Experiences of sexual abuse - Prevalence, abuse characteristics, disclosure, health and ethical aspects

Popular Abstract in Swedish SVENSK SAMMANFATTNING Huvudsyftet med denna avhandling var att undersöka olika aspekter av självrapporterade sexuella övergrepp under barndom och ungdomstid i en befolkningsstudie med svenska gymnasieelever. Ett av målen var att undersöka livstidsprevalensen för olika typer av sexuella övergrepp och olika övergreppsvariabler samt relationen mellan sexuella övergrepp, köABSTRACT The purpose of this thesis was to investigate aspects of self-reported sexual abuse during childhood and adolescence in a population-based study of Swedish high school students. The aim of this thesis was first to investigate the lifetime prevalence of sexual abuse of varying severity and characteristics as well as the associations between sexual abuse, gender, socio-demographic character

Low toxicity regimens in renal transplantation: a country subset analysis of the Symphony study

P>Regional transplant practices may affect clinical outcomes within multinational studies. This study evaluated whether the overall results from the Symphony study can be generalized to the participating countries. De novo adult renal transplant recipients (n = 1645) were randomized to receive standard-dose cyclosporine, or daclizumab induction plus low-dose cyclosporine, low-dose tacrolimus, or l

Analysis of borehole geophysical data from the Mora area of the Siljan Ring impact structure, central Sweden

The Siljan impact structure is the largest known impact structure in Europe, the result of a Late Devonian meteorite impact (380.9 +/- 4.6 Ma). It is outlined mainly by a ring of lakes and Palaeozoic sedimentary rocks of Ordovician to Devonian age. The Palaeozoic successions are generally poorly exposed, but often well preserved with clear stratigraphy. At some locations they are strongly tectonis

Emerging pharmacotherapies for Parkinson's Disease: Experimental studies in the rat

Parkinson´s disease (PD) is a neurodegenerative disorder characterized by the typical motor symptoms, akinesia/bradykinesia, rigidity and resting tremor. These symptoms are caused by a deficiency of dopamine (DA) in the brain, which depends on degeneration of DA neurons in the substantia nigra. The most effective treatment for PD is the DA precursor, L-DOPA. Unfortunately, within a few years, L-DO

antibody microarray analysis of directly labelled proteomes

In recent years, the antibody microarray technology has made significant progress, going from proof-of-concept designs to established high-performing technology platforms capable of targeting non-fractionated complex proteomes. In these cross-disciplinary efforts, a particular focus has lately been placed on two key technological issues: the sample and data handling. To this end, robust protocols

Aberrant DNA methylation of cancer-associated genes in gastric cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC-EURGAST)

Epigenetic events have emerged as key mechanisms in the regulation of critical biological processes and in the development of a wide variety of human malignancies, including gastric cancer (GC), however precise gene targets of aberrant DNA methylation in GC remain largely unknown. Here, we have combined pyrosequencing-based quantitative analysis of DNA methylation in 98 GC cases and 64 controls ne

Can histology solve the riddle of non-functioning electrodes; factors influencing the biocompatibillity of brain machine interfaces.

Neural interfaces hold great promise to become invaluable clinical and diagnostic tools in the near future. However, the biocompatibility and the long-term stability of the implanted interfaces are far from optimized. There are several factors that need to be addressed and standardized when improving the long-term success of an implanted electrode. We have chosen to focus on three key factors when

A quarter of a century of job transitions in Germany

By examining trends in intra-organizational and inter-organizational job transition probabilities among professional and managerial employees in Germany, we test the applicability of mainstream career theory to a specific context and challenge its implied change assumption. Drawing on data from the German Socio-Economic Panel (GSOEP), we apply linear probability models to show the influence of tim

Measurement of D*(+/-) meson production and determination of F-2(c(c)over-bar) at low Q(2) in deep-inelastic scattering at HERA

Inclusive production of D* mesons in deep-inelastic ep scattering at HERA is studied in the range 5 < Q(2) < 100 GeV2 of the photon virtuality and 0.02 < y < 0.7 of the inelasticity of the scattering process. The observed phase space for the D* meson is (pT) (D*) > 1.25 GeV and |eta( D*)| < 1.8. The data sample corresponds to an integrated luminosity of 348 pb(-1) collected with the H1 detector. S

Novel lactic acid bacteria inhibiting Paenibacillus larvae in honey bee larvae

We evaluated the antagonistic effects of newly identified lactic acid bacteria (LAB) in the genera Lactobacillus and Bifidobacterium, originating from the honey stomach, on the honey bee pathogen, Paenibacillus larvae. We used inhibition assays on agar plates and honey bee larval bioassays to investigate the effects of honey bee LAB on P. larvae growth in vitro and on AFB infection in vivo. The in

Energy-driven asymmetric partitioning of a semiflexible polymer between interconnected cavities

The distribution of a semiflexible chain in the volume of two interconnected spherical cavities of equal size has been investigated by using Monte Carlo simulations. The chain possessed an extension exceeding that of the cavity, leading to large probabilities of translocated states despite the entropic penalty of passing the narrow passage. Furthermore, an asymmetric state with unequal subchain le

Two-Year Outcomes in Thoracic Transplant Recipients After Conversion to Everolimus With Reduced Calcineurin Inhibitor Within a Multicenter, Open-Label, Randomized Trial.

BACKGROUND.: Use of the mammalian target of rapamycin inhibitor everolimus with an accompanying reduction in calcineurin inhibitor (CNI) exposure has shown promise in preserving renal function in maintenance thoracic transplant patients, but robust, long-term data are required. METHODS.: In a prospective, open-label, multicenter study, thoracic transplant recipients more than or equal to 1 year po

LTD4 signalling via beta-catenin: a possible link between inflammation and cancer

The pro-inflammatory mediator LTD4 is an important component in the pathogenesis of inflammatory conditions as inflammatory bowel diseases. Patients suffering from inflammatory bowel diseases face an increased risk of intestinal cancer development. Therefore it is important to investigate the role of LTD4 signalling in cancer development and progression. In this thesis I show that there is an end

Gender differences in workers with identical repetitive industrial tasks: exposure and musculoskeletal disorders.

OBJECTIVES: For unknown reasons, females run a higher risk than males of work-related musculoskeletal disorders. The aim of this study was to evaluate whether male and female workers, with identical repetitive work tasks, differ concerning risk of disorders, physical or psychosocial exposures. METHODS: Employees in two industries were studied; one rubber manufacturing and one mechanical assembly p

Renewable energy costs, potentials, barriers: Conceptual issues

Renewable energy can become the major energy supply option in low-carbon energy economies. Disruptive transformations in all energy systems are necessary for tapping widely available renewable energy resources. Organizing the energy transition from non-sustainable to renewable energy is often described as the major challenge of the first half of the 21st century. Technological innovation, the econ

The initial care when a child is diagnosed with type 1 diabetes

When a child is diagnosed with diabetes, the symptoms may be in its most severe form with ketoacidosis, to mild symptoms of diabetes, detected incidentally. Moderate and severe symptoms of diabetes presentation require infusion therapy and thereby necessitate hospitalisation for the first few days. The initial management is largely a preparation for family members to help them gain the practical u

The Gaia-ESO Survey: Metallicity of the Chamaeleon I star-forming region

Context. Recent metallicity determinations in young open clusters and star-forming regions suggest that the latter may be characterized by a slightly lower metallicity than the Sun and older clusters in the solar vicinity. However, these results are based on small statistics and inhomogeneous analyses. The Gaia-ESO Survey is observing and homogeneously analyzing large samples of stars in several y