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Contractility of human leg lymphatics during exercise before and after indomethacin

Subcutaneous lymphatics in the lower leg were catheterized in the retrograde direction in 6 healthy male subjects. The catheter was connected to a pressure transducer, and pressure was measured during three stages of exercise including standing, tip-toeing, and running in place. Before the third stage, indomethacin (50mg) was given i.v. Rhythmic pressure waves were registered in each subject. Duri

Redetermination of the hyperfine structure of the 6p^(2)P_(3/2) level in Cs 133 by the zero field optical double resonance method

By combining recent level crossing data with the results from a modified atomic beam experiment by Buck, Rabi, and Senitzky in 1956, a Landégj factor deviating about 0.6% from the LS-value -1.3341 is obtained for the 6p2P3/2 level of Cs133. As this large deviation is difficult to explain, a remeasurement of the hyperfine structure of this level was performed by the zero field optical double resona

The charge capacity of the chemical bond

A bond capacitance is introduced via the LoProp formalism, and the calculated bond capacitances reflects the properties of the corresponding chemical bond remarkably well. It is clearly possible to characterize the properties of the chemical bond with the help of the calculated bond capacitances.

Det sociala spelet om Romano Platso

This thesis has been taking a starting point from a micro-level that focuses social structures, ethnic segregation and processes of development as phenomena from different levels of perspectives. The research focuses on housing-conditions in the urban room and take a starting-point in 1992 when an increased number of immigrant households, depending on social welfare, moved into Herrgården (Manor-H

Ageing as a result of the psychophysiological interaction during the life-span? A theoretical model

The variations in functional capacity, life quality and health increase as people grow older. Most likely, this is the result of a lifelong process in which both "wear-and-tear" and constructive development play a major role. Life experiences all the way from daily hazards to burdensome life events, to long-term exposure, to stress and strain might wear out the body. Life experiences of self-fulfi

Modelling the effect of function and disease activity on costs and quality of life in rheumatoid arthritis

Objective. When treatments with the potential to change the natural history of a disease are introduced, their longer-term effect on costs and quality of life (utility) has to be estimated using economic models. However, to remain useful tools, models must be updated when new information becomes available. Our earlier models in rheumatoid arthritis (RA) have been based on functional status, but it

Resistance to fluoroquinolones in Pseudomonas aeruginosa and Klebsiella pneumoniae

The fluoroquinolone sensitivity of Pseudomonas aeruginosa and Klebsiella pneumoniae was studied by determinations of Minimum Inhibitory Concentrations (MICs) of norfloxacin and ciprofloxacin in consecutive clinical isolates. In P. aeruginosa, resistance or reduced susceptibility (MIC > or = 8 mg/l for norfloxacin and > or = 2 mg/l for ciprofloxacin) was found in 17% (9/54) of the isolates. Reduced

Accurate dosimetry in I-131 radionuclide therapy using patient-specific, 3-dimensional methods for SPECT reconstruction and absorbed dose calculation

I-131 radionuclide therapy studies have not shown a strong relationship between tumor absorbed dose and response, possibly due to inaccuracies in activity quantification and dose estimation. The goal of this work was to establish the accuracy of I-131 activity quantification and absorbed dose estimation when patient-specific, 3-dimensional (3D) methods are used for SPECT reconstruction and for abs

Unga arbetslösas ansikten : Identitet och subjektivitet i det svenska och danska samhället

Popular AbstractStudier om undomars arbetsmotivation och inställning till arbete fokuserar ofta på skolundomar, vilket kan ge idealiserade bilder eftersom dessa ungdomar ännu inte försökt ta sig in på arbetsmarknaden. Verica Stojanovics avhandling fokuserar emellertid på ”äldre” (20-29 åriga) svenska och danska ungdomar som varit arbetslösa i några månader eller mer och hunnit känna av hur det är My aim is to show how unemployed youth, in Sweden and Denmark, during the years 1992-1996, were coping with their situation as unemployed, by focusing on their motivation for work, their conception of work, and their alternative action. Swedish youth have for a number of decades lived with a labour market policy which has had full employment as a goal and included active measures. Danish youth hav

Combining sequence-specific probes and DNA binding dyes in real-time PCR for specific nucleic acid quantification and melting curve analysis

Currently, in real-time PCR, one often has to choose between using a sequence-specific probe and a nonspecific double-stranded DNA (dsDNA) binding dye for the detection of amplified DNA products. The sequence-specific probe has tire advantage that it only detects the targeted product, while the nonspecific dye has the advantage that melting curve analysis can be performed after completed amplifcat

Mechanisms of inhibition of lipolysis by insulin, vanadate and peroxovanadate in rat adipocytes

Vanadate and peroxovanadate (pV), potent inhibitors of tyrosine phosphatases, mimic several of the metabolic actions of insulin. Here we compare the mechanisms for the anti-lipolytic action of insulin, vanadate and pV in rat adipocytes. Vanadate (5 mM) and pV (0.01 mM) inhibited lipolysis induced by 0.01-1 microM isoprenaline, vanadate being more and pV less efficient than insulin (1 nM). A loss o

Differential effect of hypothermia on the vascular tone and reactivity of the human coronary artery and graft vessels

Hypothermia may contribute to vascular spasm during bypass surgery. The effect of cooling on the reactivity of the human coronary artery (CA), saphenous vein (SV) and internal mammary artery (IMA) was studied in vitro. In CA and IMA cooling diminished the resting tension and the contraction to potassium, noradrenaline and 5-hydroxytryptamine. In contrast, in SV the contraction to noradrenaline and

Variable stability of chromosomes containing amplified alpha-satellite sequences in human mesenchymal tumours

Alpha-satellite sequences are found in the centromeric region of all human chromosomes and have been implicated in centromeric function. We describe the structure and behaviour of chromosomes containing amplified human alphoid DNA from chromosome 12, in an osteosarcoma cell line (OSA) and an atypical lipomatous tumour (ALT). In OSA, the amplified material was detected in one large marker chromosom