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Vegetation-Climate Feedbacks Enhance Spatial Heterogeneity of Pan-Amazonian Ecosystem States Under Climate Change

Amazonian ecosystems range from rainforest to open dryland vegetation, with a following decrease in biomass along the moisture gradient. Biomass can vary greatly at the ecological transition zone between grass dominated savannahs and the forest. It is not well understood if the transition zone could expand under climate change, and thereby reduce ecosystem stability and carbon storage in biomass.

Cerebrospinal fluid biomarker panel for synaptic dysfunction in Alzheimer's disease

Introduction: Synaptic dysfunction and degeneration is one of the earliest events in Alzheimer's disease (AD) and the best correlate of cognitive decline. Thus, identification and validation of biomarkers reflecting synaptic degeneration to be used as prognostic biomarkers are greatly needed.Method: Solid-phase extraction and parallel reaction monitoring mass spectrometry were used to quantify 17

Local Fisheries and Thriving Harbors: Is There a Value for the Tourism Sector?

Local commercial fishing is often claimed to attract tourists to coastal communities. We investigate the impact of local fishing on tourism demand, measured as overnight stays, in Sweden. Using municipal-level data for the period 1998–2015, we perform a quantitative analysis using ordinary least squares (OLS) as well as panel-data methods that take unobserved heterogeneity between municipalities i

Atomic-Scale Observation of Oxygen Vacancy-Induced Step Reconstruction in WO3

As the most common type of defects in WO3, surface oxygen deficiencies have been widely investigated in terms of their structure as well as physicochemical properties. In general, oxygen vacancy on the surface may lead to the reconstruction of the surface structure due to the need for surface energy minimization, especially for the area with high oxygen vacancy concentration. However, such a pheno

Swedish guidelines for device-aided therapies in Parkinson's disease —Economic evaluation and implementation

Objectives: The National Board of Health and Welfare in Sweden published the national guidelines for Parkinson's Disease 2016. The aim of this study was to summarize this evidence review and development of the guidelines, focusing on the economic evaluation of device-aided therapies (deep brain stimulation, pump-based infusion of levodopa-carbidopa intestinal gel or apomorphine) for Parkinson's di

Modelling and Simulation of the Fifth-Generation District Heating and Cooling

Fjärrvärme och fjärrkyla är ändamålsenliga system för distribution av värme och kyla i tätbebyggda områden. Dessa system är viktiga vid planeringen av framtida energieffektiva system på grund av deras höga potential för att integrera förnybara energikällor. Systemen spelar också en viktig roll i samhällets energiförsörjningssäkerhet, vilket gör dem till ett tvärvetenskapligt forskningsområde. Den District heating and cooling are efficient systems for distributing heat and cold in urban areas. They are a key solution for planning future urban energy-efficient systems due to their high potential for integrating renewable energy sources. The systems also play an important role in community resilience, which makes them a multidisciplinary research topic. The continuous development of these sys

Diagnostic center for primary care patients with nonspecific symptoms and suspected cancer : compliance to workflow and accuracy of tests and examinations

OBJECTIVE: To evaluate compliance to workflow and accuracy of tests in Sweden's first fast-track referral pathway for patients with nonspecific symptoms and suspected cancer (SCAN).DESIGN: Prospective cohort study with consecutive inclusion of patients referred to the diagnostic center (DC).SETTING: Patients with nonspecific symptoms were examined in primary care according to a protocol including

Windows: a study of residents’ perceptions and uses in Sweden

What are inhabitants’ perceptions and uses of windows in multi-dwelling buildings? This paper reports on a field study that explores daylight, the visual connection to the outside and the role of windows in the home during the day and night. Qualitative interviews were held with 20 participants living in multi-dwelling buildings. The thematic analysis identified two main components as characterist

Detection of Mycobacterium tuberculosis complex DNA in CD34-positive peripheral blood mononuclear cells of asymptomatic tuberculosis contacts : an observational study

Background: Haematopoietic stem cells expressing the CD34 surface marker have been posited as a niche for Mycobacterium tuberculosis complex bacilli during latent tuberculosis infection. Our aim was to determine whether M tuberculosis complex DNA is detectable in CD34-positive peripheral blood mononuclear cells (PBMCs) isolated from asymptomatic adults living in a setting with a high tuberculosis

Catch-up dynamics in early industry lifecycle stages - A typology and comparative case studies in four clean-tech industries

The literature on catch-up cycles has not yet systematically conceptualized how catch-up dynamics differ between the various industries that are emerging in the green techno-economic paradigm. We address this gap by connecting catch-up cycle theory with an industry typology from global innovation systems (GISs) literature, which distinguishes four generic industry types with footloose, spatially s

Finns det ett samband mellan yrkesfiske och turism?

Det finns en uttalad politisk vilja att stödja det lokala fisket i Sverige. Ett skäl till detta är att levande fiskehamnar kan locka turister till kustnära samhällen. I denna studie analyserar vi kopplingen mellanyrkesfiske och antalet gästnätter på hotell, vandrarhem och stugbyar.* Vi finner att antalet gästnätter är högre i kustkommuner med mer yrkesfiske.* Vi finner däremot inte stöd för att yr

The physical and mental impact of surviving sepsis – a qualitative study of experiences and perceptions among a Swedish sample

Background: Sepsis is a critical illness with high morbidity and mortality rates. Each year, sepsis affects about 48.9 million people all over the world. This study aims to illuminate how sepsis survivors experience sepsis and the impact of sepsis, as well as the health-related quality of life thereafter. Methods: An interview study with eight sepsis survivors was carried out in Sweden with an ind

Antibodies against apoB100 peptide 210 inhibit atherosclerosis in apoE-/- mice

Atherosclerotic plaques are characterized by an accumulation and subsequent oxidation of LDL, resulting in adaptive immune responses against formed or exposed neoepitopes of the LDL particle. Autoantibodies against native p210, the 3136–3155 amino acid sequence of the LDL protein apolipoprotein B-100 (apoB100) are common in humans and have been associated with less severe atherosclerosis and decre

Methotrexate reduces circulating Th17 cells and impairs plasmablast and memory B cell expansions following pneumococcal conjugate immunization in RA patients

Methotrexate (MTX) impairs antibody response after pneumococcal vaccination. We aimed to investigate differences in phenotypes of circulating B and T cells after pneumococcal conjugate vaccine (PCV) in rheumatoid arthritis (RA) patients on MTX (MTX group), RA without disease-modifying drugs (0DMARD), and controls (HC). MTX group (n = 11), 0DMARD (n = 12) and HC (n = 13) were studied. Blood samples

A fighting fetish : On transnational police and their warlike presentation of self

Transnational police readily use martial language in the stories they tell about their work. Their actual work, however, tells a different and less dramatic story. Why, then, do they insist on these warlike tales? Why is there a discrepancy between the self-representation of transnational policing and its reality? Using an ethnographic study, this article provides some answers. First, it includes

Joy of living through exercise - a qualitative study of clinically referred adolescents’ experiences of moderate to vigorous exercise as treatment for depression

Aim: Depression is common and rising in adolescents. Recent meta-analyses indicate a moderate effect of exercise on depression symptoms. Clinically referred adolescents and their experiences of an exercise intervention have rarely been studied. The aim of this study was to describe clinically referred adolescents’ experience of moderate to vigorous exercise as a treatment for depression. Methods: