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Objective - Disturbances in hippocampal neurogenesis may be involved in the pathophysiology of depression and it has been argued that an increase in the generation of new nerve cells in the hippocampus is involved in the mechanism of action of antidepressants. Materials and Methods - Adult Wistar rats were treated with fluoxetine (10 mg/kg) 1 h, daily for 5 (subchronic) or 28 days (chronic) before
This article discusses the concept of planetary boundaries that has been advanced by a group of leading experts around Johan Rockstrom. I place the concept of planetary boundaries in the larger framework of the emerging research paradigm of earth system governance, welcoming it as a crucial contribution that defines the overall goals of governance. Yet I also elaborate on the political conflicts t
This study examined how root growth and morphology were affected by variation in soil moisture at four Amazon rainforest sites with contrasting vegetation and soil types. Mean annual site root mass, length and surface area growth ranged between 3-7 t ha(-1), 2-4 km m(-2) and 8-12 m(2) m(-2) respectively. Mean site specific root length and surface area varied between 8-10 km kg(-1) stop and 24-34 m
Food with inputs from genetically modified organisms (GMOs) has met considerable skepticism among European Union (EU) consumers. The EU import ban on GM food has triggered a great deal of controversy and has been partly replaced by a mandatory labeling scheme. Although there is no measure in the General Agreement on Tariffs and Trade that directly addresses the use of product labeling, WTO and oth
The objective of this work was to examine the atazanavir-bilirubin relationship using a population-based approach and to assess the possible application of bilirubin as a readily available marker of atazanavir exposure. A model of atazanavir exposure and its concentration-dependent effect on bilirubin levels was developed based on 200 atazanavir and 361 bilirubin samples from 82 patients receiving
The breast cancer diagnosis covers a wide range of tumours with different geno- and phenotypic characteristics. The diversity among studies on life-style factors and their impact on breast cancer risk might be clarified by recognizing breast cancer as a heterogeneous disease. A major aim of this thesis was to investigate the association between several life-style factors and subsequent breast canc
Four systems for household food waste collection are compared in relation the environmental impact categories eutrophication potential, acidification potential, global warming potential as well as energy use. Also, a hotspot analysis is performed in order to suggest improvements in each of the compared collection systems. Separate collection of household food waste in paper bags (with and without
OBJECTIVE-Hemoglobin A(1c) (A1C) has emerged as a recommended diagnostic tool for identifying diabetes and subjects at risk for the disease. This recommendation is based on data in adults showing the relationship between A1C with future development of diabetes and microvascular complications. However, studies in the pediatric population are lacking. RESEARCH DESIGN AND METHODS-We studied a multiet
Chromosomal translocations of transcription factors generating fusion proteins with aberrant transcriptional activity are common in acute leukemia. In acute promyelocytic leukemia (APL), the promyelocytic leukemia-retinoic-acid receptor alpha (PML-RARA) fusion protein, which emerges as a consequence of the t(15;17) translocation, acts as a transcriptional repressor that blocks neutrophil different
Understanding tree recruitment is needed to forecast future forest distribution. Many studies have reported the relevant ecological factors that affect recruitment success in trees, but the potential for genetic-based differences in recruitment has often been neglected. In this study, we established a semi-natural reciprocal sowing experiment to test for local adaptation and microenvironment effec
The Cambrian 'Orsten' fauna comprises exceptionally preserved and phosphatised microscopic arthropods. The external morphology of these fossils is well known, but their internal soft-tissue anatomy has remained virtually unknown. Here, we report the first non-biomineralised tissues from a juvenile polymerid trilobite, represented by digestive structures, glands, and connective strands harboured in
There has been considerable interest in the directionality of resource specialisation during the diversification of lineages. We developed a quantitative method to investigate habitat specialisation in a radiation of New Zealand triplefin fishes, as habitat use appears to be an important axis of diversification in this marine group. The degree of specialisation in 15 species was calculated by comp
Atmospheric nuclear weapons testing in the late 1950s and early 1960s almost doubled the amount of C-14 in the atmosphere. The resulting C-14 "bomb-pulse" has been shown to provide useful age information in e.g. forensic and environmental sciences, biology and the geosciences. The technique is also currently being used for retrospective cell dating in man, in order to provide insight into the rate
Tungsten particles have been introduced into the National Spherical Torus Experiment (NSTX) in Princeton with the purpose to investigate the effects of tungsten injection on subsequent plasma discharges. An experimental setup for the study of tungsten particle transport is described where the particles are introduced into the tokamak using a modified particle dropper, otherwise used for lithium-po
Biological treatment in wastewater treatment plants (WWTPs) is a source of nitrogen oxides (N2O, NO and NO2) emitted to the atmosphere. Aerobic ammonia-oxidising bacteria (AOB) have been suggested to be the main source of these emissions. In a full-scale sludge liquor treatment plant at Sjolunda WWTP, it was shown that significant emissions of N2O, NO and NO2 do occur. The plant is operated with n
The dilution effect of N-2/CO2 on the laminar burning velocity of H-2-CO-O-2 mixtures was investigated. The dilution fraction of N-2 and CO2 in the unburned mixtures varied from 0% to 70% and 0%-50%, respectively, and H-2 content in H-2-CO fuels altered from 5% to 100%. All the studies were carried out at standard laboratory conditions (1 atm, 298 K) with equivalence ratio changing from 0.6 to 2.0
Popular Abstract in Swedish Idén om ett särskilt slag av algebraiska strukturer, kallade "vertexoperator-algebror", uppstod på 1980-talet. Dessa algebror används för att formulera fenomen inom fysikens strängteori. Närmare bestämt beskrivs partiklar inom denna teori som vibrerande linjer (eller slutna öglor) snarare än punkter, och algebrornas operatorer avser att visa hur två sådana strängar kan The main purpose of this thesis is the study of the structure and representation theory of simple vertex operator algebras (VOAs) of affine type at admissible levels. To do this, it is crucial to obtain knowledge of the singular vectors which generate the maximal submodules, with respect to which these VOAs appear as irreducible quotients, and therefore a substantial part of the text is devoted to
