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Efficacy of desmopressin in the treatment of nocturia: a double-blind placebo-controlled study in men.
OBJECTIVE: To investigate the efficacy and safety of oral desmopressin in the treatment of nocturia in men. PATIENTS AND METHODS: Men aged >/=18 years with verified nocturia (>or=two voids/night) and nocturnal urine production greater than their maximum functional bladder capacity were recruited. A 3-week dose-titration phase established the optimum desmopressin dose (0.1, 0.2 or 0.4 mg). After a
Restoration of tidal freshwater vegetation using controlled reduced tide (CRT) along the Schelde Estuary (Belgium)
Throughout the world, tidal marshes are being restored to obtain natural protection against recurring storm surges and sea level rise and to preserve the resources these habitats provide. Managed realignment, or breaching of the seaward dikes, is a restoration technique increasingly used; yet unsuitable site elevation has been a major constraint to habitat development. Controlled reduced tide (CRT
Nanostructured proton conducting polystyrene - poly(vinylphosphonic acid) block copolymers prepared via sequential anionic polymerizations
Poly(styrene-b-vinylphosphonic acid) diblock copolymers have been prepared via sequential anionic polymerization and evaluated as nanostructured polymer electrolytes. The ionic block copolymers were synthesized by first initiating the polymerization of styrene using n-butyllithium in tetrahydrofuran at −78 °C. 1,1-Diphenylethylene was then added to the living polystyryl anions before charging diet
Implementing affinity proteomics into the clinic - diagnosis and prediction of metastatic breast cancer
A biogeochemistry-based dynamic vegetation model and its application along a moisture gradient in the continental United States
We develop and evaluate a large-scale dynamic vegetation model, TEM-LPJ, which considers interactions among water, light and nitrogen in simulating ecosystem function and structure. We parameterized the model for three plant functional types (PFTs): a temperate deciduous forest, a temperate coniferous forest, and a temperate C-3 grassland. Model parameters were determined using data from forest st
The meaning of women's experiences of living with multiple sclerosis
We conducted a qualitative inquiry in order to describe the meaning of women's experiences of living with multiple sclerosis (MS). Multiple sclerosis is a chronic autoimmune disease of the central nervous system. The majority of persons living with MS are women. Living with MS has been described as difficult because of the uncertainty of the illness. Ten women with MS were interviewed and the inte
Personality disorder features as predictors of symptoms five years post-treatment.
Personality disorders are associated with dysfunction in a variety of areas. Recent longitudinal research has shown that personality disorders are also predictive of problems later in life, as well as of poor response to treatment of depression and anxiety. This study assessed whether personality disorder features were associated with psychiatric symptoms in a cohort of women treated for substance
Worrisome thoughts in children clinically referred for anxiety disorders
Administered a 31-item worry measure, based on criteria from the Diagnostic and Statistical Manual of Mental Disorders (3rd ed., rev.; American Psychiatric Association, 1987) for anxiety disorders, to referred children with anxiety disorders (n = 72) or attention deficit hyperactivity disorder (ADHD; n = 50), and to nonreferred, never psychiatrically ill controls (n = 55). Anxiety and ADHD groups
Initial-boundary value problems for parabolic equations
We prove new existence and uniqueness results for weak solutions to non-homogeneous initial-boundary value problems for parabolic equations modeled on the evolution of the p-Laplacian.
P-Selectin and P-Selectin Glycoprotein Ligand 1 Mediate Rolling of Activated CD8+ T Cells in Inflamed Colonic Venules.
BACKGROUND:: Activated T cells regulate inflammatory diseases in the intestinal tract; however, the adhesive mechanisms governing CD8 T-cell recruitment in the colon are not known. METHODS:: Herein, we used a graft-versus-host disease (GvHD) model to study CD8 T-cell rolling and adhesion in the large intestine by use of intravital fluorescence microscopy. Graft-versus-host disease was induced by t
Is there a unifying genetic factor predisposing to the metabolic syndrome?
Electron paramagnetic resonance study of the S=1/2 ground state of a radiolysis-generated manganese(III)-trimanganese(IV) form of [Mn-IV;O-4(6)(bipy)(6)](4+) (bipy=2,2'-bipyridine). Comparison with the photosynthetic Oxygen Evolving Complex
gamma-Ray irradiation at liquid nitrogen temperature of a dimethylformamide solution of the tetranuclear complex [(Mn4O6)-O-IV(bipy)(6)](4+) (bipy = 2,2'-bipyridine) allowed the generation of the first mixed-valence tetranuclear system containing Mn-III and Mn-IV ions and exhibiting a S = 1/2 ground state. The X-band EPR spectrum of this tetranuclear system has been obtained. Simulations have been
New Findings in PiZZ alpha(1)-Antitrypsin Deficiency-Related Panniculitis Demonstration of Skin Polymers and High Dosing Requirements of Intravenous Augmentation Therapy
Panniculitis is a recognized but unusual complication of a severe deficiency of alpha(1)-antitrypsin (AAT), with fewer than 100 cases described to date. Like the pathogenesis of emphysema in severe PiZZ deficiency of AAT, panniculitis has been hypothesized to be an inflammatory process, possibly related to Z AAT polymer formation and to an unopposed anti-inflammatory screen in the context of defic
Gene Transfer to Repopulating Human CD34(+) Cells Using Amphotropic-, GALV-, or RD114-Pseudotyped HIV-1-Based Vectors from Stable Producer Cells.
A hardware acceleration platform for digital holographic imaging
Gonadotoxic cancer treatment in males-a reason for andrological counselling?
LBF:s exkursion till Samos 13-19 maj 2007.
Mutual information in random Boolean models of regulatory networks
The amount of mutual information contained in the time series of two elements gives a measure of how well their activities are coordinated. In a large, complex network of interacting elements, such as a genetic regulatory network within a cell, the average of the mutual information over all pairs, ⟨I⟩, is a global measure of how well the system can coordinate its internal dynamics. We study this a
Hydrodynamics of surface swimming in leopard frogs (Rana pipiens)
The kinematics of swimming frogs have been studied extensively in the past and, based on these results, hypotheses regarding the hydrodynamics of frog swimming can be generated. To test these hypotheses we used digital particle image velocimetry (DPIV) to quantify the flow structure of the wake produced by the feet during the propulsion phase of the kick of surface swimming frogs (Rana pipiens). T
