Profile hidden Markov models provide a sensitive method for performing sequence database search and aligning multiple sequences. One of the drawbacks of the hidden Markov model is that the conserved amino acids are not emphasized, but signal and noise are treated equally. For this reason, the number of estimated emission parameters is often enormous. Focusing the analysis on conserved residues onl

The mechanisms of neutral dissociation of oxygen molecules in the excitation energy range 15–25 eV have been studied in a dispersed fluorescence experiment. By detecting the fluorescence from excited oxygen atoms, we find that neutral superexcited O2 states below 20 eV dissociate into O(g.s.)+O(3s,3p). At higher excitation energies (hν=20–25 eV) the curve-crossing interactions following excitation

Statins have been reported to exert anti-inflammatory actions and protect against septic organ dysfunction. Herein, we hypothesized that simvastatin may attenuate neutrophil activation and lung damage in abdominal sepsis. Male C57BL/6 mice were pretreated with simvastatin (0.5 or 10 mg/kg) before CLP. In separate groups, mice received an anti-CD40L antibody or a CXCR2 antagonist (SB225002) prior t

The aim of the study was to investigate and compare the ability to make inferences in three groups of children ranging from 5;2 to 10;9 years: 10 children with cerebral palsy (CP), 10 children with spina bifida and hydrocephalus (SBH) and 10 children with pragmatic language impairment (PLI). The relationship between inferential and literal comprehension was investigated by analysing atypical respo

BACKGROUND:: Flow cytometry allows the use of several antibodies in addition to light scatter, and most flow cytometers will provide at least seven measurements on each cell passing through the laser beam. A skilled microscopist will classify at least 14 cell classes in bone marrow or blood. Our goal was to use the seven parameters available in our flow cytometer to provide a reliable differential

Background. The recommended treatment for chronic musculoskeletal pain is multidisciplinary, with a cognitive approach. The aim of this study was to investigate health-related quality of life (HRQoL) outcome after a multidisciplinary treatment with a cognitive approach. Methods. A total of 131 subjects who participated in a multidisciplinary rehabilitation programme (2005-2008) were studied at bas

INTRODUCTION: Data on human atrial repolarization are scarce since the QRS complex normally obscures its ECG trace. In the present study, consecutive patients with third-degree AV block were studied to better describe the human Ta wave. METHODS AND RESULTS: Forty patients (mean age 75 years, 17 men) were included. All anti-arrhythmic drugs were discontinued before ECG recording. Standard 12-lead E

A compact planar multiple-input-multiple-output (MIMO) antenna system of four elements with similar radiation characteristics is proposed for the whole 2.4-GHz WLAN band. It consists of two proximity-coupled fed microstrip square ring patch antennas and two lambda/4 microstrip slot antennas of the same linear polarization. These two types of antennas are printed on different sides of the substrate

Lords and peasants : on jurisdiction in some baronies in Småland in the seventeenth century

Om James Bond på film.

BACKGROUND: Lung mast cells are stereotypically divided into connective tissue (MCTC) and mucosal (MCT) mast cells. This study tests the hypothesis that each of these subtypes can be divided further into site-specific populations created by the microenvironment within each anatomic lung compartment. METHODS: To study mast cells under non-inflamed conditions surgical resections and bronchial and tr

Introduction. This paper examines and synthesizes previous research in scientific collaboration, scholarly communication, scientific collaboratories, scientific disciplines, invisible colleges and virtual communities to identify factors that may impact the design, adoption and use of a collaboratory within librarianship and information science. Results. A taxonomy of factors that appear to impact

Kulturartikel om King Kong som biosuccé och kulturfenomen.